Size | Price | Stock | Qty |
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250mg |
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500mg |
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1g |
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2g |
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10g |
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Other Sizes |
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Purity: ≥98%
Mexiletine HCl (Mexitil, Mexiletene, KO-1173, KO 1173; KO1173), the hydrochloride salt of Mexiletine, is an anti-arythmic drug of the Class IB group approved for use in the treatment of abnormal heart rhythms. It act as a non-selective voltage-gated sodium channel blocker that inhibits sodium channels. Mexiletine is also a local anesthetic which is structurally similar to lidocaine.
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ln Vivo |
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Animal Protocol |
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References |
Curr Med Chem.2015;22(11):1400-13;Curr Pain Headache Rep.2010Apr;14(2):145-50.
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Molecular Formula |
C11H17NO.HCL
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Molecular Weight |
215.72
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CAS # |
5370-01-4
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SMILES |
Cl[H].O(C1C(C([H])([H])[H])=C([H])C([H])=C([H])C=1C([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])N([H])[H]
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InChi Key |
NFEIBWMZVIVJLQ-UHFFFAOYSA-N
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InChi Code |
InChI=1S/C11H17NO.ClH/c1-8-5-4-6-9(2)11(8)13-7-10(3)12;/h4-6,10H,7,12H2,1-3H3;1H
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Chemical Name |
1-(2,6-dimethylphenoxy)propan-2-amine hydrochloride
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Synonyms |
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Storage |
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month |
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Shipping Condition |
Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)
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Solubility (In Vitro) |
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Preparing Stock Solutions | 1 mg | 5 mg | 10 mg | |
1 mM | 4.6356 mL | 23.1782 mL | 46.3564 mL | |
5 mM | 0.9271 mL | 4.6356 mL | 9.2713 mL | |
10 mM | 0.4636 mL | 2.3178 mL | 4.6356 mL |
*Note: Please select an appropriate solvent for the preparation of stock solution based on your experiment needs. For most products, DMSO can be used for preparing stock solutions (e.g. 5 mM, 10 mM, or 20 mM concentration); some products with high aqueous solubility may be dissolved in water directly. Solubility information is available at the above Solubility Data section. Once the stock solution is prepared, aliquot it to routine usage volumes and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles.
Calculation results
Working concentration: mg/mL;
Method for preparing DMSO stock solution: mg drug pre-dissolved in μL DMSO (stock solution concentration mg/mL). Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation::Take μL DMSO stock solution, next add μL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O,mix and clarify.
(1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
(2) Be sure to add the solvent(s) in order.