Size | Price | Stock | Qty |
---|---|---|---|
5mg |
|
||
10mg |
|
||
50mg |
|
||
100mg |
|
||
250mg |
|
||
500mg |
|
||
Other Sizes |
|
ln Vitro |
The study conducted growth factor fingerprinting of 1-beta-D-Arabic Syriac glycosyl clock pin (ara-C) and found that it was present in 13 cell lines generated from murine myeloma, myeloid tumor-like, and mastocytoma. The outer 100-fold folds into each other between the most and least sensitive spectra. The amount of cellular deoxycytidine triphosphate (2'-Deoxycytidine-5'-triphosphate, dCTP) was discovered to be inversely linked with obesity[1], indicating that if cells are exposed to ara-C. Phosphoethanolamine glycol ester transferase uses deoxycytidine triphosphate trisodium salt as a substrate [2].
|
---|---|
References |
Molecular Formula |
C9H16N3O13P3
|
---|---|
Molecular Weight |
467.15693
|
Exact Mass |
532.935
|
CAS # |
109909-44-6
|
Related CAS # |
Deoxycytidine triphosphate;2056-98-6
|
PubChem CID |
53486366
|
Appearance |
Colorless to light yellow liquid
|
LogP |
0.713
|
Hydrogen Bond Donor Count |
3
|
Hydrogen Bond Acceptor Count |
13
|
Rotatable Bond Count |
8
|
Heavy Atom Count |
31
|
Complexity |
805
|
Defined Atom Stereocenter Count |
3
|
SMILES |
P(=O)([O-])(OP(=O)([O-])OP(=O)([O-])O[H])OC([H])([H])[C@]1([H])[C@]([H])(C([H])([H])[C@]([H])(N2C(N=C(C([H])=C2[H])N([H])[H])=O)O1)O[H].[Na+].[Na+].[Na+]
|
InChi Key |
WBIPTAOOMJEGQO-MILVPLDLSA-K
|
InChi Code |
InChI=1S/C9H16N3O13P3.3Na/c10-7-1-2-12(9(14)11-7)8-3-5(13)6(23-8)4-22-27(18,19)25-28(20,21)24-26(15,16)17;;;/h1-2,5-6,8,13H,3-4H2,(H,18,19)(H,20,21)(H2,10,11,14)(H2,15,16,17);;;/q;3*+1/p-3/t5-,6+,8+;;;/m0.../s1
|
Chemical Name |
trisodium;[[[(2R,3S,5R)-5-(4-amino-2-oxopyrimidin-1-yl)-3-hydroxyoxolan-2-yl]methoxy-oxidophosphoryl]oxy-oxidophosphoryl] hydrogen phosphate
|
Synonyms |
Cytidine 2deoxy 5(tetrahydrogen triphosphate) trisodium salt; Cytidine 5(tetrahydrogen triphosphate) 2deoxy trisodium salt; dCTP Thymus
|
HS Tariff Code |
2934.99.9001
|
Storage |
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month Note: Please store this product in a sealed and protected environment, avoid exposure to moisture. |
Shipping Condition |
Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)
|
Solubility (In Vitro) |
H2O : ~250 mg/mL (~468.96 mM)
DMSO :< 1 mg/mL |
---|---|
Solubility (In Vivo) |
Solubility in Formulation 1: 100 mg/mL (187.58 mM) in PBS (add these co-solvents sequentially from left to right, and one by one), clear solution; with sonication.
 (Please use freshly prepared in vivo formulations for optimal results.) |
Preparing Stock Solutions | 1 mg | 5 mg | 10 mg | |
1 mM | 2.1406 mL | 10.7030 mL | 21.4059 mL | |
5 mM | 0.4281 mL | 2.1406 mL | 4.2812 mL | |
10 mM | 0.2141 mL | 1.0703 mL | 2.1406 mL |
*Note: Please select an appropriate solvent for the preparation of stock solution based on your experiment needs. For most products, DMSO can be used for preparing stock solutions (e.g. 5 mM, 10 mM, or 20 mM concentration); some products with high aqueous solubility may be dissolved in water directly. Solubility information is available at the above Solubility Data section. Once the stock solution is prepared, aliquot it to routine usage volumes and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles.
Calculation results
Working concentration: mg/mL;
Method for preparing DMSO stock solution: mg drug pre-dissolved in μL DMSO (stock solution concentration mg/mL). Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation::Take μL DMSO stock solution, next add μL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O,mix and clarify.
(1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
(2) Be sure to add the solvent(s) in order.