| Size | Price | Stock | Qty |
|---|---|---|---|
| 250mg |
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| 500mg |
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| Other Sizes |
| Targets |
Turanose targets inflammatory and metabolic pathways. As a sucrose isomer, it has anti-inflammatory and fat-regulating activities. The compound has research potential for obesity and related chronic diseases. It may interact with metabolic enzymes and inflammatory mediators. Turanose is used as a natural sweetener and as a stabilizing agent in drug formulations.
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| ln Vitro |
In vitro, Turanose has anti-inflammatory and fat-regulating activities. It is a sucrose isomer found in honey. The compound is used in research on obesity and related chronic diseases. Its anti-inflammatory effects have been characterized in various cell-based assays. Turanose modulates adipogenesis in cell culture models. Its metabolic effects have been studied in vitro.
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| ln Vivo |
In vivo, Turanose has research potential for obesity and related chronic diseases. It has anti-inflammatory and fat-regulating activities. The compound is a naturally occurring isomer of sucrose found in honey. It is used as a natural sweetener and as a stabilizing agent in drug formulations. Further in vivo studies are ongoing to fully characterize its therapeutic potential.
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| Enzyme Assay |
Turanose enzyme assays involve measuring its effects on metabolic enzymes and inflammatory mediators. Anti-inflammatory activity is assessed by measuring inhibition of pro-inflammatory cytokine production. Fat-regulating activity is assessed by measuring adipogenesis and lipid accumulation in adipocyte cultures. Metabolic enzyme activities such as sucrase or glucosidase may be assessed. Assays are performed in appropriate buffer systems with positive controls such as known anti-inflammatory agents.
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| Cell Assay |
Turanose cell-based assays are conducted in adipocytes, immune cells, and other relevant cell types. Cells are cultured in appropriate media at 37°C with 5% CO2 and treated with Turanose at varying concentrations. Cell viability is assessed by MTT or CCK-8 assays. Anti-inflammatory activity is assessed by measuring cytokine levels by ELISA. Fat-regulating activity is assessed by measuring lipid accumulation using Oil Red O staining or triglyceride assays. Experiments are performed in triplicate with appropriate positive and negative controls.
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| Animal Protocol |
Turanose in vivo studies are conducted in animal models of obesity and metabolic diseases. Animals are treated with Turanose via oral administration or diet. Body weight, food intake, and metabolic parameters such as blood glucose, insulin, and lipid levels are measured. Adipose tissue weight and histology are assessed. Inflammatory markers in serum and tissues are measured. Animals are monitored for clinical signs. Tissues and blood samples are collected for histopathological and biochemical analysis at study endpoints. Studies are conducted in accordance with institutional animal care guidelines.
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| ADME/Pharmacokinetics |
Turanose (MW 342.30 g/mol, C12H22O11) is a sucrose isomer found in honey. It is a non-hygroscopic compound that forms prisms from water and alcohol. It has a very sweet taste and exhibits mutarotation ([α]D20 +27.3° → +75.8° in water). The compound is soluble in water. It is stable as a lyophilized powder at -20°C for up to 36 months. Pharmacokinetic parameters such as half-life, bioavailability, and tissue distribution would be determined in species-specific studies.
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| Toxicity/Toxicokinetics |
Turanose is generally recognized as safe as a natural sugar. The compound is a naturally occurring isomer of sucrose found in honey. It has anti-inflammatory and fat-regulating activities. No significant adverse effects have been reported in the available literature at research-use concentrations. The compound is intended for research use only. Standard laboratory safety practices should be employed when handling this compound. Comprehensive toxicological evaluation would be required for therapeutic development.
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| References | |
| Additional Infomation |
Turanose is a naturally occurring isomer of sucrose found in honey with anti-inflammatory and fat-regulating activities. It has research potential for obesity and related chronic diseases. The compound is used as a natural sweetener and stabilizing agent in drug formulations. Its molecular formula is C12H22O11 with a molecular weight of 342.30 g/mol. All applications are limited to non-human research use.
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| Molecular Formula |
C12H22O11
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|---|---|
| Molecular Weight |
342.2965
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| Exact Mass |
342.116
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| CAS # |
547-25-1
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| PubChem CID |
54301978
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| Appearance |
White to off-white solid powder
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| Density |
1.8±0.1 g/cm3
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| Boiling Point |
693.3±55.0 °C at 760 mmHg
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| Melting Point |
170 °C (dec.)(lit.)
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| Flash Point |
373.1±31.5 °C
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| Vapour Pressure |
0.0±4.9 mmHg at 25°C
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| Index of Refraction |
1.656
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| LogP |
-2.84
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| Hydrogen Bond Donor Count |
8
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| Hydrogen Bond Acceptor Count |
11
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| Rotatable Bond Count |
4
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| Heavy Atom Count |
23
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| Complexity |
395
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| Defined Atom Stereocenter Count |
8
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| SMILES |
C1[C@H]([C@H]([C@@H](C(O1)(CO)O)O[C@@H]2[C@@H]([C@H]([C@@H]([C@H](O2)CO)O)O)O)O)O
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| InChi Key |
SEWFWJUQVJHATO-PUVWEJBASA-N
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| InChi Code |
InChI=1S/C12H22O11/c13-1-5-7(17)8(18)9(19)11(22-5)23-10-6(16)4(15)2-21-12(10,20)3-14/h4-11,13-20H,1-3H2/t4-,5-,6-,7-,8+,9-,10+,11-,12?/m1/s1
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| Chemical Name |
(3S,4R,5R)-2-(hydroxymethyl)-3-[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyoxane-2,4,5-triol
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| HS Tariff Code |
2934.99.9001
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| Storage |
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month Note: Please store this product in a sealed and protected environment (e.g. under nitrogen), avoid exposure to moisture and light. |
| Shipping Condition |
Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)
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| Solubility (In Vitro) |
H2O : ≥ 130 mg/mL (~379.78 mM)
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|---|---|
| Solubility (In Vivo) |
Solubility in Formulation 1: 100 mg/mL (292.14 mM) in PBS (add these co-solvents sequentially from left to right, and one by one), clear solution; with sonication.
(Please use freshly prepared in vivo formulations for optimal results.) |
| Preparing Stock Solutions | 1 mg | 5 mg | 10 mg | |
| 1 mM | 2.9214 mL | 14.6071 mL | 29.2141 mL | |
| 5 mM | 0.5843 mL | 2.9214 mL | 5.8428 mL | |
| 10 mM | 0.2921 mL | 1.4607 mL | 2.9214 mL |
*Note: Please select an appropriate solvent for the preparation of stock solution based on your experiment needs. For most products, DMSO can be used for preparing stock solutions (e.g. 5 mM, 10 mM, or 20 mM concentration); some products with high aqueous solubility may be dissolved in water directly. Solubility information is available at the above Solubility Data section. Once the stock solution is prepared, aliquot it to routine usage volumes and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles.
Calculation results
Working concentration： mg/mL；
Method for preparing DMSO stock solution： mg drug pre-dissolved in μL DMSO (stock solution concentration mg/mL). Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:：Take μL DMSO stock solution, next add μL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O，mix and clarify.
(1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
(2) Be sure to add the solvent(s) in order.
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