My cart
In the shopping cart is not goods, to choose and buy!
  • Product Name
  • Size
  • Quantity
  • Amount
    Selected items : 0 pieces Total : CHECK OUT()
    Duloxetine HCl (LY-248686 HCl)
    Duloxetine HCl (LY-248686 HCl)

    Price:
    Market Price:

    This product is for research use only, not for human use. We do not sell to patients.
    Number: - + Pieces(InventoryPieces)
    InvivoChem Cat #: V1016
    CAS #: 136434-34-9 Purity ≥98%

    Description: Duloxetine HCl (formerly LY-248686 HCl; LY248686; trade names Cymbalta; Yentreve), the hydrochloride salt of Duloxetine which is an approved antidepressant medication, is a potent serotonin-norepinephrine reuptake inhibitor (SNRI) with potential anti-depressive activity. It inhibits SNRI with a Ki of 4.6 nM. Duloxetine has been used for treating various indications such as major depressive disorders, generalized anxiety disorder (GAD), fibromyalgia and neuropathic pain as well as stress urinary incontinence. Duloxetine is marketed under the brand name Cymbalta among others.

    References: Life Sci. 1988;43(24):2049-57. 

    Related CAS#: 116539-59-4 (Free base); 949095-98-1 (Para-Naphthol duloxetine, a Duloxetine metabolite); 1435727-97-1 (Duloxetine D3 HCl); 916135-70-1 (N-Methyl Duloxetine)

    Customer Validation
    Official Supplier of
    • VE
    • OF
    • YALE
    • hhmi
    • 香港大学
    Related Products
    Publications Citing InvivoChem Products
    • Physicochemical and Storage Information
    • Protocol
    • Quality Control Documentation
    • Related Biological Data
    • Customer Review
    Molecular Weight (MW)333.88 
    FormulaC18H19NOS.HCl 
    CAS No.136434-34-9  (HCl)
    Storage-20℃ for 3 years in powder form
    -80℃ for 2 years in solvent
    Solubility (In vitro)DMSO: 67 mg/mL (200.7 mM) 
    Water: <1 mg/mL
    Ethanol: <1 mg/mL
    Solubility (In vivo)2% DMSO+30% PEG 300+ddH2O:  30 mg/mL
    SynonymsLY-227942; LY248686; LY-248686 HCl; Duloxetine; LY-248686; LY227942; Cymbalta; (S)-Duloxetine; Yentreve; Duloxetine HCl; duloxetine hydrochloride; duloxetine, (+)-isomer; HCl, LY 227942; LY 248686 


    • Molarity Calculator
    • Dilution Calculator
    • The molarity calculator equation

      Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

      • Mass
      • Concentration
      • Volume
      • Molecular Weight *
      • =
      • ×
      • ×
    • The dilution calculator equation

      Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

      This equation is commonly abbreviated as: C1V1 = C2V2

      • Concentration (start)
      • ×
      • Volume (start)
      • =
      • Concentration (final)
      • ×
      • Volume (final)
      • ×
      • =
      • ×
      • C1
      •  
      • V1
      •  
      • C2
      •  
      • V2

    These protocols are for reference only. InvivoChem does not independently validate these methods.

    评论

      Home Prev Next Last page / pices

      发评论

      ×
      Your information is safe with us. * Required Fields.
      Products are for research use only;  We do not sell to patients
      Tel: 1-708-310-1919
      Fax: 1-708-557-7486
      Subscribe to our E-newsletter
      • Name*
      • *
      • E-mail*
      • *
      • instructions:
      • *
      Copyright 2020 InvivoChem LLC | All Rights Reserved
      prompt
      Do you confirm the receipt?