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    Clonidine HCl
    Clonidine HCl

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    This product is for research use only, not for human use. We do not sell to patients.
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    InvivoChem Cat #: V1114
    CAS #: 4205-91-8Purity ≥98%

    Description: Clonidine HCl (Catapres, Duraclon, Jenloga, Catapres-TTS, and Kapvay), the hydrochloride salt of clonidine, is a direct-acting α2 adrenergic agonist with antihypertensive effects. It activates α2 adrenergic with an ED50 of 0.02±0.01 mg/kg. Clonidine is a sympathomimetic drug that has been used for the treatment of high blood pressure, attention deficit hyperactivity disorder (ADHD), anxiety disorders, withdrawal (from either alcohol, opioids, or smoking), migraine, menopausal flushing, diarrhea, and certain pain conditions. Clonidine treats high blood pressure by stimulating α2-receptors in the brain, which decreases peripheral vascular resistance, lowering blood pressure.

    References: Clin Pharmacol Ther. 1980 Aug;28(2):167-76; Am J Physiol. 1997 Nov;273(5 Pt 2):R1569-71.

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    Molecular Weight (MW)266.5 
    FormulaC9H9Cl2N3.HCl 
    CAS No.4205-91-8 
    Storage-20℃ for 3 years in powder form
    -80℃ for 2 years in solvent
    Solubility (In vitro)DMSO: 53 mg/mL (198.9 mM)  
    Water: NA
    Ethanol: 53 mg/mL (198.9 mM)  
    Other info

    Chemical Name: 1H-Imidazol-2-amine, N-(2,6-dichlorophenyl)-4,5-dihydro-, monohydrochloride (9CI)

    InChi Key: ZNIFSRGNXRYGHF-UHFFFAOYSA-N

    InChi Code: InChI=1S/C9H9Cl2N3.ClH/c10-6-2-1-3-7(11)8(6)14-9-12-4-5-13-9;/h1-3H,4-5H2,(H2,12,13,14);1H

    SMILES Code: ClC1=C(NC2=NCCN2)C(Cl)=CC=C1.[H]Cl

    Synonyms

    Clonidine monohydrochloride; Catapres, Duraclon, Jenloga, Catapres-TTS, and Kapvay


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