Size | Price | Stock | Qty |
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1g |
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2g |
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5g |
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10g |
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Other Sizes |
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Purity: ≥98%
Labetalol HCl (ch15719W; AH5158; Normodyne, Albetol, Trandate, Apo-Labetalol, Dilevalol), the hydrochloride salt of Labetalol, is a competitive and dual antagonist of alpha1-adrenergic and beta-adrenergic receptors with potential antihypertensive properties. The medication labetalol was approved to treat hypertension.
Targets |
α1-adrenergic receptor; β-adrenergic receptor
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References |
Molecular Formula |
C19H25CLN2O3
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Molecular Weight |
364.866404294968
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Exact Mass |
364.16
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Elemental Analysis |
C, 62.55; H, 6.91; Cl, 9.72; N, 7.68; O, 13.15
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CAS # |
32780-64-6
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Appearance |
White to off-white crystalline powder
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SMILES |
CC(CCC1=CC=CC=C1)NCC(C2=CC(=C(C=C2)O)C(=O)N)O.Cl
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InChi Key |
WQVZLXWQESQGIF-UHFFFAOYSA-N
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InChi Code |
InChI=1S/C19H24N2O3.ClH/c1-13(7-8-14-5-3-2-4-6-14)21-12-18(23)15-9-10-17(22)16(11-15)19(20)24;/h2-6,9-11,13,18,21-23H,7-8,12H2,1H3,(H2,20,24);1H
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Chemical Name |
2-hydroxy-5-[1-hydroxy-2-(4-phenylbutan-2-ylamino)ethyl]benzamide;hydrochloride
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Synonyms |
AH-5158 hydrochloride; Sch-15719W; AH5158 hydrochloride; Sch15719W; AH 5158 hydrochloride; Sch 15719W; Normodyne; Trandate; Albetol; Apo-Labetalol; Dilevalol
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HS Tariff Code |
2934.99.9001
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Storage |
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month |
Shipping Condition |
Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)
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Solubility (In Vitro) |
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Preparing Stock Solutions | 1 mg | 5 mg | 10 mg | |
1 mM | 2.7407 mL | 13.7035 mL | 27.4070 mL | |
5 mM | 0.5481 mL | 2.7407 mL | 5.4814 mL | |
10 mM | 0.2741 mL | 1.3704 mL | 2.7407 mL |
*Note: Please select an appropriate solvent for the preparation of stock solution based on your experiment needs. For most products, DMSO can be used for preparing stock solutions (e.g. 5 mM, 10 mM, or 20 mM concentration); some products with high aqueous solubility may be dissolved in water directly. Solubility information is available at the above Solubility Data section. Once the stock solution is prepared, aliquot it to routine usage volumes and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles.
Calculation results
Working concentration: mg/mL;
Method for preparing DMSO stock solution: mg drug pre-dissolved in μL DMSO (stock solution concentration mg/mL). Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation::Take μL DMSO stock solution, next add μL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O,mix and clarify.
(1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
(2) Be sure to add the solvent(s) in order.
NCT Number | Recruitment | interventions | Conditions | Sponsor/Collaborators | Start Date | Phases |
NCT05551104 | Recruiting | Drug: Oral Nifedipine Drug: Oral Labetalol |
Postpartum Complication Maternal Hypertension |
Loma Linda University | December 2023 | Not Applicable |
NCT04298034 | Recruiting | Drug: Labetalol, Nifedipine | Preeclampsia Hypertension in Pregnancy |
Medical College of Wisconsin | July 17, 2020 | Phase 3 |
NCT04755764 | Recruiting | Drug: Labetalol Drug: Atenolol Drug: Nifedipine |
Systolic Hypertension Pregnancy Related |
Marshall University | March 3, 2021 | N/A |
NCT05309460 | Not yet recruiting | Drug: Labetalol Oral Tablet Drug: NIFEdipine ER |
Postpartum Preeclampsia Hypertension in Pregnancy |
Nebraska Methodist Health System |
June 6, 2022 | Phase 4 |
NCT06093893 | Not yet recruiting | Drug: Dexmedetomidine Drug: Nicardipine |
Hypotensive Anesthesia Orthognathic Surgery |
Boston Medical Center | March 2024 | Phase 4 |