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Description: Tetrahydropapaverine (also known as Norlaudanosine HCl), one of the TIQs and an analogue of salsolinol and tetrahydropapaveroline, has been reported to have neurotoxic effects on dopamine neurons. Tetrahydropapaverine inhibits serotonin biosynthesis in serotonin-producing murine mastocytoma P815 cells with an IC50 of 7.5 μM and reduces tryptophan hydroxylase activity with an IC50 of 5.7 μM.
References: Life Sci. 2004 Sep 3;75(16):1949-57; Brain Res. 1997 Apr 18;754(1-2):260-8.
Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
This equation is commonly abbreviated as: C1V1 = C2V2
In vitro activity: Tetrahydropapaverine, one of the TIQs and an analogue of salsolinol and tetrahydropapaveroline, has been reported to have neurotoxic effects on dopamine neurons. Tetrahydropapaverine inhibits serotonin biosynthesis in serotonin-producing murine mastocytoma P815 cells with an IC50 of 7.5 μM and reduces tryptophan hydroxylase activity with an IC50 of 5.7 μM.
Life Sci. 2004 Sep 3;75(16):1949-57; Brain Res. 1997 Apr 18;754(1-2):260-8.
Purity ≥ 98%
COA
MSDS