| Size | Price | Stock | Qty |
|---|---|---|---|
| 250mg |
|
||
| 1g |
|
||
| Other Sizes |
| Targets |
1-Pyrenesulfonic acid sodium salt does not have a defined pharmacological target as it is a fluorescent probe and biochemical reagent. Its primary mechanism of action lies in its ability to act as a fluorescent probe due to the inherent fluorescent characteristics of the pyrene moiety. Upon UV excitation, the compound exhibits strong and distinctive fluorescence emission, which can be utilized to trace the distribution and interaction of the molecule within various systems.
|
|---|---|
| ln Vitro |
In vitro activity of 1-Pyrenesulfonic acid sodium salt is assessed in fluorescence-based assays. The compound has been used extensively in environmental and material science studies, particularly for tracing organic pollutants in water systems due to its high sensitivity and specificity for hydrophobic compounds. It has also been used in the study of micellar systems and the formation of polymer films, where its fluorescence properties enable detailed analysis of molecular interactions and dynamics. The compound also acts as an alignment agent in photoluminescent liquid crystal devices and as a surfactant and dopant in the synthesis of polypyrrole micro- and nanowires.
|
| ln Vivo |
No specific in vivo pharmacological activity data have been documented for 1-Pyrenesulfonic acid sodium salt as it is a fluorescent probe and research reagent. The compound is not administered to animals for pharmacological evaluation. Its applications are limited to in vitro biochemical, environmental, and material science research. It is not intended for diagnostic or therapeutic use.
|
| Enzyme Assay |
For non-cellular assays, 1-Pyrenesulfonic acid sodium salt is characterized by standard analytical techniques including fluorescence spectroscopy, NMR, and HPLC to confirm identity and purity. The compound can be evaluated as a fluorescent probe in various applications. Typical protocols involve dissolving the compound in aqueous or organic solvents and measuring fluorescence emission upon UV excitation. The compound has a molecular weight of 304.30 and molecular formula C16H9NaO3S. Purity is typically ≥95%.
|
| Cell Assay |
For in vitro cell-based studies, 1-Pyrenesulfonic acid sodium salt is used as a fluorescent probe for tracing and imaging applications. Cells are cultured under standard conditions and treated with the compound to assess cellular uptake, distribution, and interaction with cellular components. The compound's fluorescence properties enable detailed analysis of molecular interactions within complex systems. Appropriate controls including untreated cells should be included in the experimental design. The compound is for research use only.
|
| Animal Protocol |
For in vivo animal studies, 1-Pyrenesulfonic acid sodium salt is not typically administered as a test compound. The compound is used primarily in in vitro biochemical and material science research. If used in animal studies for tracing or imaging applications, it would be administered via appropriate routes with suitable formulations. Standard animal welfare guidelines should be followed for all in vivo studies. The compound is not intended for therapeutic use.
|
| ADME/Pharmacokinetics |
1-Pyrenesulfonic acid sodium salt has a molecular weight of 304.30 and molecular formula C16H9NaO3S. It is a water-soluble pyrene derivative. Storage: keep in a cool, dry place protected from light. The compound exhibits strong fluorescence upon UV excitation. Purity: typically ≥95%. Solubility: soluble in water and aqueous buffers due to the sulfonate group. The compound should be protected from light during storage and handling.
|
| Toxicity/Toxicokinetics |
1-Pyrenesulfonic acid sodium salt is for research use only and not intended for diagnostic or therapeutic use. Standard laboratory safety practices should be followed when handling this chemical. Appropriate personal protective equipment including gloves and safety glasses should be worn. Specific LD50 values and detailed toxicological profiles have not been extensively reported. The compound should be handled with care as with all laboratory chemicals.
|
| Additional Infomation |
1-Pyrenesulfonic acid sodium salt (CAS 59323-54-5) is also known as sodium 1-pyrenesulfonate. It is a fluorescent probe and functional building block in materials science. Applications include environmental tracing of organic pollutants, study of micellar systems, polymer film analysis, alignment agent in liquid crystal devices, and surfactant in nanowire synthesis. No clinical trials or therapeutic approvals exist.
|
| Molecular Formula |
C16H9NAO3S
|
|---|---|
| Molecular Weight |
304.30
|
| Exact Mass |
304.016
|
| CAS # |
59323-54-5
|
| PubChem CID |
23674489
|
| Appearance |
Off-white to yellow solid powder
|
| Melting Point |
233-236ºC(lit.)
|
| LogP |
4.568
|
| Hydrogen Bond Donor Count |
0
|
| Hydrogen Bond Acceptor Count |
3
|
| Rotatable Bond Count |
1
|
| Heavy Atom Count |
21
|
| Complexity |
486
|
| Defined Atom Stereocenter Count |
0
|
| SMILES |
C1=CC2=C3C(=C1)C=CC4=C(C=CC(=C43)C=C2)S(=O)(=O)[O-].[Na+]
|
| InChi Key |
HCOPYCNNZOWMTD-UHFFFAOYSA-M
|
| InChi Code |
InChI=1S/C16H10O3S.Na/c17-20(18,19)14-9-7-12-5-4-10-2-1-3-11-6-8-13(14)16(12)15(10)11;/h1-9H,(H,17,18,19);/q;+1/p-1
|
| Chemical Name |
sodium;pyrene-1-sulfonate
|
| HS Tariff Code |
2934.99.9001
|
| Storage |
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month Note: Please store this product in a sealed and protected environment, avoid exposure to moisture. |
| Shipping Condition |
Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)
|
| Solubility (In Vitro) |
May dissolve in DMSO (in most cases), if not, try other solvents such as H2O, Ethanol, or DMF with a minute amount of products to avoid loss of samples
|
|---|---|
| Solubility (In Vivo) |
Note: Listed below are some common formulations that may be used to formulate products with low water solubility (e.g. < 1 mg/mL), you may test these formulations using a minute amount of products to avoid loss of samples.
Injection Formulations
Injection Formulation 1: DMSO : Tween 80： Saline = 10 : 5 : 85 (i.e. 100 μL DMSO stock solution → 50 μL Tween 80 → 850 μL Saline)(e.g. IP/IV/IM/SC) *Preparation of saline: Dissolve 0.9 g of sodium chloride in 100 mL ddH ₂ O to obtain a clear solution. Injection Formulation 2: DMSO : PEG300 ：Tween 80 : Saline = 10 : 40 : 5 : 45 (i.e. 100 μL DMSO → 400 μLPEG300 → 50 μL Tween 80 → 450 μL Saline) Injection Formulation 3: DMSO : Corn oil = 10 : 90 (i.e. 100 μL DMSO → 900 μL Corn oil) Example: Take the Injection Formulation 3 (DMSO : Corn oil = 10 : 90) as an example, if 1 mL of 2.5 mg/mL working solution is to be prepared, you can take 100 μL 25 mg/mL DMSO stock solution and add to 900 μL corn oil, mix well to obtain a clear or suspension solution (2.5 mg/mL, ready for use in animals). View More
Injection Formulation 4: DMSO : 20% SBE-β-CD in saline = 10 : 90 [i.e. 100 μL DMSO → 900 μL (20% SBE-β-CD in saline)] Oral Formulations
Oral Formulation 1: Suspend in 0.5% CMC Na (carboxymethylcellulose sodium) Oral Formulation 2: Suspend in 0.5% Carboxymethyl cellulose Example: Take the Oral Formulation 1 (Suspend in 0.5% CMC Na) as an example, if 100 mL of 2.5 mg/mL working solution is to be prepared, you can first prepare 0.5% CMC Na solution by measuring 0.5 g CMC Na and dissolve it in 100 mL ddH2O to obtain a clear solution; then add 250 mg of the product to 100 mL 0.5% CMC Na solution, to make the suspension solution (2.5 mg/mL, ready for use in animals). View More
Oral Formulation 3: Dissolved in PEG400 (Please use freshly prepared in vivo formulations for optimal results.) |
| Preparing Stock Solutions | 1 mg | 5 mg | 10 mg | |
| 1 mM | 3.2862 mL | 16.4312 mL | 32.8623 mL | |
| 5 mM | 0.6572 mL | 3.2862 mL | 6.5725 mL | |
| 10 mM | 0.3286 mL | 1.6431 mL | 3.2862 mL |
*Note: Please select an appropriate solvent for the preparation of stock solution based on your experiment needs. For most products, DMSO can be used for preparing stock solutions (e.g. 5 mM, 10 mM, or 20 mM concentration); some products with high aqueous solubility may be dissolved in water directly. Solubility information is available at the above Solubility Data section. Once the stock solution is prepared, aliquot it to routine usage volumes and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles.
Calculation results
Working concentration： mg/mL；
Method for preparing DMSO stock solution： mg drug pre-dissolved in μL DMSO (stock solution concentration mg/mL). Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:：Take μL DMSO stock solution, next add μL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O，mix and clarify.
(1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
(2) Be sure to add the solvent(s) in order.
Products are for research use only; We do not sell to patients
Copyright 2020 InvivoChem LLC | All Rights Reserved
