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    MDR-652
    MDR-652

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    This product is for research use only, not for human use. We do not sell to patients.
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    InvivoChem Cat #: V2184
    CAS #: 1933528-96-1 Purity ≥98%

    Description:MDR-652 is a novel and highly specific and efficacious transient receptor potential vanilloid 1 (TRPV1) ligand with agonist activity. The Kis are 11.4 and 23.8 nM for hTRPV1 and rTRPV1, respectively. The EC50s are 5.05 and 93 nM for hTRPV1 and rTRPV1, respectively. agonist discovered to be a strong topical analgesic.

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    Molecular Formula: C22H23ClFN3O2S
    Exact Mass: 447.1184
    Molecular Weight: 447.95

    Synonym: MDR-652; MDR652; MDR 652;

    Chemical Name: 1-((2-(tert-butyl)-4-(3-chlorophenyl)thiazol-5-yl)methyl)-3-(3-fluoro-4-(hydroxymethyl)phenyl)urea

    InChi Key: HKMPJRGWSUCANB-UHFFFAOYSA-N

    InChi Code: InChI=1S/C22H23ClFN3O2S/c1-22(2,3)20-27-19(13-5-4-6-15(23)9-13)18(30-20)11-25-21(29)26-16-8-7-14(12-28)17(24)10-16/h4-10,28H,11-12H2,1-3H3,(H2,25,26,29)

    SMILES Code: ClC1=CC=CC(C2=C(CNC(NC3=CC=C(CO)C(F)=C3)=O)SC(C(C)(C)C)=N2)=C1


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