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    Nalidixic acid (NSC-82174)
    Nalidixic acid (NSC-82174)

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    This product is for research use only, not for human use. We do not sell to patients.
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    InvivoChem Cat #: V1407
    CAS #: 389-08-2Purity ≥98%

    Description: Nalidixic acid (also known as NSC-82174), a synthetic 1,8-naphthyridine antimicrobial agent, is the first of the synthetic quinolone antibiotic with a limited bacteriocidal spectrum. It is an inhibitor of the A subunit of bacterial DNA gyrase. Nalidixic acid is effective primarily against gram-negative bacteria, with minor anti-gram-positive activity. At lower concentrations, it acts in a bacteriostatic manner; At higher concentrations, it is bactericidal. 

    References:  Int J Antimicrob Agents. 2012 Jul;40(1):9-17.

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    Molecular Weight (MW)232.24 
    FormulaC12H12N2O3 
    CAS No.389-08-2 
    Storage-20℃ for 3 years in powder form
    -80℃ for 2 years in solvent
    Solubility (In vitro)DMSO: 6 mg/mL (25.8 mM) 
    Water: <1 mg/mL
    Ethanol: <1 mg/mL 
    Other info

    Chemical Name: 1-ethyl-7-methyl-4-oxo-1,8-naphthyridine-3-carboxylic acid

    InChi Key: MHWLWQUZZRMNGJ-UHFFFAOYSA-N

    InChi Code: InChI=1S/C12H12N2O3/c1-3-14-6-9(12(16)17)10(15)8-5-4-7(2)13-11(8)14/h4-6H,3H2,1-2H3,(H,16,17)

    SMILES Code: O=C(C1=CN(CC)C2=C(C=CC(C)=N2)C1=O)O

    SynonymsNSC-82174; NSC 82174; NSC82174; Nalidixic Acid, Nevigramon, Neggram, Wintomylon, WIN 18,320


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