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Description: Procainamide HCl(known also as Procainamide hydrochloride) is an anti-arrhythmic drug that is used to treat cardiac arrhythmia by acting as a potent sodium channel blocker, and also a DNA methyltransferase inhibitor, used in the treatment of cardiac arrhythmias. Procainamide hydrochloride is the hydrochloride salt preparation of Procainamide, a potent blocker of Na+ channels. Procainamide demonstrates antiarrhythmic effects correlated with blockade of the Na+ channels. Procainamide hydrochloride is an inhibitor of DNA methyltransferase.
References: JPharmacol Rep. 2016 Jun;68(3):654-61.
Chemical Name: 4-amino-N-[2-(diethylamino)ethyl]benzamide;hydrochloride
InChi Key: ABTXGJFUQRCPNH-UHFFFAOYSA-N
InChi Code: InChI=1S/C13H21N3O.ClH/c1-3-16(4-2)10-9-15-13(17)11-5-7-12(14)8-6-11;/h5-8H,3-4,9-10,14H2,1-2H3,(H,15,17);1H
SMILES Code: CCN(CC)CCNC(=O)C1=CC=C(C=C1)N.Cl
Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
This equation is commonly abbreviated as: C1V1 = C2V2
In vitro activity: Procainamide hydrochloride is an anti-arrhythmic agent and is used to treat cardiac arrhythmia; induces rapid block of the batrachotoxin(BTX)-activated sodium channels of the heart muscle and acts as antagonist to long gating closures.
Purity > 98%
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