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      Trazodone HCl (AF-116;, KB-831)
      Trazodone HCl (AF-116;, KB-831)

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      This product is for research use only, not for human use. We do not sell to patients.
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      InvivoChem Cat #: V0986
      CAS #: 25332-39-2Purity ≥98%

      Description: Trazodone HCl (Beneficat, KB 831, KB831, AF 1161, AF1161), the hydrochloride salt of Trazodone, is an approved antidepressant drug of the class of serotonin receptor antagonists and reuptake inhibitors (SARI) with the potential for treatment of anxiety disorders. Chemically, it is a phenylpiperazine analog with anti-anxiety (anxiolytic) and sleep-inducing (hypnotic) effects. Its side-effect profile and potential toxicity are considerably different from those of the original antidepressants (i.e., the monoamine oxidase inhibitors (MAOIs) and tricyclic antidepressants (TCAs). 

      References: Am J Case Rep. 2015 May 27;16:319-21; Drugs Aging. 1994 Apr;4(4):331-55.

      Related CAS #: 19794-93-5 (free); 25332-39-2 (HCl) 

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      Molecular Weight (MW)408.32 
      FormulaC19H22ClN5O.HCl 
      CAS No.25332-39-2 
      Storage-20℃ for 3 years in powder form
      -80℃ for 2 years in solvent
      Solubility (In vitro)DMSO: 4 mg/mL (9.79 mM)
      Water: <1 mg/mL
      Ethanol: <1 mg/mL
      SMILES CodeO=C1N(CCCN2CCN(C3=CC=CC(Cl)=C3)CC2)N=C4C=CC=CN41.[H]Cl
      SynonymsAF-1161, KB-831, KB 831, KB831, Trazodone, Trazodon, Beneficat, AF 1161, AF1161; Trazodone HCl


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      Trazodone HCl
      Electrocardiogram showing second-degree Mobitz type 1 atrioventricular block. Am J Case Rep. 2015 May 27;16:319-21.
      		 
      Trazodone HCl
      Telemetry showing second-degree Mobitz type 1 atrioventricular block recurring after every few beats of normal atrioventricular conduction. Am J Case Rep. 2015 May 27;16:319-21.
      		 
      Trazodone HCl
      Telemetry showing resolution of frequent second-degree Mobitz type 1 atrioventricular block. Am J Case Rep. 2015 May 27;16:319-21.

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