Size | Price | Stock | Qty |
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1g |
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5g |
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10g |
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25g |
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Other Sizes |
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Purity: ≥98%
Glutathione (GSH; γ-L-Glutamyl-L-cysteinyl-glycine) is an endogenous tripeptide acting as an antioxidant for scavenging oxygen-derived free radicals. It acts by conjugating to drugs and increasing their water solubility for excretion.
ln Vitro |
One of the most common non-protein thiols found in living cells is L-reduced glutathione. Important biological processes in organisms include the synthesis of proteins and DNA, enzyme activity, metabolism, and cell protection, all of which depend on L-reduced glutathione. L-reduced glutathione has been found to be a sign of oxidative stress and has the ability to scavenge oxygen free radicals [1].
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References |
[1]. Pereira-Rodrigues N, et al. Electrocatalytic activity of cobalt phthalocyanine CoPc adsorbed on a graphite electrode for the oxidation of reduced L-glutathione (GSH) and the reduction of its disulfide (GSSG) at physiological pH. Bioelectrochemistry. 2007 Jan;70(1):147-54.
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Molecular Formula |
C10H17N3O6S
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Molecular Weight |
307.32
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Exact Mass |
307.0838
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CAS # |
70-18-8
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Related CAS # |
L-Glutathione reduced-13C2,15N;815610-65-2
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SMILES |
S([H])C([H])([H])[C@@]([H])(C(N([H])C([H])([H])C(=O)O[H])=O)N([H])C(C([H])([H])C([H])([H])[C@@]([H])(C(=O)O[H])N([H])[H])=O
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Synonyms |
GSH NSC-400639 NSC400639Glutatiol NSC 400639 L-GlutathioneGlutathione
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Storage |
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month |
Shipping Condition |
Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)
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Solubility (In Vitro) |
H2O : ~62.5 mg/mL (~203.37 mM)
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Preparing Stock Solutions | 1 mg | 5 mg | 10 mg | |
1 mM | 3.2539 mL | 16.2697 mL | 32.5394 mL | |
5 mM | 0.6508 mL | 3.2539 mL | 6.5079 mL | |
10 mM | 0.3254 mL | 1.6270 mL | 3.2539 mL |
*Note: Please select an appropriate solvent for the preparation of stock solution based on your experiment needs. For most products, DMSO can be used for preparing stock solutions (e.g. 5 mM, 10 mM, or 20 mM concentration); some products with high aqueous solubility may be dissolved in water directly. Solubility information is available at the above Solubility Data section. Once the stock solution is prepared, aliquot it to routine usage volumes and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles.
Calculation results
Working concentration: mg/mL;
Method for preparing DMSO stock solution: mg drug pre-dissolved in μL DMSO (stock solution concentration mg/mL). Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation::Take μL DMSO stock solution, next add μL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O,mix and clarify.
(1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
(2) Be sure to add the solvent(s) in order.