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    Procainamide HCl
    Procainamide HCl

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    This product is for research use only, not for human use. We do not sell to patients.
    Number: - + Pieces(InventoryPieces)
    InvivoChem Cat #: V0410
    CAS #: 614-39-1Purity ≥98%

    Description: Procainamide HCl (known also as Procainamide hydrochloride; Procanbid; Procan) is an approved anti-arrhythmic drug that is used to treat cardiac arrhythmia by acting as a potent sodium channel blocker, and also a DNA methyltransferase inhibitor. Procainamide hydrochloride is the hydrochloride salt preparation of Procainamide which demonstrates antiarrhythmic effects correlated with blockade of the Na+ channels.  

    References: JPharmacol Rep. 2016 Jun;68(3):654-61.

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    Molecular Weight (MW)271.79
    CAS No.614-39-1
    Storage-20℃ for 3 years in powder form
    -80℃ for 2 years in solvent
    Solubility (In vitro)DMSO: 54 mg/mL (198.6 mM)
    Water: N/A
    Ethanol: 54 mg/mL (198.6 mM)
    Other info

    Chemical Name: 4-amino-N-[2-(diethylamino)ethyl]benzamide;hydrochloride


    InChi Code: InChI=1S/C13H21N3O.ClH/c1-3-16(4-2)10-9-15-13(17)11-5-7-12(14)8-6-11;/h5-8H,3-4,9-10,14H2,1-2H3,(H,15,17);1H


    SynonymsPronestyl; Procainamide HCl;  Procanbid; Procaine Amide; Procan; Procapan; Procainamide Hydrochloride; Procamide; Pronestyl; Procan SR; Procanbid; 
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    In Vitro

    In vitro activity: Procainamide hydrochloride is an anti-arrhythmic agent and is used to treat cardiac arrhythmia; induces rapid block of the batrachotoxin(BTX)-activated sodium channels of the heart muscle and acts as antagonist to long gating closures.

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    ReferencesZamponi GW, et al. Dual actions of procainamide on batrachotoxin-activated sodium channels: open channel block and prevention of inactivation. Biophys J. 1993 Dec;65(6):2324-34.

    These protocols are for reference only. InvivoChem does not independently validate these methods.


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