| Size | Price | Stock | Qty |
|---|---|---|---|
| 100mg |
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| 1g |
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| Other Sizes |
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| References |
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|---|---|
| Additional Infomation |
N-acetyl-beta-neuraminic acid is n-Acetylneuraminic acid with beta configuration at the anomeric centre. It has a role as an epitope. It is functionally related to a beta-neuraminic acid. It is a conjugate acid of a N-acetyl-beta-neuraminate.
An N-acyl derivative of neuraminic acid. N-acetylneuraminic acid occurs in many polysaccharides, glycoproteins, and glycolipids in animals and bacteria. (From Dorland, 28th ed, p1518) 5-N-Acetyl-beta-D-neuraminic acid has been reported in Artemia salina and Homo sapiens with data available. A subcategory of mucins that contain SIALIC ACID. |
| Molecular Formula |
C11H21NO9
|
|---|---|
| Molecular Weight |
311.287
|
| Exact Mass |
309.105
|
| CAS # |
131-48-6
|
| Related CAS # |
N-Acetylneuraminic acid-13C;64162-77-2;N-Acetylneuraminic acid-13C-1;1032998-24-5;N-Acetylneuraminic acid-13C-2;220803-19-0;N-Acetylneuraminic acid-13C-3
|
| PubChem CID |
445063
|
| Appearance |
White to off-white solid powder
|
| Density |
1.6±0.1 g/cm3
|
| Boiling Point |
762.3±60.0 °C at 760 mmHg
|
| Melting Point |
184-186 °C (dec.)(lit.)
|
| Flash Point |
414.8±32.9 °C
|
| Vapour Pressure |
0.0±5.8 mmHg at 25°C
|
| Index of Refraction |
1.581
|
| LogP |
-3.98
|
| Hydrogen Bond Donor Count |
7
|
| Hydrogen Bond Acceptor Count |
9
|
| Rotatable Bond Count |
5
|
| Heavy Atom Count |
21
|
| Complexity |
403
|
| Defined Atom Stereocenter Count |
6
|
| SMILES |
CC(=O)N[C@@H]1[C@H](C[C@](O[C@H]1[C@@H]([C@@H](CO)O)O)(C(=O)O)O)O
|
| InChi Key |
DXQYQJUKDZLOFX-JKKVJPCISA-N
|
| InChi Code |
InChI=1S/C11H19NO8.H2O/c1-4(10(16)17)19-9-7(12-5(2)14)11(18)20-6(3-13)8(9)15/h4,6-9,11,13,15,18H,3H2,1-2H3,(H,12,14)(H,16,17)1H2/t4-,6?,7+,8-,9-,11+/m1./s1
|
| Chemical Name |
(2R)-2-(((2S,3S,4R,5S)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-4-yl)oxy)propanoic acid hydrate
|
| Synonyms |
NPC-09 Ace-ER UX-001 Neu-5Ac N-Acetylneuraminic Acid Hydrate Neu5Ac HydrateSA-ER AceERAceneuramic acidNANA Hydrate
|
| HS Tariff Code |
2934.99.9001
|
| Storage |
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month Note: Please store this product in a sealed and protected environment (e.g. under nitrogen), avoid exposure to moisture. |
| Shipping Condition |
Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)
|
| Solubility (In Vitro) |
H2O : ~125 mg/mL (~404.18 mM)
|
|---|---|
| Solubility (In Vivo) |
Solubility in Formulation 1: 100 mg/mL (323.34 mM) in PBS (add these co-solvents sequentially from left to right, and one by one), clear solution; with sonication (<60°C).
(Please use freshly prepared in vivo formulations for optimal results.) |
| Preparing Stock Solutions | 1 mg | 5 mg | 10 mg | |
| 1 mM | 3.2124 mL | 16.0622 mL | 32.1244 mL | |
| 5 mM | 0.6425 mL | 3.2124 mL | 6.4249 mL | |
| 10 mM | 0.3212 mL | 1.6062 mL | 3.2124 mL |
*Note: Please select an appropriate solvent for the preparation of stock solution based on your experiment needs. For most products, DMSO can be used for preparing stock solutions (e.g. 5 mM, 10 mM, or 20 mM concentration); some products with high aqueous solubility may be dissolved in water directly. Solubility information is available at the above Solubility Data section. Once the stock solution is prepared, aliquot it to routine usage volumes and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles.
Calculation results
Working concentration： mg/mL；
Method for preparing DMSO stock solution： mg drug pre-dissolved in μL DMSO (stock solution concentration mg/mL). Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:：Take μL DMSO stock solution, next add μL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O，mix and clarify.
(1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
(2) Be sure to add the solvent(s) in order.
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