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    Y15
    Y15

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    This product is for research use only, not for human use. We do not sell to patients.
    Number: - + Pieces(InventoryPieces)
    InvivoChem Cat #: V3389
    CAS #: 4506-66-5 Purity ≥98%

    Description: Y15 (also known as FAK inhibitor Y15 and FAK Inhibitor 14) is a novel, potent, specific and direct inhibitor of focal adhesion kinase (FAK) which blocks phosphorylation of Y397 with an IC50 value of about 1 μM. Y15 decreases viability, clonogenicity, and cell attachment in thyroid cancer cell lines and synergizes with targeted therapeutics. Y15 was shown to decrease cancer growth in vitro and in vivo. Y15 inhibits its autophosphorylation activity, decreases the viability of cancer cells, and blocks tumor growth.

    References: Cell Cycle. 2009 Aug;8(15):2435-43.Oncotarget. 2014 Sep 15;5(17):7945-59. 

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    Y15

    Name: Y15
    CAS#: 4506-66-5
    Chemical Formula: C6H14Cl4N4
    Exact Mass:
    Molecular Weight: 284.006 
    Storage-20℃ for 3 years in powder form
    -80℃ for 2 years in solvent
    Technical InformationSynonym: FAK Inhibitor 14; FAK Inhibitor Y15; Y15 hydrochloride; Y15 tetrahydrochloride; Y 15; Y-15.
    Chemical Name: 1,2,4,5-benzenetetramine tetrahydrochloride
    InChi Key: BZDGCIJWPWHAOF-UHFFFAOYSA-N
    InChi Code: InChI=1S/C6H10N4.4ClH/c7-3-1-4(8)6(10)2-5(3)9;;;;/h1-2H,7-10H2;4*1H
    SMILES Code: NC1=CC(N)=C(N)C=C1N.[H]Cl.[H]Cl.[H]Cl.[H]Cl


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