| Size | Price | |
|---|---|---|
| Other Sizes |
| Targets |
There is no specific molecular target reported for 2,3-Dimethylpyrazine. It is a volatile flavor compound used as an aroma ingredient and is also found as a natural product in various foods and antioxidant bacteria of the genus Streptomyces.
|
|---|---|
| ln Vitro |
There is no specific in vitro activity data available for this compound. It is detected as a volatile organic compound (VOC) in bacterial cultures, such as Rhodococcus erythropolis, which uses it as a growth medium component.
|
| ln Vivo |
There is no specific in vivo activity data available for this compound. As a volatile flavor compound that is generally regarded as safe for use in food, it has minimal biological activity beyond its organoleptic properties.
|
| Enzyme Assay |
There is no specific enzyme/receptor binding protocol for this compound. Analytical protocols for detecting 2,3-Dimethylpyrazine typically involve solid-phase microextraction (SPME) or headspace sampling followed by GC-MS analysis, using reference standards for identification and quantification.
|
| Cell Assay |
There is no specific cell-based protocol for this compound. A typical protocol for evaluating its effect on bacterial growth involves adding 2,3-Dimethylpyrazine (e.g., 0.1-10 mM) to culture medium for bacterial strains such as Rhodococcus erythropolis and measuring growth curves by OD600 after 24-72 hours of incubation.
|
| Animal Protocol |
There is no standard in vivo animal protocol for this compound. As a flavoring agent, its safety in animals has been assessed in general toxicity studies rather than specific pharmacological protocols.
|
| ADME/Pharmacokinetics |
General PK properties for 2,3-Dimethylpyrazine are not applicable for its use as a reagent. It is highly volatile and would be rapidly absorbed and excreted via the lungs. Formulation is typically as a neat liquid or in ethanol.
|
| Toxicity/Toxicokinetics |
General toxicity for 2,3-Dimethylpyrazine is considered low at the concentrations used in flavorings and research (mg/kg levels). Standard safety precautions for handling organic solvents and volatile liquids (adequate ventilation, avoidance of inhalation) should be observed.
|
| Additional Infomation |
2,3-Dimethylpyrazine is a type of pyrazine compound. It has been reported that 2,3-dimethylpyrazine is found in antioxidant bacteria of the genus Streptomyces, onions, and Corynebacterium glutamicum, and relevant data are available for reference.
2,3-Dimethylpyrazine is a pyrazine derivative widely used in biochemical experiments and drug synthesis research. It is also employed as a flavor and fragrance ingredient in the food industry. This product is for research use only. |
| Molecular Formula |
C6H8N2
|
|---|---|
| Molecular Weight |
108.14
|
| Exact Mass |
108.068
|
| CAS # |
5910-89-4
|
| PubChem CID |
22201
|
| Appearance |
Colorless to light yellow liquid
|
| Density |
1.0±0.1 g/cm3
|
| Boiling Point |
158.1±35.0 °C at 760 mmHg
|
| Melting Point |
11-13 °C
|
| Flash Point |
54.4±0.0 °C
|
| Vapour Pressure |
3.4±0.3 mmHg at 25°C
|
| Index of Refraction |
1.504
|
| LogP |
0.64
|
| Hydrogen Bond Donor Count |
0
|
| Hydrogen Bond Acceptor Count |
2
|
| Rotatable Bond Count |
0
|
| Heavy Atom Count |
8
|
| Complexity |
62.9
|
| Defined Atom Stereocenter Count |
0
|
| SMILES |
CC1=C(C)N=CC=N1
|
| InChi Key |
OXQOBQJCDNLAPO-UHFFFAOYSA-N
|
| InChi Code |
InChI=1S/C6H8N2/c1-5-6(2)8-4-3-7-5/h3-4H,1-2H3
|
| Chemical Name |
2,3-dimethylpyrazine
|
| HS Tariff Code |
2934.99.9001
|
| Storage |
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month |
| Shipping Condition |
Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)
|
| Solubility (In Vitro) |
DMSO: ≥ 100 mg/mL (~924.7 mM)
|
|---|---|
| Solubility (In Vivo) |
Solubility in Formulation 1: ≥ 2.5 mg/mL (23.12 mM) (saturation unknown) in 10% DMSO + 40% PEG300 + 5% Tween-80 + 45% Saline (add these co-solvents sequentially from left to right, and one by one), Clear solution.
For example, if 1 mL of working solution is to be prepared, you can add 100 μL of DMSO stock solution (25.0 mg/mL) to 400 μL of PEG300 and mix well; then add 50 μL of Tween-80 and mix well; finally add 450 μL of physiological saline and adjust the volume to 1 mL. Preparation of saline: Dissolve 0.9 g of sodium chloride in 100 mL ddH₂ O to obtain a clear solution. Solubility in Formulation 2: ≥ 2.5 mg/mL (23.12 mM) (saturation unknown) in 10% DMSO + 90% (20% SBE-β-CD in Saline) (add these co-solvents sequentially from left to right, and one by one), Clear solution. For example, if 1 mL of working solution is to be prepared, you can add 100 μL of DMSO stock solution (25.0 mg/mL) to 900 μL of 20% SBE-β-CD saline and mix well. Preparation of 20% SBE-β-CD in Saline (4°C，1 week): Dissolve 2 g SBE-β-CD in 10 mL saline to obtain a clear solution. Solubility in Formulation 3: ≥ 2.5 mg/mL (23.12 mM) (saturation unknown) in 10% DMSO + 90% Corn Oil (add these co-solvents sequentially from left to right, and one by one), Clear solution. For example, if 1 mL of working solution is to be prepared, you can add 100 μL of DMSO stock solution (25.0 mg/mL) to 900 μL of corn oil and mix well. (Please use freshly prepared in vivo formulations for optimal results.) |
| Preparing Stock Solutions | 1 mg | 5 mg | 10 mg | |
| 1 mM | 9.2473 mL | 46.2364 mL | 92.4727 mL | |
| 5 mM | 1.8495 mL | 9.2473 mL | 18.4945 mL | |
| 10 mM | 0.9247 mL | 4.6236 mL | 9.2473 mL |
*Note: Please select an appropriate solvent for the preparation of stock solution based on your experiment needs. For most products, DMSO can be used for preparing stock solutions (e.g. 5 mM, 10 mM, or 20 mM concentration); some products with high aqueous solubility may be dissolved in water directly. Solubility information is available at the above Solubility Data section. Once the stock solution is prepared, aliquot it to routine usage volumes and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles.
Calculation results
Working concentration： mg/mL；
Method for preparing DMSO stock solution： mg drug pre-dissolved in μL DMSO (stock solution concentration mg/mL). Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:：Take μL DMSO stock solution, next add μL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O，mix and clarify.
(1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
(2) Be sure to add the solvent(s) in order.
Products are for research use only; We do not sell to patients
Copyright 2020 InvivoChem LLC | All Rights Reserved
