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      Arecoline HBr
      Arecoline HBr

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      This product is for research use only, not for human use. We do not sell to patients.
      Number： - + Pieces（InventoryPieces）
      InvivoChem Cat #: V1187
      CAS #: 300-08-3Purity ≥98%

      Description: Arecoline HBr (NSC56321, NSC-56321), the hydrobromide salt of Arecoline which is a naturally occurring alkaloid found in the betel nut of the Areca palm, is a potent agonist of muscarinic acetylcholine receptor with the potential to be used in treating dementia. It activates the M1, M2, M3, M4, and M5 subtype of muscarinic acetylcholine receptors with EC50 values of 7, 95, 11, 410, and 69 nM, respectively. 

      References: Chin J Physiol. 2000 Mar 31;43(1):23-8.

      Related CAS #: 300-08-3 (HBr)   63-75-2 (free)   61-94-9 (HCl)    

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      Molecular Weight (MW)236.11 
      FormulaC8H13NO2.HBr 
      CAS No.300-08-3 
      Storage-20℃ for 3 years in powder form
      -80℃ for 2 years in solvent
      Solubility (In vitro)DMSO: 47 mg/mL (199.1 mM) 
      Water: 47 mg/mL (199.1 mM) 
      Ethanol: 10 mg/mL (42.4 mM) 
      Other info

      Chemical Name: methyl 1-methyl-1,2,5,6-tetrahydropyridine-3-carboxylate hydrobromide

      InChi Key: AXOJRQLKMVSHHZ-UHFFFAOYSA-N

      InChi Code: InChI=1S/C8H13NO2.BrH/c1-9-5-3-4-7(6-9)8(10)11-2;/h4H,3,5-6H2,1-2H3;1H

      SMILES Code: O=C(C1=CCCN(C)C1)OC.Br

      Synonyms

      NSC 56321, Arecoline Hydrobromide, Arecoline HBr, NSC56321, NSC-56321, Arecoline


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