| Size | Price | |
|---|---|---|
| Other Sizes |
| Targets |
(2-Dodecen-1-yl)succinic anhydride is a chemical intermediate and polymerization reagent rather than a direct pharmacological agent. As a reagent, it does not have specific biological receptors as its primary targets. Its mechanism of action in polymerization involves the anhydride functionality reacting with nucleophiles (e.g., alcohols, amines) to form esters or amides, serving as a cross-linking or modifying agent for polymers. Its primary applications are in the production of plastics, resins, coatings, inks, and textile manufacturing.
|
|---|---|
| ln Vitro |
Succinic anhydride, also known as 2-dodecenyl)-8CI, is a biochemical reagent that can be utilized in research pertaining to life sciences as an organic compound or biological material.
In vitro, (2-dodecen-1-yl)succinic anhydride is used as an organic/chemical reagent widely used in polymerization reactions. It may be utilized to make products such as plastics and resins. Cellular assays are not typically performed with this compound as a direct cell-modulating agent, as its primary applications are in polymer chemistry and materials science. The compound's anhydride functionality makes it valuable for modifying polymers and surfaces. |
| ln Vivo |
In vivo data for (2-dodecen-1-yl)succinic anhydride is limited, as it is primarily an industrial chemical and polymerization reagent. The compound is classified for research use only and is not intended for human or veterinary therapeutic applications. Its primary applications are in the production of plastics, resins, coatings, and inks. The compound's anhydride functionality would likely be hydrolyzed in biological systems. Specific in vivo data for the parent compound is not available in the public literature.
|
| Enzyme Assay |
In vitro assays for (2-dodecen-1-yl)succinic anhydride typically evaluate its use as a polymerization reagent or surface modifier. A standard protocol involves reacting the compound with nucleophiles (e.g., alcohols, amines) in organic solvents to form esters or amides. Reaction progress is monitored by TLC, IR spectroscopy, or NMR. The compound's reactivity and efficiency as a modifying agent are evaluated by the degree of functionalization of the target polymer or surface. The compound's purity and identity are confirmed by standard analytical techniques.
|
| Cell Assay |
Cellular assays for (2-dodecen-1-yl)succinic anhydride are not standard, as the compound is primarily used in polymer chemistry rather than as a cell-modulating agent. The compound's anhydride functionality suggests potential for reactivity with cellular nucleophiles and cytotoxicity at high concentrations. Any cellular studies would focus on evaluating the compound's cytotoxicity. A typical protocol would involve culturing appropriate cell lines in growth medium at 37°C with 5% CO₂. Cells would be treated with varying concentrations of the compound. Cell viability would be assessed using MTT or similar assays.
|
| Animal Protocol |
In vivo animal studies for (2-dodecen-1-yl)succinic anhydride are not standard, as it is primarily an industrial chemical and polymerization reagent. The compound is classified for research use only and is not intended for human or veterinary applications. Any animal studies would be limited to toxicological evaluations of the compound as an industrial chemical. The compound's anhydride functionality suggests potential for irritation and toxicity. Specific in vivo protocols are not available in the public literature.
|
| ADME/Pharmacokinetics |
Pharmacokinetic data for (2-dodecen-1-yl)succinic anhydride is limited, as it is primarily an industrial chemical. The compound has a molecular weight of 266.38 g/mol and a molecular formula of C₁₆H₂₆O₃. It is a solid at room temperature. As an anhydride, it is reactive and would hydrolyze in aqueous environments to the corresponding diacid. Specific ADME data is not available. The compound is stored in a dry, cool place.
|
| Toxicity/Toxicokinetics |
(2-Dodecen-1-yl)succinic anhydride is classified for research use only and is not intended for human or veterinary applications. Standard safety precautions include handling with appropriate personal protective equipment (gloves, lab coat, safety goggles) in a well-ventilated area. The compound should be stored in a dry, cool place away from incompatible materials. Acute toxicity data is not readily available in the public literature. As with all research chemicals, appropriate laboratory safety practices should be followed. No specific LD₅₀ values are available in the public domain.
|
| Additional Infomation |
2-Dodecen-1-ylsuccinic anhydride is a pale yellow, transparent, viscous oil. (NTP, 1992)
See also: 2,5-furandione, dihydro-3-(tetrapropenyl)- (note moved to). (2-Dodecen-1-yl)succinic anhydride (Dodecenylsuccinic anhydride, CAS 19780-11-1) is a biochemical reagent with the molecular formula C₁₆H₂₆O₃ and a molecular weight of 266.38 g/mol. It is used in polymerization reactions for the production of plastics, resins, coatings, inks, and textile manufacturing. The compound is classified as a research-use-only reagent and is available from multiple commercial suppliers. |
| Molecular Formula |
C16H26O3
|
|---|---|
| Molecular Weight |
266.38
|
| Exact Mass |
266.188
|
| CAS # |
19780-11-1
|
| PubChem CID |
5362708
|
| Appearance |
White to off-white solid powder
|
| Density |
1.0±0.1 g/cm3
|
| Boiling Point |
348.4±0.0 °C at 760 mmHg
|
| Melting Point |
41-43ºC(lit.)
|
| Flash Point |
177.8±0.0 °C
|
| Vapour Pressure |
0.0±0.7 mmHg at 25°C
|
| Index of Refraction |
1.477
|
| LogP |
4.69
|
| Hydrogen Bond Donor Count |
0
|
| Hydrogen Bond Acceptor Count |
3
|
| Rotatable Bond Count |
10
|
| Heavy Atom Count |
19
|
| Complexity |
307
|
| Defined Atom Stereocenter Count |
0
|
| SMILES |
O=C(O1)C(C/C=C/CCCCCCCCC)CC1=O
|
| InChi Key |
UYCICMIUKYEYEU-ZHACJKMWSA-N
|
| InChi Code |
InChI=1S/C16H26O3/c1-2-3-4-5-6-7-8-9-10-11-12-14-13-15(17)19-16(14)18/h10-11,14H,2-9,12-13H2,1H3/b11-10+
|
| Chemical Name |
3-[(E)-dodec-2-enyl]oxolane-2,5-dione
|
| HS Tariff Code |
2934.99.9001
|
| Storage |
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month Note: This product requires protection from light (avoid light exposure) during transportation and storage. |
| Shipping Condition |
Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)
|
| Solubility (In Vitro) |
DMSO: 250 mg/mL (938.51 mM)
|
|---|---|
| Solubility (In Vivo) |
Solubility in Formulation 1: ≥ 2.08 mg/mL (7.81 mM) (saturation unknown) in 10% DMSO + 90% (20% SBE-β-CD in Saline) (add these co-solvents sequentially from left to right, and one by one), clear solution.
For example, if 1 mL of working solution is to be prepared, you can add 100 μL of 20.8 mg/mL clear DMSO stock solution to 900 μL of 20% SBE-β-CD physiological saline solution and mix evenly. Preparation of 20% SBE-β-CD in Saline (4°C，1 week): Dissolve 2 g SBE-β-CD in 10 mL saline to obtain a clear solution. Solubility in Formulation 2: ≥ 2.08 mg/mL (7.81 mM) (saturation unknown) in 10% DMSO + 90% Corn Oil (add these co-solvents sequentially from left to right, and one by one), clear solution. For example, if 1 mL of working solution is to be prepared, you can add 100 μL of 20.8 mg/mL clear DMSO stock solution to 900 μL of corn oil and mix evenly. (Please use freshly prepared in vivo formulations for optimal results.) |
| Preparing Stock Solutions | 1 mg | 5 mg | 10 mg | |
| 1 mM | 3.7540 mL | 18.7702 mL | 37.5404 mL | |
| 5 mM | 0.7508 mL | 3.7540 mL | 7.5081 mL | |
| 10 mM | 0.3754 mL | 1.8770 mL | 3.7540 mL |
*Note: Please select an appropriate solvent for the preparation of stock solution based on your experiment needs. For most products, DMSO can be used for preparing stock solutions (e.g. 5 mM, 10 mM, or 20 mM concentration); some products with high aqueous solubility may be dissolved in water directly. Solubility information is available at the above Solubility Data section. Once the stock solution is prepared, aliquot it to routine usage volumes and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles.
Calculation results
Working concentration： mg/mL；
Method for preparing DMSO stock solution： mg drug pre-dissolved in μL DMSO (stock solution concentration mg/mL). Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:：Take μL DMSO stock solution, next add μL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O，mix and clarify.
(1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
(2) Be sure to add the solvent(s) in order.
Products are for research use only; We do not sell to patients
Copyright 2020 InvivoChem LLC | All Rights Reserved
