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    ONO 8430506
    ONO 8430506

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    This product is for research use only, not for human use. We do not sell to patients.
    Number: - + Pieces(InventoryPieces)
    InvivoChem Cat #: V2197
    CAS #: 1354805-08-5Purity ≥98%

    Description: ONO8430506(ONO-8430506) is a novel and potent autotaxin inhibitor that enhances the antitumor effect of paclitaxel in a breast cancer model. Lysophosphatidic acid (LPA) is a bioactive lipid mediator that elicits a number of biological functions, including smooth muscle contraction, cell motility, proliferation, and morphological change. LPA is endogenously produced by autotaxin (ATX) from extracellular lysophosphatidylcholine (LPC) in plasma.

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    Molecular Formula: C27H28FN3O3
    Exact Mass: 461.2115
    Molecular Weight: 461.5374
    Elemental Analysis: C, 70.26; H, 6.12; F, 4.12; N, 9.10; O, 10.40

    Synonym: ONO-8430506; ONO 8430506; ONO8430506

    Chemical Name: 4-(2-(9-(4-fluorobenzyl)-5,6,8,9-tetrahydro-7H-pyrrolo[2,3-b:5,4-c']dipyridin-7-yl)-2-oxoethyl)bicyclo[2.2.1]heptane-1-carboxylic acid

    InChi Key: SGSFONPFVRRJLS-UHFFFAOYSA-N

    InChi Code: InChI=1S/C27H28FN3O3/c28-19-5-3-18(4-6-19)15-31-22-16-30(13-7-20(22)21-2-1-12-29-24(21)31)23(32)14-26-8-10-27(17-26,11-9-26)25(33)34/h1-6,12H,7-11,13-17H2,(H,33,34)

    SMILES Code: O=C(C1(C2)CCC2(CC(N(C3)CCC4=C3N(CC5=CC=C(F)C=C5)C6=NC=CC=C64)=O)CC1)O


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