| Size | Price | Stock | Qty |
|---|---|---|---|
| 5mg |
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| 10mg |
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| Other Sizes |
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| Targets |
Aldose-reductase (IC50 = 6.2 μM)
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|---|---|
| ln Vitro |
The first contribution summarizes current trends in research on medicinal plants in Mexico with emphasis on work carried out at the authors' laboratories. The most relevant phytochemical and pharmacological profiles of a selected group of plants used widely for treating major national health problems are described. The second contribution provides a detailed survey of the so far reported literature data on the capacities of selected oxyprenylated phenylpropanoids and polyketides to trigger receptors, enzymes, and other types of cellular factors for which they exhibit a high degree of affinity and therefore evoke specifice responses. And the third contribution discusses aspects of endophytic actinobacterial biology and chemistry, including biosynthesis and total synthesis of secondary metabolites produced in culture. It also presents perspectives fo the future of microbial biodiscovery, with emphasis on the seondary metabolism of endophytic actinobacteria [1].
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| References | |
| Additional Infomation |
Mukurozidiol is a member of psoralens.
(Rac)-Byakangelicin has been reported in Heracleum moellendorffii var. paucivittatum, Thamnosma rhodesica, and other organisms with data available. See also: Byakangelicin (annotation moved to). |
| Molecular Formula |
C17H18O7
|
|---|---|
| Molecular Weight |
334.31
|
| Exact Mass |
334.105
|
| CAS # |
19573-01-4
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| Related CAS # |
Byakangelicin;482-25-7
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| PubChem CID |
616063
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| Appearance |
Off-white to light yellow solid powder
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| Density |
1.4±0.1 g/cm3
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| Boiling Point |
571.5±50.0 °C at 760 mmHg
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| Melting Point |
117 - 118 °C
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| Flash Point |
299.4±30.1 °C
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| Vapour Pressure |
0.0±1.7 mmHg at 25°C
|
| Index of Refraction |
1.613
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| LogP |
1.62
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| Hydrogen Bond Donor Count |
2
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| Hydrogen Bond Acceptor Count |
7
|
| Rotatable Bond Count |
5
|
| Heavy Atom Count |
24
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| Complexity |
503
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| Defined Atom Stereocenter Count |
0
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| InChi Key |
PKRPFNXROFUNDE-UHFFFAOYSA-N
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| InChi Code |
InChI=1S/C17H18O7/c1-17(2,20)11(18)8-23-16-14-10(6-7-22-14)13(21-3)9-4-5-12(19)24-15(9)16/h4-7,11,18,20H,8H2,1-3H3
|
| Chemical Name |
9-(2,3-dihydroxy-3-methylbutoxy)-4-methoxyfuro[3,2-g]chromen-7-one
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| Synonyms |
(Rac)-Byakangelicin; 19573-01-4; Byakangellicin; Mukurozidiol; 9-(2,3-dihydroxy-3-methylbutoxy)-4-methoxyfuro[3,2-g]chromen-7-one; AC1LDCJL; (Rac)-Byakangelicin (Standard);
|
| HS Tariff Code |
2934.99.9001
|
| Storage |
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month |
| Shipping Condition |
Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)
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| Solubility (In Vitro) |
DMSO : ~100 mg/mL (~299.11 mM)
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|---|---|
| Solubility (In Vivo) |
Solubility in Formulation 1: ≥ 2.5 mg/mL (7.48 mM) (saturation unknown) in 10% DMSO + 90% Corn Oil (add these co-solvents sequentially from left to right, and one by one), clear solution.
For example, if 1 mL of working solution is to be prepared, you can add 100 μL of 25.0 mg/mL clear DMSO stock solution to 900 μL of corn oil and mix evenly. (Please use freshly prepared in vivo formulations for optimal results.) |
| Preparing Stock Solutions | 1 mg | 5 mg | 10 mg | |
| 1 mM | 2.9912 mL | 14.9562 mL | 29.9124 mL | |
| 5 mM | 0.5982 mL | 2.9912 mL | 5.9825 mL | |
| 10 mM | 0.2991 mL | 1.4956 mL | 2.9912 mL |
*Note: Please select an appropriate solvent for the preparation of stock solution based on your experiment needs. For most products, DMSO can be used for preparing stock solutions (e.g. 5 mM, 10 mM, or 20 mM concentration); some products with high aqueous solubility may be dissolved in water directly. Solubility information is available at the above Solubility Data section. Once the stock solution is prepared, aliquot it to routine usage volumes and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles.
Calculation results
Working concentration： mg/mL；
Method for preparing DMSO stock solution： mg drug pre-dissolved in μL DMSO (stock solution concentration mg/mL). Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:：Take μL DMSO stock solution, next add μL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O，mix and clarify.
(1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
(2) Be sure to add the solvent(s) in order.
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