| Size | Price | Stock | Qty |
|---|---|---|---|
| 1g |
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| Other Sizes |
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| Targets |
Microbial Metabolite Human Endogenous Metabolite
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|---|---|
| References | |
| Additional Infomation |
D-proline is the D-enantiomer of proline. It has a role as a mouse metabolite. It is a D-alpha-amino acid and a proline. It is a conjugate base of a D-prolinium. It is a conjugate acid of a D-prolinate. It is an enantiomer of a L-proline. It is a tautomer of a D-proline zwitterion.
D-proline is an isomer of the naturally occurring amino acid, L-Proline. D-amino acids have been found in relatively high abundance in human plasma and saliva. These amino acids may be of bacterial origin, but there is also evidence that they are endogenously produced through amino acid racemase activity. D-proline has been reported in Antirrhinum majus, Homo sapiens, and other organisms with data available. See also: Proline (annotation moved to). Pharmacodynamics L-Proline is a major amino acid found in cartilage and is important for maintaining youthful skin as well as repair of muscle, connective tissue and skin damage. It is also essential for the immune system, and for necessary balance of this formula. It is an essential component of collagen and is important for proper functioning of joints and tendons. L-Proline is extremely important for the proper functioning of joints and tendons. Helps maintain and strengthen heart muscles. |
| Molecular Formula |
C5H9NO2
|
|---|---|
| Molecular Weight |
115.13
|
| Exact Mass |
115.063
|
| CAS # |
344-25-2
|
| Related CAS # |
L-Proline;147-85-3;(R)-Pyrrolidine-2-carboxylic acid-d3;1994265-09-6
|
| PubChem CID |
8988
|
| Appearance |
White to off-white solid powder
|
| Density |
1.2±0.1 g/cm3
|
| Boiling Point |
252.2±33.0 °C at 760 mmHg
|
| Melting Point |
223ºC
|
| Flash Point |
106.3±25.4 °C
|
| Vapour Pressure |
0.0±1.1 mmHg at 25°C
|
| Index of Refraction |
1.487
|
| LogP |
-0.57
|
| Hydrogen Bond Donor Count |
2
|
| Hydrogen Bond Acceptor Count |
3
|
| Rotatable Bond Count |
1
|
| Heavy Atom Count |
8
|
| Complexity |
103
|
| Defined Atom Stereocenter Count |
1
|
| SMILES |
C1C[C@@H](NC1)C(=O)O
|
| InChi Key |
ONIBWKKTOPOVIA-SCSAIBSYSA-N
|
| InChi Code |
InChI=1S/C5H9NO2/c7-5(8)4-2-1-3-6-4/h4,6H,1-3H2,(H,7,8)/t4-/m1/s1
|
| Chemical Name |
(2R)-pyrrolidine-2-carboxylic acid
|
| HS Tariff Code |
2934.99.9001
|
| Storage |
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month |
| Shipping Condition |
Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)
|
| Solubility (In Vitro) |
H2O: 25 mg/mL (217.15 mM)
DMSO: 2.78 mg/mL (24.15 mM) |
|---|---|
| Solubility (In Vivo) |
Solubility in Formulation 1: 12.5 mg/mL (108.57 mM) in PBS (add these co-solvents sequentially from left to right, and one by one), clear solution; with sonication.
(Please use freshly prepared in vivo formulations for optimal results.) |
| Preparing Stock Solutions | 1 mg | 5 mg | 10 mg | |
| 1 mM | 8.6858 mL | 43.4292 mL | 86.8583 mL | |
| 5 mM | 1.7372 mL | 8.6858 mL | 17.3717 mL | |
| 10 mM | 0.8686 mL | 4.3429 mL | 8.6858 mL |
*Note: Please select an appropriate solvent for the preparation of stock solution based on your experiment needs. For most products, DMSO can be used for preparing stock solutions (e.g. 5 mM, 10 mM, or 20 mM concentration); some products with high aqueous solubility may be dissolved in water directly. Solubility information is available at the above Solubility Data section. Once the stock solution is prepared, aliquot it to routine usage volumes and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles.
Calculation results
Working concentration： mg/mL；
Method for preparing DMSO stock solution： mg drug pre-dissolved in μL DMSO (stock solution concentration mg/mL). Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:：Take μL DMSO stock solution, next add μL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O，mix and clarify.
(1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
(2) Be sure to add the solvent(s) in order.
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