| Size | Price | Stock | Qty |
|---|---|---|---|
| 50g |
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| 100g |
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| Other Sizes |
| Targets |
Tetrabutylammonium perchlorate does not have a defined pharmacological target. It is a supporting electrolyte used in non-aqueous electrochemical systems. Its mechanism of action is physical: it provides a conductive medium with a wide electrochemical window, enabling accurate redox measurements across a broad potential range.
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|---|---|
| ln Vitro |
In vitro, tetrabutylammonium perchlorate is used as a supporting electrolyte in various electrochemical applications, enhancing conductivity and stability in solutions. It is used in polarographic measurements, cyclic voltammetry, and organic electrosynthesis. It is also used as an ion-pairing reagent in analytical chemistry and as a reagent in organic synthesis and materials research.
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| ln Vivo |
In vivo activity data for tetrabutylammonium perchlorate are not available, as the compound is a chemical reagent used for in vitro applications. It is not intended for in vivo administration and has no established in vivo pharmacokinetic or pharmacodynamic profile.
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| Enzyme Assay |
For in vitro electrochemical experiments, tetrabutylammonium perchlorate is used as a supporting electrolyte. Standard protocols involve dissolving the compound in an appropriate organic solvent (e.g., acetonitrile, dichloromethane) at a concentration of 0.1-1.0 M. The resulting solution is used as the electrolyte medium for electrochemical measurements such as cyclic voltammetry or polarography.
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| Cell Assay |
For in vitro cell-based experiments, tetrabutylammonium perchlorate is not typically used directly in cell culture. It is a chemical reagent used for electrochemical and analytical applications. The compound may be used in the synthesis of compounds that are subsequently tested in cell-based assays.
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| Animal Protocol |
In vivo animal studies for tetrabutylammonium perchlorate are not applicable, as the compound is a chemical reagent used for in vitro applications. No animal studies have been conducted for this compound as a therapeutic agent.
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| ADME/Pharmacokinetics |
Pharmacokinetic data for tetrabutylammonium perchlorate are not available, as the compound is not a drug and is not administered to living organisms. It is soluble in common organic solvents, making it suitable for electrochemical electrolytes.
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| Toxicity/Toxicokinetics |
Tetrabutylammonium perchlorate is a research chemical and should be handled with appropriate laboratory safety precautions. As a perchlorate salt, it may be explosive and should be handled with care. The compound is for research use only and not for human therapeutic or diagnostic applications.
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| Additional Infomation |
Tetrabutylammonium perchlorate (TBAP) (CAS 1923-70-2) is primarily a research-grade chemical reagent, not an FDA-approved pharmaceutical drug. Its primary applications are as a supporting electrolyte in electrochemical applications, as an ion-pairing reagent in analytical chemistry, and as a reagent in organic synthesis.
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| Molecular Formula |
C16H36CLNO4
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|---|---|
| Molecular Weight |
341.91
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| Exact Mass |
341.233
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| CAS # |
1923-70-2
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| Related CAS # |
10549-76-5 (Parent)
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| PubChem CID |
74723
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| Appearance |
White to off-white solid powder
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| Melting Point |
211-215 °C
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| LogP |
5.217
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| Hydrogen Bond Donor Count |
0
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| Hydrogen Bond Acceptor Count |
4
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| Rotatable Bond Count |
12
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| Heavy Atom Count |
22
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| Complexity |
212
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| Defined Atom Stereocenter Count |
0
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| SMILES |
Cl(=O)(=O)(=O)[O-].[N+](C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])(C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])(C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
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| InChi Key |
KBLZDCFTQSIIOH-UHFFFAOYSA-M
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| InChi Code |
InChI=1S/C16H36N.ClHO4/c1-5-9-13-17(14-10-6-2,15-11-7-3)16-12-8-4;2-1(3,4)5/h5-16H2,1-4H3;(H,2,3,4,5)/q+1;/p-1
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| Chemical Name |
tetrabutylazanium;perchlorate
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| HS Tariff Code |
2934.99.9001
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| Storage |
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month Note: Please store this product in a sealed and protected environment, avoid exposure to moisture. |
| Shipping Condition |
Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)
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| Solubility (In Vitro) |
DMSO: 100 mg/mL (292.47 mM)
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|---|---|
| Solubility (In Vivo) |
Solubility in Formulation 1: ≥ 2.5 mg/mL (7.31 mM) (saturation unknown) in 10% DMSO + 40% PEG300 + 5% Tween80 + 45% Saline (add these co-solvents sequentially from left to right, and one by one), clear solution.
For example, if 1 mL of working solution is to be prepared, you can add 100 μL of 25.0 mg/mL clear DMSO stock solution to 400 μL PEG300 and mix evenly; then add 50 μL Tween-80 to the above solution and mix evenly; then add 450 μL normal saline to adjust the volume to 1 mL. Preparation of saline: Dissolve 0.9 g of sodium chloride in 100 mL ddH₂ O to obtain a clear solution. Solubility in Formulation 2: ≥ 2.5 mg/mL (7.31 mM) (saturation unknown) in 10% DMSO + 90% (20% SBE-β-CD in Saline) (add these co-solvents sequentially from left to right, and one by one), clear solution. For example, if 1 mL of working solution is to be prepared, you can add 100 μL of 25.0 mg/mL clear DMSO stock solution to 900 μL of 20% SBE-β-CD physiological saline solution and mix evenly. Preparation of 20% SBE-β-CD in Saline (4°C，1 week): Dissolve 2 g SBE-β-CD in 10 mL saline to obtain a clear solution. View More
Solubility in Formulation 3: ≥ 2.5 mg/mL (7.31 mM) (saturation unknown) in 10% DMSO + 90% Corn Oil (add these co-solvents sequentially from left to right, and one by one), clear solution. |
| Preparing Stock Solutions | 1 mg | 5 mg | 10 mg | |
| 1 mM | 2.9247 mL | 14.6237 mL | 29.2475 mL | |
| 5 mM | 0.5849 mL | 2.9247 mL | 5.8495 mL | |
| 10 mM | 0.2925 mL | 1.4624 mL | 2.9247 mL |
*Note: Please select an appropriate solvent for the preparation of stock solution based on your experiment needs. For most products, DMSO can be used for preparing stock solutions (e.g. 5 mM, 10 mM, or 20 mM concentration); some products with high aqueous solubility may be dissolved in water directly. Solubility information is available at the above Solubility Data section. Once the stock solution is prepared, aliquot it to routine usage volumes and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles.
Calculation results
Working concentration： mg/mL；
Method for preparing DMSO stock solution： mg drug pre-dissolved in μL DMSO (stock solution concentration mg/mL). Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:：Take μL DMSO stock solution, next add μL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O，mix and clarify.
(1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
(2) Be sure to add the solvent(s) in order.
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