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    GNF351
    GNF351

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    This product is for research use only, not for human use. We do not sell to patients.
    Number: - + Pieces(InventoryPieces)
    InvivoChem Cat #: V4534
    CAS #: 1227634-69-6Purity ≥98%

    Description: GNF351 is a  novel and potent full aryl hydrocarbon receptor (AHR) antagonist. GNF351 competes with a photoaffinity AHR ligand for binding to the AHR with an IC50 of 62 nM. GNF351 is minimal toxicity in mouse or human keratinocytes.  

    References: J Invest Dermatol. 2015 May;135(5):1320-1328.


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    GNF351

    Name: GNF351
    CAS#: 1227634-69-6
    Chemical Formula: C24H25N7
    Exact Mass: 411.2171
    Molecular Weight: 411.513
    Elemental Analysis: C, 70.05; H, 6.12; N, 23.83
    Storage-20℃ for 3 years in powder form
    -80℃ for 2 years in solvent
    Technical InformationSynonym: GNF351; GNF-351 GNF 351.
    IUPAC/Chemical Name: 8-(2-(1H-indol-3-yl)ethyl)-9-isopropyl-2-(5-methylpyridin-3-yl)-9H-purin-6-amine
    InChi Key: WWERDIHAUJLVQP-UHFFFAOYSA-N
    InChi Code: InChI=1S/C24H25N7/c1-14(2)31-20(9-8-16-13-27-19-7-5-4-6-18(16)19)28-21-22(25)29-23(30-24(21)31)17-10-15(3)11-26-12-17/h4-7,10-14,27H,8-9H2,1-3H3,(H2,25,29,30)
    SMILES Code: NC1=C2N=C(CCC3=CNC4=C3C=CC=C4)N(C(C)C)C2=NC(C5=CC(C)=CN=C5)=N1


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