| Size | Price | |
|---|---|---|
| Other Sizes |
| Targets |
D-Lyxose does not have a specific pharmacological target as it is a monosaccharide used in research. It is used in molecular modeling calculations in the study of drug binding and recognition in relation to aldose reductase. Its "target" in research is the study of carbohydrate chemistry and drug interactions.
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|---|---|
| ln Vitro |
In vitro, D-Lyxose is used as a monosaccharide in biochemical research. It is a reducing carbohydrate and is used in molecular modeling calculations to study drug binding and recognition in relation to aldose reductase. Its "activity" is reflected in its chemical properties as a sugar.
|
| ln Vivo |
In vivo, D-Lyxose is not a therapeutic agent. It is a monosaccharide present in maple syrup. It is a non-natural substance that can be produced synthetically. It is used in research to study carbohydrate metabolism and drug binding.
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| Enzyme Assay |
In vitro enzyme assays with D-Lyxose typically involve studying aldose reductase or other carbohydrate-metabolizing enzymes. The compound is used as a substrate or inhibitor in assays to characterize enzyme activity. Standard assays involve incubating with enzyme preparations and measuring products by spectrophotometric or chromatographic methods.
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| Cell Assay |
D-Lyxose is not typically used in cell culture experiments as a bioactive compound for treating cells. However, it may be employed in studies investigating carbohydrate metabolism or as a sugar source in defined media. Its primary use is as a research chemical.
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| Animal Protocol |
In vivo animal experiments with D-Lyxose are not commonly performed as the compound is a research chemical. If used, it would be to study carbohydrate metabolism or drug binding in animal models. Its primary significance is in research as a monosaccharide for biochemical studies.
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| ADME/Pharmacokinetics |
The pharmacokinetic (PK) properties of D-Lyxose are not well characterized. As a small monosaccharide, it is expected to be absorbed and metabolized. It has a melting point of 108-112°C and a density of 1.545. It is stored in a refrigerator.
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| Toxicity/Toxicokinetics |
D-Lyxose has a low toxicity profile as a monosaccharide. For research use, standard laboratory safety practices are sufficient. It is not considered a hazardous substance. Comprehensive toxicology studies have not been published for this compound.
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| Additional Infomation |
2,3,4,5-Tetrahydroxypentanal is a pentose, polyol, and hydroxy aldehyde. DL-arabinose has been reported in Arabidopsis thaliana, Streptomyces hainanense, and other organisms with relevant data. Pectin is a high-molecular-weight polysaccharide found in the cell walls of all plants. Pectin binds cell walls together. It is used in the food industry as an emulsifier and stabilizer. Pectin has been attempted for various therapeutic uses, including as an antidiarrheal (but is now generally considered ineffective) and for treating hypercholesterolemia. See also: Citrus pectin (note moved to); Pectin (note moved to); L-arabinose (note moved to)... See more...
D-Lyxose is a monosaccharide and a C'-2 epimer of D-Xylose. It is a reducing carbohydrate present in maple syrup. It is used in molecular modeling calculations in the study of drug binding and recognition in relation to aldose reductase. The compound is not a drug and has no therapeutic indications. It is available for laboratory research use only. |
| Molecular Formula |
C5H10O5
|
|---|---|
| Molecular Weight |
150.13
|
| Exact Mass |
150.052
|
| CAS # |
1114-34-7
|
| Related CAS # |
D-Lyxose-13C-2;70849-22-8;D-Lyxose-13C-3;83379-39-9;D-Lyxose-13C-4;139657-61-7;D-Lyxose-d;288846-88-8;D-Lyxose-d-1
|
| PubChem CID |
854
|
| Appearance |
White to off-white solid powder
|
| Density |
1.8±0.1 g/cm3
|
| Boiling Point |
333.2±42.0 °C at 760 mmHg
|
| Melting Point |
108-112ºC(lit.)
|
| Flash Point |
155.3±27.9 °C
|
| Vapour Pressure |
0.0±1.6 mmHg at 25°C
|
| Index of Refraction |
1.646
|
| LogP |
-0.83
|
| Hydrogen Bond Donor Count |
4
|
| Hydrogen Bond Acceptor Count |
5
|
| Rotatable Bond Count |
4
|
| Heavy Atom Count |
10
|
| Complexity |
104
|
| Defined Atom Stereocenter Count |
0
|
| SMILES |
C1[C@H]([C@@H]([C@@H](C(O1)O)O)O)O
|
| InChi Key |
PYMYPHUHKUWMLA-UHFFFAOYSA-N
|
| InChi Code |
InChI=1S/C5H10O5/c6-1-3(8)5(10)4(9)2-7/h1,3-5,7-10H,2H2
|
| Chemical Name |
2,3,4,5-tetrahydroxypentanal
|
| HS Tariff Code |
2934.99.9001
|
| Storage |
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month |
| Shipping Condition |
Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)
|
| Solubility (In Vitro) |
H2O: 250 mg/mL (1665.22 mM)
|
|---|---|
| Solubility (In Vivo) |
Solubility in Formulation 1: 50 mg/mL (333.04 mM) in PBS (add these co-solvents sequentially from left to right, and one by one), clear solution; with sonication.
(Please use freshly prepared in vivo formulations for optimal results.) |
| Preparing Stock Solutions | 1 mg | 5 mg | 10 mg | |
| 1 mM | 6.6609 mL | 33.3045 mL | 66.6089 mL | |
| 5 mM | 1.3322 mL | 6.6609 mL | 13.3218 mL | |
| 10 mM | 0.6661 mL | 3.3304 mL | 6.6609 mL |
*Note: Please select an appropriate solvent for the preparation of stock solution based on your experiment needs. For most products, DMSO can be used for preparing stock solutions (e.g. 5 mM, 10 mM, or 20 mM concentration); some products with high aqueous solubility may be dissolved in water directly. Solubility information is available at the above Solubility Data section. Once the stock solution is prepared, aliquot it to routine usage volumes and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles.
Calculation results
Working concentration： mg/mL；
Method for preparing DMSO stock solution： mg drug pre-dissolved in μL DMSO (stock solution concentration mg/mL). Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:：Take μL DMSO stock solution, next add μL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O，mix and clarify.
(1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
(2) Be sure to add the solvent(s) in order.
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