| Size | Price | Stock | Qty |
|---|---|---|---|
| 5mg |
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| 10mg |
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| Other Sizes |
| Targets |
Microbial Metabolite
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|---|---|
| ln Vitro |
The process of electrons moving from oxidizing to reducing agents is catalyzed by glucose oxidases, a subclass of oxidoreductases. The enzyme glucose oxidase releases hydrogen peroxide (H2O2) by using oxygen as an external electron acceptor. A wide range of commercial procedures employ glucose oxidase, such as enhancing food items' color and flavor, prolonging their shelf life, extracting glucose from dehydrated eggs, and removing oxygen from various juices and drinks [4].
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| References |
[1]. Konishi T, et al. Safety evaluation of glucose oxidase from Penicillium chrysogenum [published correction appears in Regul Toxicol Pharmacol. 2013 Aug;66(3):300]. Regul Toxicol Pharmacol. 2013;66(1):13-23.
[2]. Leskovac V, et al. Glucose oxidase from Aspergillus niger: the mechanism of action with molecular oxygen, quinones, and one-electron acceptors. Int J Biochem Cell Biol. 2005;37(4):731-750. [3]. Wang M, et al. Recent Advances in Glucose-Oxidase-Based Nanocomposites for Tumor Therapy. Small. 2019;15(51):e1903895. [4]. Khatami SH, et al. Glucose oxidase: Applications, sources, and recombinant production [published online ahead of print, 2021 Apr 11]. Biotechnol Appl Biochem. 2021;10.1002/bab.2165. |
| Additional Infomation |
β-D-glucose is d-glucose pyranose with a β-configuration of its anomeric carbon atom. It is an epitope and a metabolite in mice. It is the enantiomer of β-L-glucose. It is a major energy source for organisms. β-D-glucose is naturally found in fruits and other parts of plants, existing in a free state. It can be used for treatment with fluids and nutritional supplements.
Glucose oxidase has been studied for the treatment of upper respiratory tract infections. β-D-glucose is a metabolite found in or produced by Escherichia coli (K12 strain, MG1655 strain). (2R,3R,4S,5S,6R)-6-(hydroxymethyl)oxacyclohexane-2,3,4,5-tetraol has been reported in hops, Acer rubrum, and other organisms with relevant data. β-D-glucose pyranose is the β-isomer of D-glucose pyranose, a simple synthetic monosaccharide that can be used as an energy source. D-glucan can be oxidized in various tissues under both aerobic and anaerobic conditions via glycolysis, producing carbon dioxide, water, and ATP. Yeast polysaccharide, an insoluble β-1,3-glucan derived from the yeast cell wall, is a structural component with potential immunostimulatory activity. After administration, yeast polysaccharide can target, bind to, and activate certain Toll-like receptors, primarily TLR2 on leukocytes and dectin-1 on macrophages. Activation of TLR2 and dectin-1 can stimulate the release of pro-inflammatory mediators and enhance the innate immune response. β-D-glucan is a metabolite found or produced in Saccharomyces cerevisiae. See also: Yeast polysaccharide (note moved to). |
| Exact Mass |
154.026
|
|---|---|
| CAS # |
9001-37-0
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| Related CAS # |
26874-89-5;133947-06-5
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| PubChem CID |
64689
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| Appearance |
Typically exists as solid at room temperature
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| Density |
1.5±0.1 g/cm3
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| Boiling Point |
513.7±50.0 °C at 760 mmHg
|
| Flash Point |
226.8±23.6 °C
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| Vapour Pressure |
0.0±3.0 mmHg at 25°C
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| Index of Refraction |
1.603
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| LogP |
-0.75
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| Hydrogen Bond Donor Count |
5
|
| Hydrogen Bond Acceptor Count |
6
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| Rotatable Bond Count |
1
|
| Heavy Atom Count |
12
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| Complexity |
151
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| Defined Atom Stereocenter Count |
5
|
| SMILES |
C([C@@H]1[C@H]([C@@H]([C@H]([C@@H](O1)O)O)O)O)O
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| InChi Key |
WQZGKKKJIJFFOK-VFUOTHLCSA-N
|
| InChi Code |
InChI=1S/C6H12O6/c7-1-2-3(8)4(9)5(10)6(11)12-2/h2-11H,1H2/t2-,3-,4+,5-,6-/m1/s1
|
| Chemical Name |
(2R,3R,4S,5S,6R)-6-(hydroxymethyl)oxane-2,3,4,5-tetrol
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| HS Tariff Code |
2934.99.9001
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| Storage |
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month |
| Shipping Condition |
Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)
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| Solubility (In Vitro) |
H2O :~50 mg/mL
|
|---|---|
| Solubility (In Vivo) |
Solubility in Formulation 1: 50 mg/mL (Infinity mM) in PBS (add these co-solvents sequentially from left to right, and one by one), clear solution; with sonication.
(Please use freshly prepared in vivo formulations for optimal results.) |
Calculation results
Working concentration： mg/mL；
Method for preparing DMSO stock solution： mg drug pre-dissolved in μL DMSO (stock solution concentration mg/mL). Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:：Take μL DMSO stock solution, next add μL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O，mix and clarify.
(1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
(2) Be sure to add the solvent(s) in order.
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