E3 Ligase Ligand-Linker Conjugates

E3 Ligase Ligand-Linker Conjugate, which is one part of Proteolysis Targeting Chimeric Molecules (PROTACs), incorporates a ligand for the E3 ubiquitin ligase and a linker.These conjugates can be used to create PROTACs that target proteins for ubiquitination and destruction after being coupled to the ligand for the target protein (for example, JQ1 for the BRD4 protein or Molibresib for the BET protein). Currently, a number of PROTACs that specifically target BET, the estrogen receptor (ER), the androgen receptor, etc. have been identified to demonstrate good biological activity.

E3 Ligase Ligand-Linker Conjugates related products

Structure Cat No. Product Name CAS No. Product Description
V82495 Azido-PEG5-S-methyl ethanethioate 1352221-64-7 Azido-PEG5-S-methyl ethanethioate is a PROTAC (PROteolysis TArgeting Chimera) linker and belongs to the PEG (Polyethylene glycol) class, may be utilized to prepare PROTAC molecules.
V82421 Azido-PEG7-CH2COOH 1446411-32-0 Azido-PEG7-CH2COOH is a PROTAC (PROteolysis TArgeting Chimera) linker and belongs to the PEG category, may be utilized to prepare PROTAC molecules.
V82444 Benzyl-PEG1-propanol 131326-24-4 Benzyl-PEG1-propanol is a PROTAC (PROteolysis TArgeting Chimera) linker of the Polyethylene glycol (PEG) category, may be utilized to prepare PROTAC protein degraders.
V82469 Benzyl-PEG12-alcohol 2218463-17-1 Benzyl-PEG12-alcohol is a PROTAC (PROteolysis TArgeting Chimera) linker of the Polyethylene glycol (PEG) category, may be utilized to prepare PROTAC protein degraders.
V82419 Benzyl-PEG2-acid 91555-65-6 Benzyl-PEG2-acid is a PROTAC (PROteolysis TArgeting Chimera) linker of the Polyethylene glycol (PEG) category, may be utilized to prepare PROTAC protein degraders.
V82410 Benzyl-PEG3-acid 127457-63-0 Benzyl-PEG3-acid is a PROTAC (PROteolysis TArgeting Chimera) linker of the Polyethylene glycol (PEG) category, may be utilized to prepare PROTAC protein degraders.
V82446 Benzyl-PEG4-amine 86770-76-5 Benzyl-PEG4-amine is a PROTAC (PROteolysis TArgeting Chimera) linker of the Polyethylene glycol (PEG) category, may be utilized to prepare PROTAC protein degraders.
V82470 Benzyl-PEG4-Azido 86770-71-0 Benzyl-PEG4-Azido is a PROTAC (PROteolysis TArgeting Chimera) linker and belongs to the PEG (Polyethylene glycol) class.
V82479 Benzyl-PEG4-Ots 89346-82-7 Benzyl-PEG4-Ots is a PROTAC (PROteolysis TArgeting Chimera) linker of the Polyethylene glycol (PEG) category.
V82434 Benzyl-PEG4-THP 1027926-86-8 Benzyl-PEG4-THP is a PROTAC (PROteolysis TArgeting Chimera) linker of the Polyethylene glycol (PEG) category, may be utilized to prepare PROTAC protein degraders.
V82407 Benzyl-PEG5-acid 2514948-41-3 Benzyl-PEG5-acid is a PROTAC (PROteolysis TArgeting Chimera) linker of the Polyethylene glycol (PEG) category, may be utilized to prepare PROTAC protein degraders.
V82450 Benzyl-PEG5-NHBoc 2064292-55-1 Benzyl-PEG5-NHBoc is a PROTAC (PROteolysis TArgeting Chimera) linker of the Polyethylene glycol (PEG) category, may be utilized to prepare PROTAC protein degraders.
V82497 Benzyl-PEG6-amine 86770-78-7 Benzyl-PEG6-amine is a PROTAC (PROteolysis TArgeting Chimera) linker of the Polyethylene glycol (PEG) category, may be utilized to prepare PROTAC protein degraders.
V82451 Benzyl-PEG6-t-butyl ester 2148296-00-6 Benzyl-PEG6-t-butyl ester is a PROTAC (PROteolysis TArgeting Chimera) linker of the Polyethylene glycol (PEG) category, may be utilized to prepare PROTAC protein degraders.
V82489 Benzyl-PEG6-THP 230620-73-2 Benzyl-PEG6-THP is a PROTAC (PROteolysis TArgeting Chimera) linker of the Polyethylene glycol (PEG) category, may be utilized to prepare PROTAC protein degraders.
V82477 Benzyl-PEG8-alcohol 477775-73-8 Benzyl-PEG8-alcohol is a PROTAC (PROteolysis TArgeting Chimera) linker of the Polyethylene glycol (PEG) category, may be utilized to prepare PROTAC protein degraders.
V82397 Benzyl-PEG8-Ots 1144113-17-6 Benzyl-PEG8-Ots is a PROTAC (PROteolysis TArgeting Chimera) linker of the PEG category.
V82439 Benzyl-PEG9-Ots 393517-91-4 Benzyl-PEG9-Ots is a PROTAC (PROteolysis TArgeting Chimera) linker of the Polyethylene glycol (PEG) category, may be utilized to prepare PROTAC protein degraders.
V82485 Biotin-PEG3-propargyl 1421701-68-9 Biotin-PEG3-propargyl is a PROTAC (PROteolysis TArgeting Chimera) linker and belongs to the PEG (Polyethylene glycol) class, may be utilized to prepare PROTAC molecules.
V82504 Biotin-PEG3-SH 1244028-52-1 Biotin-PEG3-SH is a PROTAC (PROteolysis TArgeting Chimera) linker of the Polyethylene glycol (PEG) category, may be utilized to prepare PROTAC protein degraders.
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