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    Benidipine HCl
    Benidipine HCl

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    This product is for research use only, not for human use. We do not sell to patients.
    Number: - + Pieces(InventoryPieces)
    InvivoChem Cat #: V0885
    CAS #: 91599-74-5Purity ≥98%

    Description: Benidipine HCl (formerly SC-278724, KW-3049 HCl; trade names Sular; Coniel) is the hydrochloride salt form of benidipine which is a DHP/dihydropyridine calcium channel blocker/CCB with anti-hypertensive activity. It has been approved for the treatment high blood pressure and angina pectoris. It also inhibits aldosterone-induced MCR activation. In addition, benidipine Hydrochloride has been reported to reduce oxidative stress. Benidipine is sold in the United States under the proprietary name Sular.  

    References: Methods Find Exp Clin Pharmacol. 2005 Apr;27(3):167-71; J Cardiovasc Pharmacol. 1999 Aug;34(2):248-53.

    Related CAS #: 91599-74-5 (HCl); 105979-17-7 (free base);

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    Molecular Weight (MW)542.02 
    FormulaC28H31N3O6.HCl 
    CAS No.91599-74-5 
    Storage-20℃ for 3 years in powder form
    -80℃ for 2 years in solvent
    Solubility (In vitro)DMSO: 8 mg/mL (14.8 mM)
    Water: <1 mg/mL
    Ethanol: <1 mg/mL
    Solubility (In vivo)

    Chemical Name: 3-((R)-1-benzylpiperidin-3-yl) 5-methyl (R)-2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate hydrochloride

    InChi Key: KILKDKRQBYMKQX-MIPPOABVSA-N

    InChi Code: InChI=1S/C28H31N3O6.ClH/c1-18-24(27(32)36-3)26(21-11-7-12-22(15-21)31(34)35)25(19(2)29-18)28(33)37-23-13-8-14-30(17-23)16-20-9-5-4-6-10-20;/h4-7,9-12,15,23,26,29H,8,13-14,16-17H2,1-3H3;1H/t23-,26-;/m1./s1

    SMILES Code: O=C(C1=C(C)NC(C)=C(C(O[[email protected]]2CN(CC3=CC=CC=C3)CCC2)=O)[[email protected]@H]1C4=CC=CC([N+]([O-])=O)=C4)OC.[H]Cl

    SynonymsKW-3049;  KW3049; Coniel; Benidipine Hydrochloride; KW 3049;


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