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      Tropicamide
      Tropicamide

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      This product is for research use only, not for human use. We do not sell to patients.
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      InvivoChem Cat #: V1181
      CAS #: 1508-75-4Purity ≥98%

      Description: Tropicamide (formerly Ro-17683; Ro 1-7683; trade names Mydral; Mydriafair; Mydriaticum; Mydrum), an approved medication used to dilate the pupil and help with eye examination, is a potent anticholinergic and a muscarinic receptor isoform M4 antagonist with important biological activity. It inhibits M4-muscarinic receptor with an IC50 of 8.0 nM. It is short acting drug for mydriasis and cycloplegia when applied as eye drops.  

      References: J Ophthalmol. 2015;2015:612728; Br J Pharmacol. 1993 Dec;110(4):1413-20.

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      Molecular Weight (MW)284.35 
      FormulaC17H20N2O2 
      CAS No.1508-75-4 
      Storage-20℃ for 3 years in powder form
      -80℃ for 2 years in solvent
      Solubility (In vitro)DMSO: 57 mg/mL (200.5 mM)
      Water: <1 mg/mL
      Ethanol: 57 mg/mL (200.5 mM)
      Other infoIUPAC/Chemical Name: N-ethyl-3-hydroxy-2-phenyl-N-(pyridin-4-ylmethyl)propanamide
      InChi Key: BGDKAVGWHJFAGW-UHFFFAOYSA-N
      InChi Code: InChI=1S/C17H20N2O2/c1-2-19(12-14-8-10-18-11-9-14)17(21)16(13-20)15-6-4-3-5-7-15/h3-11,16,20H,2,12-13H2,1H3
      SMILES Code: O=C(N(CC)CC1=CC=NC=C1)C(C2=CC=CC=C2)CO
      SynonymsRo-1-7683; Ro 1 7683; Mydral; Mydriafair; Mydriaticum; Mydrum; Ro 1-7683


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