| Size | Price | Stock | Qty |
|---|---|---|---|
| 1g |
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| Other Sizes |
| Targets |
Mesoxalate sodium monohydrate does not have a specific pharmacological target as it is an endogenous metabolite and research chemical. As a dicarboxylic acid derivative, it is involved in organic acid metabolism. Its "target" in research is the study of enzymatic reactions involving dicarboxylic acids and links between altered organic acid metabolism and disease.
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|---|---|
| ln Vitro |
In vitro, Mesoxalate sodium monohydrate is used as a tool for probing enzymatic reactions involving dicarboxylic acids. It is an endogenously produced metabolite. Its "activity" is reflected in its chemical properties as a dicarboxylic acid derivative and its role in metabolic studies.
|
| ln Vivo |
In vivo, Mesoxalate sodium monohydrate is an endogenously produced metabolite. It is not a therapeutic agent but is studied in the context of organic acid metabolism and disease. Its levels in biological samples may reflect metabolic activity or alterations in disease states.
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| Enzyme Assay |
In vitro enzyme assays with Mesoxalate sodium monohydrate typically involve studying enzymes that recognize dicarboxylic acids. The compound can be used as a substrate or inhibitor in assays to characterize enzyme activity. Standard assays involve incubating with enzyme preparations and analyzing products by chromatographic methods.
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| Cell Assay |
Mesoxalate sodium monohydrate is not typically used in cell culture experiments as a bioactive compound for treating cells. However, it may be employed in studies investigating organic acid metabolism or mitochondrial dysfunction. Its primary use is as a research chemical for probing enzymatic reactions.
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| Animal Protocol |
In vivo animal experiments with Mesoxalate sodium monohydrate are not commonly performed as the compound is an endogenous metabolite and research chemical. If used, it would be to study organic acid metabolism or mitochondrial dysfunction. Its primary significance is in research as a tool for studying dicarboxylic acid metabolism.
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| ADME/Pharmacokinetics |
The pharmacokinetic (PK) properties of Mesoxalate sodium monohydrate are not characterized as the compound is a metabolite rather than a drug. As a small, polar molecule, it is expected to be readily excreted. Specific PK data are not available in the literature.
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| Toxicity/Toxicokinetics |
Mesoxalate sodium monohydrate has a low toxicity profile as an endogenous metabolite. For research use, standard laboratory safety practices are sufficient. It is not considered a hazardous substance. Comprehensive toxicology studies have not been published for this compound.
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| Additional Infomation |
Mesoxalate sodium monohydrate (Sodium mesoxalate monohydrate) is an endogenously produced metabolite. It is a useful tool for probing enzymatic reactions involving dicarboxylic acids and for exploring links between altered organic acid metabolism and disease, including metabolic syndromes and mitochondrial dysfunction. The compound is not a drug and has no therapeutic indications.
|
| Molecular Formula |
C3H2NA2O6
|
|---|---|
| Molecular Weight |
180.02
|
| Exact Mass |
179.965
|
| CAS # |
31635-99-1
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| PubChem CID |
6097181
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| Appearance |
White to off-white solid powder
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| Density |
2.181g/cm3
|
| Boiling Point |
474ºC at 760mmHg
|
| Flash Point |
254.6ºC
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| Hydrogen Bond Donor Count |
2
|
| Hydrogen Bond Acceptor Count |
6
|
| Rotatable Bond Count |
0
|
| Heavy Atom Count |
11
|
| Complexity |
119
|
| Defined Atom Stereocenter Count |
0
|
| InChi Key |
HMBGDJCPFGQLIO-UHFFFAOYSA-L
|
| InChi Code |
InChI=1S/C3H4O6.2Na/c4-1(5)3(8,9)2(6)7;;/h8-9H,(H,4,5)(H,6,7);;/q;2*+1/p-2
|
| Chemical Name |
disodium;2,2-dihydroxypropanedioate
|
| HS Tariff Code |
2934.99.9001
|
| Storage |
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month Note: Please store this product in a sealed and protected environment, avoid exposure to moisture. |
| Shipping Condition |
Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)
|
| Solubility (In Vitro) |
H2O: 30 mg/mL (166.65 mM)
|
|---|---|
| Solubility (In Vivo) |
Solubility in Formulation 1: 6.67 mg/mL (37.05 mM) in PBS (add these co-solvents sequentially from left to right, and one by one), clear solution; with sonication.
(Please use freshly prepared in vivo formulations for optimal results.) |
| Preparing Stock Solutions | 1 mg | 5 mg | 10 mg | |
| 1 mM | 5.5549 mL | 27.7747 mL | 55.5494 mL | |
| 5 mM | 1.1110 mL | 5.5549 mL | 11.1099 mL | |
| 10 mM | 0.5555 mL | 2.7775 mL | 5.5549 mL |
*Note: Please select an appropriate solvent for the preparation of stock solution based on your experiment needs. For most products, DMSO can be used for preparing stock solutions (e.g. 5 mM, 10 mM, or 20 mM concentration); some products with high aqueous solubility may be dissolved in water directly. Solubility information is available at the above Solubility Data section. Once the stock solution is prepared, aliquot it to routine usage volumes and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles.
Calculation results
Working concentration： mg/mL；
Method for preparing DMSO stock solution： mg drug pre-dissolved in μL DMSO (stock solution concentration mg/mL). Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:：Take μL DMSO stock solution, next add μL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O，mix and clarify.
(1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
(2) Be sure to add the solvent(s) in order.
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