| Size | Price | Stock | Qty |
|---|---|---|---|
| 100g |
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| 500g | |||
| Other Sizes |
Purity: =100%
| Targets |
DCTA monohydrate does not have a defined pharmacological target as it is a chelating agent and biochemical reagent. The compound works as a chelating agent and complexing reagent for metal ions. It can form stable complexes with many metal ions such as calcium ions, magnesium ions, and zinc ions. After modification with ethylene glycol, DCTA shows selectivity for calcium ions in the presence of magnesium ions.
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|---|---|
| ln Vitro |
No specific in vitro pharmacological activity data are available for DCTA monohydrate as it is a chelating agent. In research settings, the compound is used as a chelating agent and coordination reagent for metal ions. Its activity is assessed in terms of metal ion binding affinity and chelation efficiency rather than direct biological activity. It is used as an analytical reagent and a complexating agent.
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| ln Vivo |
No specific in vivo pharmacological activity data have been documented for DCTA monohydrate as a therapeutic agent. The compound is used as a chelating agent and biochemical reagent. It is not administered to animals for pharmacological evaluation. Its applications are limited to in vitro biochemical research and analytical chemistry.
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| Enzyme Assay |
For non-cellular assays, DCTA monohydrate is characterized by standard analytical techniques including HPLC, NMR, and mass spectrometry to confirm identity and purity. The compound can be evaluated for its metal chelation capacity using various analytical methods. Typical protocols involve titrating the compound with metal ion solutions and measuring complex formation. Purity: ≥99%. Storage: room temperature in a cool and dry place.
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| Cell Assay |
For in vitro cell-based studies, DCTA monohydrate is not typically used as a direct test compound. It is used as a chelating agent in cell culture media and buffers to control metal ion concentrations. If handled in a biological laboratory context, standard safety precautions should be taken. The compound is a solid at room temperature.
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| Animal Protocol |
For in vivo animal studies, DCTA monohydrate is not typically administered as a test compound. It is used as a chelating agent and biochemical reagent. If used in animal studies for specific research purposes, it would be administered via appropriate routes with suitable formulations. Standard animal welfare guidelines should be followed.
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| ADME/Pharmacokinetics |
DCTA monohydrate has a molecular weight of approximately 364.35 g/mol and molecular formula C₁₄H₂₂N₂O₈·H₂O. Purity: ≥99%. Storage: keep in a cool, dry place protected from light and moisture. The compound is a solid at room temperature. Solubility: soluble in aqueous bases. The compound is stable under recommended storage conditions.
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| Toxicity/Toxicokinetics |
DCTA monohydrate is for research use only and not for human consumption. Standard laboratory safety practices should be followed when handling this chemical. Appropriate personal protective equipment including gloves and safety glasses should be worn. Specific LD₅₀ values and detailed toxicological profiles have not been extensively reported.
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| References |
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| Additional Infomation |
DCTA monohydrate (CAS 125572-95-4) is also known as trans-1,2-diaminocyclohexane-N,N,N',N'-tetraacetic acid monohydrate. It is a multidentate ligand used as a chelating agent in the preparation of metal-chelate complexes. It is an analytical reagent and a complexating agent for sodium and is used to prepare lanthanide shift reagents. No clinical trials or therapeutic approvals exist.
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| Molecular Formula |
C14H24N2O9
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|---|---|
| Molecular Weight |
364.35
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| Exact Mass |
364.148
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| CAS # |
125572-95-4
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| PubChem CID |
2723844
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| Appearance |
White to off-white solid powder
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| Boiling Point |
734.7ºC at 760 mmHg
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| Melting Point |
213-216 °C(lit.)
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| Flash Point |
398.2ºC
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| Vapour Pressure |
9.77E-20mmHg at 25°C
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| Hydrogen Bond Donor Count |
5
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| Hydrogen Bond Acceptor Count |
11
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| Rotatable Bond Count |
10
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| Heavy Atom Count |
25
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| Complexity |
419
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| Defined Atom Stereocenter Count |
2
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| SMILES |
C1CC[C@H]([C@@H](C1)N(CC(=O)O)CC(=O)O)N(CC(=O)O)CC(=O)O.O
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| InChi Key |
VASZYFIKPKYGNC-DHTOPLTISA-N
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| InChi Code |
InChI=1S/C14H22N2O8.H2O/c17-11(18)5-15(6-12(19)20)9-3-1-2-4-10(9)16(7-13(21)22)8-14(23)24;/h9-10H,1-8H2,(H,17,18)(H,19,20)(H,21,22)(H,23,24);1H2/t9-,10-;/m1./s1
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| Chemical Name |
2-[[(1R,2R)-2-[bis(carboxymethyl)amino]cyclohexyl]-(carboxymethyl)amino]acetic acid;hydrate
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| HS Tariff Code |
2934.99.9001
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| Storage |
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month Note: (1). This product requires protection from light (avoid light exposure) during transportation and storage. (2). Please store this product in a sealed and protected environment (e.g. under nitrogen), avoid exposure to moisture. |
| Shipping Condition |
Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)
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| Solubility (In Vitro) |
DMSO: 25 mg/mL (68.62 mM)
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|---|---|
| Solubility (In Vivo) |
Solubility in Formulation 1: ≥ 2.5 mg/mL (6.86 mM) (saturation unknown) in 10% DMSO + 90% Corn Oil (add these co-solvents sequentially from left to right, and one by one), clear solution.
For example, if 1 mL of working solution is to be prepared, you can add 100 μL of 25.0 mg/mL clear DMSO stock solution to 900 μL of corn oil and mix evenly. (Please use freshly prepared in vivo formulations for optimal results.) |
| Preparing Stock Solutions | 1 mg | 5 mg | 10 mg | |
| 1 mM | 2.7446 mL | 13.7231 mL | 27.4461 mL | |
| 5 mM | 0.5489 mL | 2.7446 mL | 5.4892 mL | |
| 10 mM | 0.2745 mL | 1.3723 mL | 2.7446 mL |
*Note: Please select an appropriate solvent for the preparation of stock solution based on your experiment needs. For most products, DMSO can be used for preparing stock solutions (e.g. 5 mM, 10 mM, or 20 mM concentration); some products with high aqueous solubility may be dissolved in water directly. Solubility information is available at the above Solubility Data section. Once the stock solution is prepared, aliquot it to routine usage volumes and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles.
Calculation results
Working concentration： mg/mL；
Method for preparing DMSO stock solution： mg drug pre-dissolved in μL DMSO (stock solution concentration mg/mL). Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:：Take μL DMSO stock solution, next add μL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O，mix and clarify.
(1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
(2) Be sure to add the solvent(s) in order.
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