Size | Price | Stock | Qty |
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100mg |
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250mg |
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500mg |
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1g |
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2g |
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5g |
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10g |
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Other Sizes |
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Purity: ≥98%
Venlafaxine (Wy45030; Wy-45030; Effexor, Effexor XR, Lanvexin, Viepax, and Trevilor) is an arylalkanolamine-based antidepressant that has been approved for use. It is a serotonin-norepinephrine reuptake inhibitor (SNRI) that is used to treat a variety of conditions, such as generalized anxiety disorder (GAD), major depressive disorder (MDD), panic disorder, and social phobia.
Targets |
5-HT
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ln Vitro |
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ln Vivo |
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Animal Protocol |
Male Sprague-Dawley rats weighing 180-230 grams
10, 30, 100 mg/kg IP; one hour prior to p-chloramphetamine hydrochloride (p-CA; 10 mg/kg; i.p.) |
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References |
Molecular Formula |
C17H28CLNO2
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Molecular Weight |
313.86
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Exact Mass |
313.18
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Elemental Analysis |
C, 54.90; H, 7.05; Cl, 9.53; N, 11.30; O, 8.60; S, 8.62
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CAS # |
99300-78-4
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Appearance |
Solid powder
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SMILES |
CN(C)CC(C1=CC=C(C=C1)OC)C2(CCCCC2)O.Cl
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InChi Key |
QYRYFNHXARDNFZ-UHFFFAOYSA-N
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InChi Code |
InChI=1S/C17H27NO2.ClH/c1-18(2)13-16(17(19)11-5-4-6-12-17)14-7-9-15(20-3)10-8-14;/h7-10,16,19H,4-6,11-13H2,1-3H3;1H
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Chemical Name |
1-[2-(dimethylamino)-1-(4-methoxyphenyl)ethyl]cyclohexan-1-ol;hydrochloride
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Synonyms |
Naramig; GR-85548A; Amerge; GR 85548A; GR85548A; Naratriptan HCl; Naratriptan Hydrochloride
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HS Tariff Code |
2935.90.6000
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Storage |
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month |
Shipping Condition |
Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)
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Solubility (In Vitro) |
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Preparing Stock Solutions | 1 mg | 5 mg | 10 mg | |
1 mM | 3.1861 mL | 15.9307 mL | 31.8613 mL | |
5 mM | 0.6372 mL | 3.1861 mL | 6.3723 mL | |
10 mM | 0.3186 mL | 1.5931 mL | 3.1861 mL |
*Note: Please select an appropriate solvent for the preparation of stock solution based on your experiment needs. For most products, DMSO can be used for preparing stock solutions (e.g. 5 mM, 10 mM, or 20 mM concentration); some products with high aqueous solubility may be dissolved in water directly. Solubility information is available at the above Solubility Data section. Once the stock solution is prepared, aliquot it to routine usage volumes and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles.
Calculation results
Working concentration: mg/mL;
Method for preparing DMSO stock solution: mg drug pre-dissolved in μL DMSO (stock solution concentration mg/mL). Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation::Take μL DMSO stock solution, next add μL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O,mix and clarify.
(1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
(2) Be sure to add the solvent(s) in order.
NCT Number | Recruitment | interventions | Conditions | Sponsor/Collaborators | Start Date | Phases |
NCT00667121 | Active Recruiting |
Drug: venlafaxine Drug: tamoxifen citrate Drug: gabapentin |
Breast Cancer Depression Hot Flashes |
Mayo Clinic | March 16, 2011 | N/A |
NCT03532477 | Recruiting | Drug: Venlafaxine | Obesity, Morbid | Norwegian University of Science and Technology |
November 2, 2016 | N/A |
NCT05023278 | Completed | Drug: Venlafaxine 37.5 MG Drug: Placebo |
Acute Pain Chronic Pain Knee Pain Chronic Neuropathic Pain |
University of California, San Francisco |
May 10, 2021 | Phase 4 |
NCT04639193 | Recruiting | Drug: Venlafaxine Drug: Placebo |
OSA Obstructive Sleep Apnea |
University of California, San Diego |
January 1, 2020 | Phase 2 |
NCT04961190 | Recruiting | Behavioral: Prolonged Exposure Therapy Drug: Pharmacotherapy with paroxetine or venlafaxine XR |
Posttraumatic Stress Disorder | University of Pennsylvania | May 25, 2022 | Phase 4 |