| Size | Price | Stock | Qty |
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| 10mg |
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| 50mg |
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| 100mg |
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| Other Sizes |
| Targets |
As a fluorescent dye, 2,3-Di(furan-2-yl)quinoxaline does not target specific proteins or enzymes. Instead, it functions as a cell-permeable blue-fluorescent probe for cellular imaging applications. The presence of furan rings enhances its chemical properties and potential applications in organic synthesis and medicinal chemistry.
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| ln Vitro |
2,3-Di(furan-2-yl)quinoxaline is a quinoxaline derivative with blue fluorescence that is cell-permeable and sufficiently bright at micromolar concentrations (1.5 μM). The compound's blue fluorescence makes it suitable for cellular imaging applications. The presence of furan rings enhances its chemical properties and potential applications in various fields.
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| ln Vivo |
No significant in vivo activity data has been reported for 2,3-Di(furan-2-yl)quinoxaline as a therapeutic agent, as the compound is primarily utilized as a fluorescent probe for research applications. The compound is intended for research use only.
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| Enzyme Assay |
In vitro assays for 2,3-Di(furan-2-yl)quinoxaline typically involve measuring its fluorescence properties in various solvents and conditions. The compound's blue fluorescence can be characterized using fluorescence spectroscopy. The compound's cell permeability can be assessed using cellular uptake studies.
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| Cell Assay |
For in vitro cellular experiments, 2,3-Di(furan-2-yl)quinoxaline is dissolved in DMSO and diluted in cell culture medium. Cells are incubated with the compound at micromolar concentrations (1.5 μM) and analyzed by fluorescence microscopy. The compound's cell permeability enables efficient entry into live cells for imaging applications.
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| Animal Protocol |
In vivo animal experiments with 2,3-Di(furan-2-yl)quinoxaline are not typically performed, as the compound is primarily used as a fluorescent probe for in vitro cellular imaging. The compound is intended for research use only.
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| ADME/Pharmacokinetics |
Pharmacokinetic properties of 2,3-Di(furan-2-yl)quinoxaline have not been characterized, as the compound is a research-use fluorescent probe rather than a drug candidate. The compound has a molecular weight of 262.26 g/mol and a molecular formula of C₁₆H₁₀N₂O₂. It is soluble in DMSO at 100 mg/mL.
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| Toxicity/Toxicokinetics |
Toxicological data for 2,3-Di(furan-2-yl)quinoxaline has not been systematically evaluated, as the compound is intended for research applications only and not for therapeutic use. Standard laboratory safety precautions should be observed when handling this chemical reagent.
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| References | |
| Additional Infomation |
2,3-Di(furan-2-yl)quinoxaline (Compound 5) is a quinoxaline derivative with blue fluorescence that is cell-permeable and sufficiently bright at micromolar concentrations (1.5 μM). The presence of furan rings enhances its chemical properties and potential applications in organic synthesis and medicinal chemistry. The compound has no clinical or therapeutic applications and has not received regulatory approval.
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| Molecular Formula |
C16H10N2O2
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|---|---|
| Molecular Weight |
262.26
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| Exact Mass |
262.074
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| CAS # |
57490-73-0
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| PubChem CID |
236275
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| Appearance |
Light yellow to yellow solid powder
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| Density |
1.272g/cm3
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| Boiling Point |
360.5ºC at 760mmHg
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| Flash Point |
117.2ºC
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| Index of Refraction |
1.637
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| LogP |
4.149
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| Hydrogen Bond Donor Count |
0
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| Hydrogen Bond Acceptor Count |
4
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| Rotatable Bond Count |
2
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| Heavy Atom Count |
20
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| Complexity |
306
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| Defined Atom Stereocenter Count |
0
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| SMILES |
C1=CC=C2C(=C1)N=C(C(=N2)C3=CC=CO3)C4=CC=CO4
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| InChi Key |
GMUROSQCXMKHEN-UHFFFAOYSA-N
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| InChi Code |
InChI=1S/C16H10N2O2/c1-2-6-12-11(5-1)17-15(13-7-3-9-19-13)16(18-12)14-8-4-10-20-14/h1-10H
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| Chemical Name |
2,3-bis(furan-2-yl)quinoxaline
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| HS Tariff Code |
2934.99.9001
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| Storage |
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month |
| Shipping Condition |
Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)
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| Solubility (In Vitro) |
DMSO: 100 mg/mL (381.30 mM)
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| Solubility (In Vivo) |
Solubility in Formulation 1: ≥ 2.5 mg/mL (9.53 mM) (saturation unknown) in 10% DMSO + 40% PEG300 +5% Tween-80 + 45% Saline (add these co-solvents sequentially from left to right, and one by one), clear solution.
For example, if 1 mL of working solution is to be prepared, you can add 100 μL of 25.0 mg/mL clear DMSO stock solution to 400 μL PEG300 and mix evenly; then add 50 μL Tween-80 + to the above solution and mix evenly; then add 450 μL normal saline to adjust the volume to 1 mL. Preparation of saline: Dissolve 0.9 g of sodium chloride in 100 mL ddH₂ O to obtain a clear solution. (Please use freshly prepared in vivo formulations for optimal results.) |
| Preparing Stock Solutions | 1 mg | 5 mg | 10 mg | |
| 1 mM | 3.8130 mL | 19.0650 mL | 38.1301 mL | |
| 5 mM | 0.7626 mL | 3.8130 mL | 7.6260 mL | |
| 10 mM | 0.3813 mL | 1.9065 mL | 3.8130 mL |
*Note: Please select an appropriate solvent for the preparation of stock solution based on your experiment needs. For most products, DMSO can be used for preparing stock solutions (e.g. 5 mM, 10 mM, or 20 mM concentration); some products with high aqueous solubility may be dissolved in water directly. Solubility information is available at the above Solubility Data section. Once the stock solution is prepared, aliquot it to routine usage volumes and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles.
Calculation results
Working concentration： mg/mL；
Method for preparing DMSO stock solution： mg drug pre-dissolved in μL DMSO (stock solution concentration mg/mL). Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:：Take μL DMSO stock solution, next add μL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O，mix and clarify.
(1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
(2) Be sure to add the solvent(s) in order.
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