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    Nelonicline
    Nelonicline

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    This product is for research use only, not for human use. We do not sell to patients.
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    InvivoChem Cat #: V4407
    CAS #: 1026134-63-3Purity ≥98%

    Description: Nelonicline (aslo known as ABT-126) is a novel, potent and selective neuronal nicotinic receptor agonist. Nelonicline is potentially useful for the treatment of Alzheimer's diseases. ABT-126 may be useful to reduce dyskinesias in both early- and later-stage Parkinson's disease. Accumulating evidence suggests that the α7 subtype of nicotinic acetylcholine receptors (nAChRs) plays a key role in inflammatory processes, thought to be involved in the pathophysiology of neuropsychiatric diseases, such as schizophrenia and Alzheimer's disease.

    References: WO2015168616A1.


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    Nelonicline

    Name: Nelonicline
    CAS#: 1026134-63-3
    Chemical Formula: C17H19N3OS
    Exact Mass: 313.1249
    Molecular Weight: 313.42
    Elemental Analysis: C, 65.15; H, 6.11; N, 13.41; O, 5.10; S, 10.23
    Storage-20℃ for 3 years in powder form
    -80℃ for 2 years in solvent
    Technical InformationSynonym: ABT-126; ABT126; ABT 126
    IUPAC/Chemical Name: 2-(((3R,4r,5S,7s)-1-azaadamantan-4-yl)oxy)-5-phenyl-1,3,4-thiadiazole
    InChi Key: QZDCYUCETTWCMO-OFTMQHFLSA-N
    InChi Code: InChI=1S/C17H19N3OS/c1-2-4-12(5-3-1)16-18-19-17(22-16)21-15-13-6-11-7-14(15)10-20(8-11)9-13/h1-5,11,13-15H,6-10H2/t11-,13-,14+,15+
    SMILES Code: C1(C(S2)=NN=C2O[[email protected]@H]3[[email protected]]4C[[email protected]]5C[[email protected]@H]3CN(C4)C5)=CC=CC=C1


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