| Size | Price | Stock | Qty |
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| 100mg |
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| 250mg |
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| 500mg |
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| Other Sizes |
| Targets |
Quininic acid is an organic acid with no specific reported molecular target. It is a naturally occurring compound found in various plants and is used as a chemical intermediate and research reagent. Further pharmacological characterization is needed.
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|---|---|
| ln Vitro |
Quinic acid is the most prevalent organic acid, making up, on average, 86.3% of all organic acids. Quinic acid is a useful astringent and a raw material for the creation of novel pharmaceuticals [1].
Specific in vitro activities of quininic acid are not extensively reported in the available literature. As a naturally occurring organic acid, it may have general biological effects, but detailed pharmacological data are limited. Further research is needed to characterize its activity. |
| ln Vivo |
In vivo biological activities of quininic acid are not extensively documented in the available literature. The compound is primarily used as a research chemical and analytical standard rather than a pharmacologically active agent.
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| Enzyme Assay |
Standard in vitro assays for quininic acid would depend on the specific application. As a research chemical, the compound may be used in analytical chemistry applications such as chromatography or as a reference standard for quantification.
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| Cell Assay |
Cell-based assays for quininic acid are not extensively reported in the available literature. The compound is primarily used as a research reagent and chemical intermediate rather than for cell-based pharmacological studies.
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| Animal Protocol |
In vivo studies for quininic acid are not extensively documented in the available literature. The compound is not a pharmacologically active drug but rather a naturally occurring organic acid and research chemical.
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| ADME/Pharmacokinetics |
Pharmacokinetic properties of quininic acid are not extensively reported in the available literature. As a naturally occurring compound, its metabolism and disposition in biological systems would depend on the specific context of its use.
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| Toxicity/Toxicokinetics |
Toxicity data for quininic acid are not extensively detailed in the available literature. The compound is naturally occurring and is used as a research chemical. Standard safety precautions should be followed when handling the compound in the laboratory.
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| References | |
| Additional Infomation |
Reports indicate that velvetleaf contains quinic acid, and relevant data is available for reference.
Quininic acid is a naturally occurring organic acid found in eucalyptus, cinchona bark, and other plant products. It is used as a research chemical, analytical standard, and chemical intermediate. The compound is not a pharmaceutical drug and has no approved clinical indications. |
| Molecular Formula |
C11H9NO3
|
|---|---|
| Molecular Weight |
203.1941
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| Exact Mass |
203.058
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| CAS # |
86-68-0
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| PubChem CID |
345824
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| Appearance |
White to yellow solid powder
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| Density |
1.325 g/cm3
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| Boiling Point |
385.4ºC at
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| Melting Point |
280 °C(dec.)
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| Flash Point |
186.9ºC
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| Index of Refraction |
1.648
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| LogP |
1.941
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| Hydrogen Bond Donor Count |
1
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| Hydrogen Bond Acceptor Count |
4
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| Rotatable Bond Count |
2
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| Heavy Atom Count |
15
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| Complexity |
244
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| Defined Atom Stereocenter Count |
0
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| InChi Key |
XXLFLUJXWKXUGS-UHFFFAOYSA-N
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| InChi Code |
InChI=1S/C11H9NO3/c1-15-7-2-3-10-9(6-7)8(11(13)14)4-5-12-10/h2-6H,1H3,(H,13,14)
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| Chemical Name |
6-methoxyquinoline-4-carboxylic acid
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| HS Tariff Code |
2934.99.9001
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| Storage |
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month |
| Shipping Condition |
Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)
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| Solubility (In Vitro) |
DMSO : ~16.67 mg/mL (~82.04 mM)
|
|---|---|
| Solubility (In Vivo) |
Solubility in Formulation 1: ≥ 1.67 mg/mL (8.22 mM) (saturation unknown) in 10% DMSO + 40% PEG300 + 5% Tween80 + 45% Saline (add these co-solvents sequentially from left to right, and one by one), clear solution.
For example, if 1 mL of working solution is to be prepared, you can add 100 μL of 16.7 mg/mL clear DMSO stock solution to 400 μL PEG300 and mix evenly; then add 50 μL Tween-80 to the above solution and mix evenly; then add 450 μL normal saline to adjust the volume to 1 mL. Preparation of saline: Dissolve 0.9 g of sodium chloride in 100 mL ddH₂ O to obtain a clear solution. Solubility in Formulation 2: ≥ 1.67 mg/mL (8.22 mM) (saturation unknown) in 10% DMSO + 90% Corn Oil (add these co-solvents sequentially from left to right, and one by one), clear solution. For example, if 1 mL of working solution is to be prepared, you can add 100 μL of 16.7 mg/mL clear DMSO stock solution to 900 μL of corn oil and mix evenly. (Please use freshly prepared in vivo formulations for optimal results.) |
| Preparing Stock Solutions | 1 mg | 5 mg | 10 mg | |
| 1 mM | 4.9215 mL | 24.6075 mL | 49.2150 mL | |
| 5 mM | 0.9843 mL | 4.9215 mL | 9.8430 mL | |
| 10 mM | 0.4922 mL | 2.4608 mL | 4.9215 mL |
*Note: Please select an appropriate solvent for the preparation of stock solution based on your experiment needs. For most products, DMSO can be used for preparing stock solutions (e.g. 5 mM, 10 mM, or 20 mM concentration); some products with high aqueous solubility may be dissolved in water directly. Solubility information is available at the above Solubility Data section. Once the stock solution is prepared, aliquot it to routine usage volumes and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles.
Calculation results
Working concentration： mg/mL；
Method for preparing DMSO stock solution： mg drug pre-dissolved in μL DMSO (stock solution concentration mg/mL). Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:：Take μL DMSO stock solution, next add μL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O，mix and clarify.
(1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
(2) Be sure to add the solvent(s) in order.
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