Immunotherapy for glioma is an attractive strategy yet faces significant barriers: (i) inefficient delivery across the blood-brain barrier (BBB), and (ii) a profoundly immunosuppressive microenvironment.
RNA molecules display remarkable heterogeneity in structure, dynamics, and function, yet methods for their precise visualization in living cells remain limited.
Secondary neuroinflammation is a major driver of progressive damage after traumatic brain injury (TBI), yet pharmacological interventions are limited by poor drug accumulation in the injured brain.
Myelin injury, a hallmark of several neurological diseases, is highly sensitive to glucose metabolism disruptions.
Both ER-associated degradation (ERAD) and autophagy play crucial roles in maintaining ER protein homeostasis.
Structural analysis of natural products remains challenging due to their inherent complexity and limited availability.
Per- and polyfluoroalkyl substances (PFAS) are synthetic chemicals with worldwide contamination and human exposure.
Background: Langerhans cells (LC) are epidermal dendritic cells building the skin's outermost immunological barrier and bridging innate and adaptive immune responses.
The invasion of human embryos in the uterus overcoming the maternal tissue barrier is a crucial step in embryo implantation and subsequent development.
Tetracycline antibiotics, extensively used in clinical and industrial applications, have been widely detected in aquatic environments.