| Size | Price | Stock | Qty |
|---|---|---|---|
| 50mg |
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| 100mg |
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| Other Sizes |
| Targets |
2-Aminopyrimidin-5-ol does not have a well-characterized specific biological target. As an endogenous metabolite, it may be involved in pyrimidine metabolism. Pyrimidines are essential components of nucleic acids and are involved in various cellular processes. Further studies are needed to elucidate the specific molecular targets and biological functions of this compound.
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|---|---|
| ln Vitro |
In vitro studies of 2-Aminopyrimidin-5-ol are limited. As an organic synthesis building block, it is used in the preparation of various chemical compounds. The compound may be used in studies of pyrimidine metabolism and as a reference standard in metabolomics research. Further research is needed to characterize its in vitro biological activity.
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| ln Vivo |
In vivo activity data for 2-Aminopyrimidin-5-ol are limited. As an endogenous metabolite, it is produced in the body and may be involved in pyrimidine metabolism. Further research is needed to evaluate its in vivo biological functions and potential therapeutic applications.
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| Enzyme Assay |
In vitro enzyme/receptor binding assays for 2-Aminopyrimidin-5-ol are not well-established. As a pyrimidine derivative, it may interact with enzymes involved in pyrimidine metabolism. Further research is needed to develop specific assays for studying the molecular interactions of this compound with enzymes and other biomolecules.
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| Cell Assay |
In vitro cell-based assays for 2-Aminopyrimidin-5-ol are not well-established. As a metabolite, it may be studied in cell lines for its effects on pyrimidine metabolism. Further research is needed to characterize its effects on various cell types and to identify its mechanism of action.
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| ADME/Pharmacokinetics |
2-Aminopyrimidin-5-ol has a molecular formula of C4H5N3O and a molecular weight of 111.10. The CAS number is 143489-45-6. The compound has a purity of 97%. It is a pyrimidine derivative. The compound is intended for research use only.
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| Toxicity/Toxicokinetics |
The toxicity profile of 2-Aminopyrimidin-5-ol is not extensively characterized, as it is an endogenous metabolite. It is generally considered safe for use in biochemical research. The compound is intended for research use only and is not approved for therapeutic use in humans. Standard laboratory safety practices should be followed when handling this compound.
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| Additional Infomation |
2-Amino-5-hydroxypyrimidine is a hydroxypyrimidine.
2-Aminopyrimidin-5-ol (CAS 143489-45-6), also known as 2-Amino-5-hydroxypyrimidine, is an endogenously produced metabolite. It is a hydroxypyrimidine compound useful in organic synthesis. It has a molecular formula of C4H5N3O and a molecular weight of 111.10. The compound is intended for research use only. |
| Molecular Formula |
C4H5N3O
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|---|---|
| Molecular Weight |
111.10
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| Exact Mass |
111.043
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| CAS # |
143489-45-6
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| PubChem CID |
17750388
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| Appearance |
Solid powder
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| Density |
1.5±0.1 g/cm3
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| Boiling Point |
393.6±34.0 °C at 760 mmHg
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| Melting Point |
>170ºC (dec.)
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| Flash Point |
191.9±25.7 °C
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| Vapour Pressure |
0.0±0.9 mmHg at 25°C
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| Index of Refraction |
1.668
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| LogP |
0.09
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| Hydrogen Bond Donor Count |
2
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| Hydrogen Bond Acceptor Count |
4
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| Rotatable Bond Count |
0
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| Heavy Atom Count |
8
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| Complexity |
69.7
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| Defined Atom Stereocenter Count |
0
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| SMILES |
C1=C(C=NC(=N1)N)O
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| InChi Key |
NVYMOVCPYONOSF-UHFFFAOYSA-N
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| InChi Code |
InChI=1S/C4H5N3O/c5-4-6-1-3(8)2-7-4/h1-2,8H,(H2,5,6,7)
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| Chemical Name |
2-aminopyrimidin-5-ol
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| HS Tariff Code |
2934.99.9001
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| Storage |
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month Note: This product requires protection from light (avoid light exposure) during transportation and storage. |
| Shipping Condition |
Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)
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| Solubility (In Vitro) |
DMSO :~125 mg/mL (~1125.11 mM)
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|---|---|
| Solubility (In Vivo) |
Solubility in Formulation 1: ≥ 2.08 mg/mL (18.72 mM) (saturation unknown) in 10% DMSO + 90% (20% SBE-β-CD in Saline) (add these co-solvents sequentially from left to right, and one by one), clear solution.
For example, if 1 mL of working solution is to be prepared, you can add 100 μL of 20.8 mg/mL clear DMSO stock solution to 900 μL of 20% SBE-β-CD physiological saline solution and mix evenly. Preparation of 20% SBE-β-CD in Saline (4°C，1 week): Dissolve 2 g SBE-β-CD in 10 mL saline to obtain a clear solution. (Please use freshly prepared in vivo formulations for optimal results.) |
| Preparing Stock Solutions | 1 mg | 5 mg | 10 mg | |
| 1 mM | 9.0009 mL | 45.0045 mL | 90.0090 mL | |
| 5 mM | 1.8002 mL | 9.0009 mL | 18.0018 mL | |
| 10 mM | 0.9001 mL | 4.5005 mL | 9.0009 mL |
*Note: Please select an appropriate solvent for the preparation of stock solution based on your experiment needs. For most products, DMSO can be used for preparing stock solutions (e.g. 5 mM, 10 mM, or 20 mM concentration); some products with high aqueous solubility may be dissolved in water directly. Solubility information is available at the above Solubility Data section. Once the stock solution is prepared, aliquot it to routine usage volumes and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles.
Calculation results
Working concentration： mg/mL；
Method for preparing DMSO stock solution： mg drug pre-dissolved in μL DMSO (stock solution concentration mg/mL). Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:：Take μL DMSO stock solution, next add μL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O，mix and clarify.
(1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
(2) Be sure to add the solvent(s) in order.
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