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    Mosapride Citrate (TAK-370; AS-4370)
    Mosapride Citrate (TAK-370; AS-4370)

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    This product is for research use only, not for human use. We do not sell to patients.
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    InvivoChem Cat #: V0994
    CAS #: 112885-42-4 Purity ≥98%

    Description: Mosapride Citrate (formerly AS-4370; TAK-370 citrate; AS-4370 citrate; TAK 370 citrate) is a novel, potent and selective gastroprokinetic agent that has been used in patients with upper gastrointestinal disorders. It acts as a selective 5HT4 agonist. Mosapride accelerates gastric emptying throughout the whole of the gastrointestinal tract in humans, and is used for the treatment of gastritis, gastroesophageal reflux disease, functional dyspepsia and irritable bowel syndrome.  

    References: Arzneimittelforschung. 1993 Oct;43(10):1078-83.

    Related CAS#: 636582-62-2 (citrate hydrate); 112885-41-3 (free base)

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    Molecular Weight (MW)614.02 
    FormulaC21H25ClFN3O3.C6H8O7 
    CAS No.112885-42-4 (citrate); 
    Storage-20℃ for 3 years in powder form
    -80℃ for 2 years in solvent
    Solubility (In vitro)DMSO: 90 mg/mL (146.6 mM) 
    Water: <1 mg/mL
    Ethanol: <1 mg/mL
    Other infoChemical Name: 4-Amino-5-chloro-2-ethoxy-N-[[4-[(4-fluorophenyl)methyl]morpholin-2-yl]methyl]benzamide citrate
    InChi Key: HUZTYZBFZKRPFG-UHFFFAOYSA-N
    InChi Code: InChI=1S/C21H25ClFN3O3.C6H8O7/c1-2-28-20-10-19(24)18(22)9-17(20)21(27)25-11-16-13-26(7-8-29-16)12-14-3-5-15(23)6-4-14;7-3(8)1-6(13,5(11)12)2-4(9)10/h3-6,9-10,16H,2,7-8,11-13,24H2,1H3,(H,25,27);13H,1-2H2,(H,7,8)(H,9,10)(H,11,12)
    SMILES Code: O=C(NCC1CN(CC2=CC=C(F)C=C2)CCO1)C3=CC(Cl)=C(N)C=C3OCC.OC(C(O)=O)(CC(O)=O)CC(O)=O
    SynonymsAS-4370; TAK-370 citrate; AS-4370 citrate; TAK 370 citrate; AS 4370 citrate; TAK370 citrate; AS4370 citrate


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