| Size | Price | |
|---|---|---|
| Other Sizes |
| Targets |
D-Galactal does not have a defined pharmacological target as it is a carbohydrate building block and biochemical reagent. The compound is a sugar derivative that has attracted attention in glycobiology research due to its role as a precursor in the synthesis of various carbohydrate structures. It is a key intermediate in the biosynthesis of complex carbohydrates such as glycoproteins, glycolipids, and polysaccharides.
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|---|---|
| ln Vitro |
In vitro activity of D-Galactal is assessed in carbohydrate synthesis studies. The compound is used as a substrate for enzyme assays and as a building block for oligosaccharide synthesis. Researchers utilize D-Galactal as a substrate for enzyme assays and as a key intermediate in the synthesis of complex carbohydrates.
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| ln Vivo |
No specific in vivo pharmacological activity data have been documented for D-Galactal as a therapeutic agent. The compound is used as a carbohydrate building block and biochemical reagent. It is not administered to animals for pharmacological evaluation. Its applications are limited to glycobiology and carbohydrate synthesis research.
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| Enzyme Assay |
For non-cellular assays, D-Galactal is characterized by standard analytical techniques including HPLC, NMR, and mass spectrometry to confirm identity and purity. The compound can be evaluated as a substrate in carbohydrate synthesis and enzyme assays. Purity: >95.0% by HPLC. Molecular weight: 146.14.
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| Cell Assay |
For in vitro cell-based studies, D-Galactal is not typically used as a direct test compound. The compound is used as a building block for synthesizing complex carbohydrates and as a substrate in enzyme assays. If handled in a biological laboratory context, standard safety precautions should be taken.
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| Animal Protocol |
For in vivo animal studies, D-Galactal can be formulated using standard injection vehicles. The compound is a solid at room temperature. Dosing solutions should be freshly prepared and administered according to specific protocols with appropriate control groups.
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| ADME/Pharmacokinetics |
D-Galactal has a molecular weight of 146.14 and molecular formula C6H10O4. Purity: >95.0% by HPLC. Storage: keep in a cool, dry place protected from light and moisture. The compound is a white to off-white solid. Solubility: soluble in common organic solvents.
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| Toxicity/Toxicokinetics |
D-Galactal is for research use only and not for human consumption. Standard laboratory safety practices should be followed when handling this chemical. Appropriate personal protective equipment including gloves and safety glasses should be worn. Specific LD50 values and detailed toxicological profiles have not been extensively reported.
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| Additional Infomation |
D-Galacturonic acid is a glycoside derived from D-galactopyranose. It is a glycoside and also a dehydrated hexose.
D-Galactal (CAS 21193-75-9) is also known as 1,5-anhydro-2-deoxy-D-lyxo-hex-1-enitol and D-galactal. It is an important building block for oligosaccharide synthesis and a key intermediate in complex carbohydrate biosynthesis. Applications include glycobiology research and carbohydrate chemistry. No clinical trials or therapeutic approvals exist. |
| Molecular Formula |
C6H10O4
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|---|---|
| Molecular Weight |
146.14
|
| Exact Mass |
146.057
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| CAS # |
21193-75-9
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| PubChem CID |
2734735
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| Appearance |
White to off-white solid powder
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| Density |
1.4±0.1 g/cm3
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| Boiling Point |
325.5±42.0 °C at 760 mmHg
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| Melting Point |
99-102 °C
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| Flash Point |
150.7±27.9 °C
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| Vapour Pressure |
0.0±1.6 mmHg at 25°C
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| Index of Refraction |
1.565
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| LogP |
-1.8
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| Hydrogen Bond Donor Count |
3
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| Hydrogen Bond Acceptor Count |
4
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| Rotatable Bond Count |
1
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| Heavy Atom Count |
10
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| Complexity |
134
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| Defined Atom Stereocenter Count |
3
|
| SMILES |
C1=CO[C@@H]([C@@H]([C@@H]1O)O)CO
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| InChi Key |
YVECGMZCTULTIS-HSUXUTPPSA-N
|
| InChi Code |
InChI=1S/C6H10O4/c7-3-5-6(9)4(8)1-2-10-5/h1-2,4-9H,3H2/t4-,5-,6-/m1/s1
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| Chemical Name |
(2R,3R,4R)-2-(hydroxymethyl)-3,4-dihydro-2H-pyran-3,4-diol
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| HS Tariff Code |
2934.99.9001
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| Storage |
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month |
| Shipping Condition |
Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)
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| Solubility (In Vitro) |
DMSO: ≥ 200 mg/mL (~1368.6 mM)
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|---|---|
| Solubility (In Vivo) |
Solubility in Formulation 1: ≥ 5 mg/mL (34.21 mM) (saturation unknown) in 10% DMSO + 40% PEG300 + 5% Tween-80 + 45% Saline (add these co-solvents sequentially from left to right, and one by one), Clear solution.
For example, if 1 mL of working solution is to be prepared, you can add 100 μL of DMSO stock solution (50.0 mg/mL) to 400 μL of PEG300 and mix well; then add 50 μL of Tween-80 and mix well; finally add 450 μL of physiological saline and adjust the volume to 1 mL. Preparation of saline: Dissolve 0.9 g of sodium chloride in 100 mL ddH₂ O to obtain a clear solution. Solubility in Formulation 2: ≥ 5 mg/mL (34.21 mM) (saturation unknown) in 10% DMSO + 90% (20% SBE-β-CD in Saline) (add these co-solvents sequentially from left to right, and one by one), Clear solution. For example, if 1 mL of working solution is to be prepared, you can add 100 μL of DMSO stock solution (50.0 mg/mL) to 900 μL of 20% SBE-β-CD saline and mix well. Preparation of 20% SBE-β-CD in Saline (4°C，1 week): Dissolve 2 g SBE-β-CD in 10 mL saline to obtain a clear solution. (Please use freshly prepared in vivo formulations for optimal results.) |
| Preparing Stock Solutions | 1 mg | 5 mg | 10 mg | |
| 1 mM | 6.8428 mL | 34.2138 mL | 68.4275 mL | |
| 5 mM | 1.3686 mL | 6.8428 mL | 13.6855 mL | |
| 10 mM | 0.6843 mL | 3.4214 mL | 6.8428 mL |
*Note: Please select an appropriate solvent for the preparation of stock solution based on your experiment needs. For most products, DMSO can be used for preparing stock solutions (e.g. 5 mM, 10 mM, or 20 mM concentration); some products with high aqueous solubility may be dissolved in water directly. Solubility information is available at the above Solubility Data section. Once the stock solution is prepared, aliquot it to routine usage volumes and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles.
Calculation results
Working concentration： mg/mL；
Method for preparing DMSO stock solution： mg drug pre-dissolved in μL DMSO (stock solution concentration mg/mL). Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:：Take μL DMSO stock solution, next add μL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O，mix and clarify.
(1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
(2) Be sure to add the solvent(s) in order.
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