| Size | Price | |
|---|---|---|
| Other Sizes |
| Targets |
2-(Pyrrolidin-1-yl)ethanol does not target a specific protein or enzyme for pharmacological intervention. Its utility is as a biochemical reagent and organic compound for life science research. The compound may serve as a building block for the synthesis of various pharmaceutical compounds.
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|---|---|
| ln Vitro |
The in vitro activity of 2-(Pyrrolidin-1-yl)ethanol is its function as a biochemical reagent and organic compound for life science related research. The compound can be used as a biological material or organic compound for research applications. Its structure, featuring a pyrrolidine ring and a hydroxyl group, makes it a versatile building block for organic synthesis.
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| ln Vivo |
No significant in vivo activity has been reported for 2-(Pyrrolidin-1-yl)ethanol as a therapeutic agent. The compound is primarily utilized as a chemical reagent and research intermediate rather than a pharmacologically active compound.
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| Enzyme Assay |
In vitro enzyme/receptor binding assays are not typically performed for 2-(Pyrrolidin-1-yl)ethanol, as it functions as a chemical reagent rather than a drug candidate. The compound is used in organic synthesis reactions where it serves as a building block.
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| Cell Assay |
For in vitro cellular experiments, 2-(Pyrrolidin-1-yl)ethanol is not typically used in cell-based assays. The compound is primarily used as a chemical intermediate in organic synthesis.
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| Animal Protocol |
In vivo animal experiments with 2-(Pyrrolidin-1-yl)ethanol are not commonly performed, as the compound is primarily used as a chemical reagent rather than a therapeutic candidate.
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| ADME/Pharmacokinetics |
Pharmacokinetic properties of 2-(Pyrrolidin-1-yl)ethanol have not been characterized, as it is a research-use chemical reagent rather than a drug candidate. The compound has a molecular weight of 115.18 g/mol and should be stored in pure form at -20°C for up to 3 years.
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| Toxicity/Toxicokinetics |
The compound is intended for research use only and not for human therapeutic or diagnostic applications. Standard laboratory safety precautions should be observed when handling this chemical reagent.
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| Additional Infomation |
Epolamine is a member of the pyrrolidine family. It is the conjugate base of 1-(2-hydroxyethyl)pyrrolidineonium.
2-(Pyrrolidin-1-yl)ethanol is a biochemical reagent that can be used as a biological material or organic compound for life science related research. The compound has no clinical or therapeutic applications. |
| Molecular Formula |
C6H13NO
|
|---|---|
| Molecular Weight |
115.18
|
| Exact Mass |
115.099
|
| CAS # |
2955-88-6
|
| Related CAS # |
30727-31-2 (hydrochloride)
|
| PubChem CID |
76288
|
| Appearance |
Colorless to light yellow liquid
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| Density |
1.0±0.1 g/cm3
|
| Boiling Point |
177.6±0.0 °C at 760 mmHg
|
| Flash Point |
56.1±0.0 °C
|
| Vapour Pressure |
0.3±0.7 mmHg at 25°C
|
| Index of Refraction |
1.484
|
| LogP |
0.49
|
| Hydrogen Bond Donor Count |
1
|
| Hydrogen Bond Acceptor Count |
2
|
| Rotatable Bond Count |
2
|
| Heavy Atom Count |
8
|
| Complexity |
59.5
|
| Defined Atom Stereocenter Count |
0
|
| SMILES |
O([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
|
| InChi Key |
XBRDBODLCHKXHI-UHFFFAOYSA-N
|
| InChi Code |
InChI=1S/C6H13NO/c8-6-5-7-3-1-2-4-7/h8H,1-6H2
|
| Chemical Name |
2-pyrrolidin-1-ylethanol
|
| HS Tariff Code |
2934.99.9001
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| Storage |
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month |
| Shipping Condition |
Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)
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| Solubility (In Vitro) |
DMSO: ~200 mg/mL (~1736.4 mM; with ultrasonication)
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|---|---|
| Solubility (In Vivo) |
Solubility in Formulation 1: ≥ 5 mg/mL (43.41 mM) (saturation unknown) in 10% DMSO + 40% PEG300 + 5% Tween-80 + 45% Saline (add these co-solvents sequentially from left to right, and one by one), Clear solution.
For example, if 1 mL of working solution is to be prepared, you can add 100 μL of DMSO stock solution (50.0 mg/mL) to 400 μL of PEG300 and mix well; then add 50 μL of Tween-80 and mix well; finally add 450 μL of physiological saline and adjust the volume to 1 mL. Preparation of saline: Dissolve 0.9 g of sodium chloride in 100 mL ddH₂ O to obtain a clear solution. Solubility in Formulation 2: ≥ 5 mg/mL (43.41 mM) (saturation unknown) in 10% DMSO + 90% (20% SBE-β-CD in Saline) (add these co-solvents sequentially from left to right, and one by one), Clear solution. For example, if 1 mL of working solution is to be prepared, you can add 100 μL of DMSO stock solution (50.0 mg/mL) to 900 μL of 20% SBE-β-CD saline and mix well. Preparation of 20% SBE-β-CD in Saline (4°C，1 week): Dissolve 2 g SBE-β-CD in 10 mL saline to obtain a clear solution. Solubility in Formulation 3: ≥ 5 mg/mL (43.41 mM) (saturation unknown) in 10% DMSO + 90% Corn Oil (add these co-solvents sequentially from left to right, and one by one), Clear solution. For example, if 1 mL of working solution is to be prepared, you can add 100 μL of DMSO stock solution (50.0 mg/mL) to 900 μL of corn oil and mix well. (Please use freshly prepared in vivo formulations for optimal results.) |
| Preparing Stock Solutions | 1 mg | 5 mg | 10 mg | |
| 1 mM | 8.6821 mL | 43.4103 mL | 86.8206 mL | |
| 5 mM | 1.7364 mL | 8.6821 mL | 17.3641 mL | |
| 10 mM | 0.8682 mL | 4.3410 mL | 8.6821 mL |
*Note: Please select an appropriate solvent for the preparation of stock solution based on your experiment needs. For most products, DMSO can be used for preparing stock solutions (e.g. 5 mM, 10 mM, or 20 mM concentration); some products with high aqueous solubility may be dissolved in water directly. Solubility information is available at the above Solubility Data section. Once the stock solution is prepared, aliquot it to routine usage volumes and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles.
Calculation results
Working concentration： mg/mL；
Method for preparing DMSO stock solution： mg drug pre-dissolved in μL DMSO (stock solution concentration mg/mL). Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:：Take μL DMSO stock solution, next add μL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O，mix and clarify.
(1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
(2) Be sure to add the solvent(s) in order.
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