| Size | Price | Stock | Qty |
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| 100mg |
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| 500mg |
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| 1g |
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Purity: ≥98%
Sulfameter (Bayrena; Sulfametoxydiazine; 5-Methoxysulfadiazine; NSC-683528; I-2586; SH-613) is a novel, long-acting sulfonamide antibacterial agent used as a leprostatic agent and also is used to treat UTIs/urinary tract infections. Sulfonamide antibiotics act by blocking the synthesis of dihydrofolic acid via inhibiting the enzyme DHPS/ dihydropteroate synthase. Sulfonamides are active against Gram positive bacteria and Gram negative bacteria. The mode of resistance is via the alteration of dihydropteroate synthase or alternative pathway for folic acid synthesis.
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| ln Vivo |
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| Animal Protocol |
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| References |
Int J Clin Pharmacol Biopharm.1979 Jun;17(6):260-3;Clin Pharmacol Ther.1969 Jul-Aug;10(4):591-4.
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| Molecular Formula |
C11H12N4O3S
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| Molecular Weight |
280.3
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| CAS # |
651-06-9
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| Related CAS # |
Sulfameter-d4;1189483-96-2;Sulfameter-13C6
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| SMILES |
S(C1C([H])=C([H])C(=C([H])C=1[H])N([H])[H])(N([H])C1=NC([H])=C(C([H])=N1)OC([H])([H])[H])(=O)=O
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| InChi Key |
GPTONYMQFTZPKC-UHFFFAOYSA-N
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| InChi Code |
InChI=1S/C11H12N4O3S/c1-18-9-6-13-11(14-7-9)15-19(16,17)10-4-2-8(12)3-5-10/h2-7H,12H2,1H3,(H,13,14,15)
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| Chemical Name |
4-amino-N-(5-methoxypyrimidin-2-yl)benzenesulfonamide
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| Synonyms |
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| Storage |
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month |
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| Shipping Condition |
Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)
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| Solubility (In Vitro) |
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| Preparing Stock Solutions | 1 mg | 5 mg | 10 mg | |
| 1 mM | 3.5676 mL | 17.8380 mL | 35.6761 mL | |
| 5 mM | 0.7135 mL | 3.5676 mL | 7.1352 mL | |
| 10 mM | 0.3568 mL | 1.7838 mL | 3.5676 mL |
*Note: Please select an appropriate solvent for the preparation of stock solution based on your experiment needs. For most products, DMSO can be used for preparing stock solutions (e.g. 5 mM, 10 mM, or 20 mM concentration); some products with high aqueous solubility may be dissolved in water directly. Solubility information is available at the above Solubility Data section. Once the stock solution is prepared, aliquot it to routine usage volumes and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles.
Calculation results
Working concentration： mg/mL；
Method for preparing DMSO stock solution： mg drug pre-dissolved in μL DMSO (stock solution concentration mg/mL). Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:：Take μL DMSO stock solution, next add μL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O，mix and clarify.
(1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
(2) Be sure to add the solvent(s) in order.
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