| Size | Price | Stock | Qty |
|---|---|---|---|
| 5mg |
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| 10mg |
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| Other Sizes |
| ln Vitro |
Adrenocorticotropic hormone (ACTH) is a hormone produced by the anterior pituitary gland that regulates the production of cortisol and androgens and is associated with Addison's disease, Cushing's syndrome and Cushing's disease[1].
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|---|---|
| References |
| Molecular Formula |
C79H110F3N21O22S
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|---|---|
| Molecular Weight |
1794.90
|
| Related CAS # |
ACTH (1-14)
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| Sequence |
Ser-Tyr-Ser-Met-Glu-His-Phe-Arg-Trp-Gly-Lys-Pro-Val-GlySYSMEHFRWGKPVG
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| SequenceShortening |
SYSMEHFRWGKPVG
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| Appearance |
White to off-white solid
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| Synonyms |
Adrenocorticotropic Hormone Fragment 1-14 TFA
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| HS Tariff Code |
2934.99.9001
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| Storage |
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month Note: 请将本产品存放在密封保护的环境中，避免受潮。 |
| Shipping Condition |
Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)
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| Solubility (In Vitro) |
H2O : ~100 mg/mL (~55.71 mM; with sonication)
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|---|---|
| Solubility (In Vivo) |
Solubility in Formulation 1: 25 mg/mL (13.93 mM) in PBS (add these co-solvents sequentially from left to right, and one by one), Clear solution; Need ultrasonic.
(Please use freshly prepared in vivo formulations for optimal results.) |
| Preparing Stock Solutions | 1 mg | 5 mg | 10 mg | |
| 1 mM | 0.5571 mL | 2.7857 mL | 5.5713 mL | |
| 5 mM | 0.1114 mL | 0.5571 mL | 1.1143 mL | |
| 10 mM | 0.0557 mL | 0.2786 mL | 0.5571 mL |
*Note: Please select an appropriate solvent for the preparation of stock solution based on your experiment needs. For most products, DMSO can be used for preparing stock solutions (e.g. 5 mM, 10 mM, or 20 mM concentration); some products with high aqueous solubility may be dissolved in water directly. Solubility information is available at the above Solubility Data section. Once the stock solution is prepared, aliquot it to routine usage volumes and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles.
Calculation results
Working concentration： mg/mL；
Method for preparing DMSO stock solution： mg drug pre-dissolved in μL DMSO (stock solution concentration mg/mL). Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:：Take μL DMSO stock solution, next add μL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O，mix and clarify.
(1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
(2) Be sure to add the solvent(s) in order.
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