| Size | Price | Stock | Qty |
|---|---|---|---|
| 5mg |
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| 10mg |
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| 50mg |
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| 100mg |
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| Other Sizes |
| ln Vivo |
(S)-CE-123 (6.0, 12.0, 24.0 mg/kg; intraperitoneal injection; 30 minutes before the test) significantly attenuated the effects of bubenazine (TBZ) on the pressure lever and food intake. (S)-CE-123 alone did not significantly differ from the carrier-treated rats [1].
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|---|---|
| Animal Protocol |
Animal/Disease Models:Trained male rats (adult male Sprague-Dawley rats) [1]
Doses: 6.0, 12.0, 24.0 mg/kg Route of Administration: Intraperitoneal injection; 30 minutes before the test Experimental Results: Reduced the effect of TBZ (1.0 mg/kg) on the pressure lever and food intake. |
| References |
|
| Molecular Formula |
C17H15NOS2
|
|---|---|
| Molecular Weight |
313.44
|
| CAS # |
2378384-49-5
|
| Appearance |
Typically exists as solids at room temperature
|
| SMILES |
O=[S@@](CC1=CN=CS1)C(C2=CC=CC=C2)C3=CC=CC=C3
|
| HS Tariff Code |
2934.99.9001
|
| Storage |
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month |
| Shipping Condition |
Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)
|
| Solubility (In Vitro) |
May dissolve in DMSO (in most cases), if not, try other solvents such as H2O, Ethanol, or DMF with a minute amount of products to avoid loss of samples
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|---|---|
| Solubility (In Vivo) |
Solubility in Formulation 1: 10% DMSO + 15%Tween 80 +75% 0.9% saline
Preparation of saline: Dissolve 0.9 g of sodium chloride in 100 mL ddH₂ O to obtain a clear solution. (Please use freshly prepared in vivo formulations for optimal results.) |
| Preparing Stock Solutions | 1 mg | 5 mg | 10 mg | |
| 1 mM | 3.1904 mL | 15.9520 mL | 31.9040 mL | |
| 5 mM | 0.6381 mL | 3.1904 mL | 6.3808 mL | |
| 10 mM | 0.3190 mL | 1.5952 mL | 3.1904 mL |
*Note: Please select an appropriate solvent for the preparation of stock solution based on your experiment needs. For most products, DMSO can be used for preparing stock solutions (e.g. 5 mM, 10 mM, or 20 mM concentration); some products with high aqueous solubility may be dissolved in water directly. Solubility information is available at the above Solubility Data section. Once the stock solution is prepared, aliquot it to routine usage volumes and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles.
Calculation results
Working concentration： mg/mL；
Method for preparing DMSO stock solution： mg drug pre-dissolved in μL DMSO (stock solution concentration mg/mL). Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:：Take μL DMSO stock solution, next add μL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O，mix and clarify.
(1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
(2) Be sure to add the solvent(s) in order.
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