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    Procainamide HCl
    Procainamide HCl

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    This product is for research use only, not for human use. We do not sell to patients.
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    InvivoChem Cat #: V0410
    CAS #: 614-39-1Purity ≥98%

    Description: Procainamide HCl(known also as Procainamide hydrochloride) is an anti-arrhythmic drug that is used to treat cardiac arrhythmia by acting as a potent sodium channel blocker, and also a DNA methyltransferase inhibitor, used in the treatment of cardiac arrhythmias. Procainamide hydrochloride is the hydrochloride salt preparation of Procainamide, a potent blocker of Na+ channels. Procainamide demonstrates antiarrhythmic effects correlated with blockade of the Na+ channels. Procainamide hydrochloride is an inhibitor of DNA methyltransferase. 

    References: JPharmacol Rep. 2016 Jun;68(3):654-61.

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    Molecular Weight (MW)271.79
    FormulaC13H22ClN3O
    CAS No.614-39-1
    Storage-20℃ for 3 years in powder form
    -80℃ for 2 years in solvent
    Solubility (In vitro)DMSO: 54 mg/mL (198.6 mM)
    Water: N/A
    Ethanol: 54 mg/mL (198.6 mM)
    Other info

    Chemical Name: 4-amino-N-[2-(diethylamino)ethyl]benzamide;hydrochloride

    InChi Key: ABTXGJFUQRCPNH-UHFFFAOYSA-N

    InChi Code: InChI=1S/C13H21N3O.ClH/c1-3-16(4-2)10-9-15-13(17)11-5-7-12(14)8-6-11;/h5-8H,3-4,9-10,14H2,1-2H3,(H,15,17);1H

    SMILES Code: CCN(CC)CCNC(=O)C1=CC=C(C=C1)N.Cl

    SynonymsPronestyl; Procainamide Hcl; Procapan; Procainamide Hydrochloride; Procamide; Pronestyl; Procanbid; Procaine Amide; Procan; Procan SR; Procanbid; 
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    In Vitro

    In vitro activity: Procainamide hydrochloride is an anti-arrhythmic agent and is used to treat cardiac arrhythmia; induces rapid block of the batrachotoxin(BTX)-activated sodium channels of the heart muscle and acts as antagonist to long gating closures.

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    ReferencesZamponi GW, et al. Dual actions of procainamide on batrachotoxin-activated sodium channels: open channel block and prevention of inactivation. Biophys J. 1993 Dec;65(6):2324-34.


    These protocols are for reference only. InvivoChem does not independently validate these methods.

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