| Size | Price | Stock | Qty |
|---|---|---|---|
| 500mg |
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| Other Sizes |
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| References |
[1]. Melissa D Mertzman, et al. Effect of surfactant concentration and buffer selection on chromatographic figures of merit in chiral microemulsion electrokinetic chromatography. Electrophoresis. 2004 Oct;25(18-19):3247-56.
[2]. Rabindra N Roy, et al. Buffer Standards for the Physiological pH of the Zwitterionic Compound, ACES from 5 to 55°C. J Solution Chem. 2009 Apr 1;38(4):471-483. |
|---|---|
| Additional Infomation |
N-(2-acetamido)-2-aminoethanesulfonic acid is a Good's buffer substance, pKa = 6.9 at 20 ℃. It is an ACES and an amino sulfonic acid. It is a tautomer of a 2-[(2-amino-2-oxoethyl)ammonio]ethanesulfonate.
|
| Molecular Formula |
C4H10N2O4S
|
|---|---|
| Molecular Weight |
182.20
|
| Exact Mass |
182.036
|
| CAS # |
7365-82-4
|
| PubChem CID |
81832
|
| Appearance |
White to off-white solid powder
|
| Density |
1.5±0.1 g/cm3
|
| Melting Point |
>220 °C (dec.)(lit.)
|
| Index of Refraction |
1.537
|
| LogP |
-3.24
|
| Hydrogen Bond Donor Count |
3
|
| Hydrogen Bond Acceptor Count |
5
|
| Rotatable Bond Count |
5
|
| Heavy Atom Count |
11
|
| Complexity |
217
|
| Defined Atom Stereocenter Count |
0
|
| SMILES |
S(C([H])([H])C([H])([H])N([H])C([H])([H])C(N([H])[H])=O)(=O)(=O)O[H]
|
| InChi Key |
DBXNUXBLKRLWFA-UHFFFAOYSA-N
|
| InChi Code |
InChI=1S/C4H10N2O4S/c5-4(7)3-6-1-2-11(8,9)10/h6H,1-3H2,(H2,5,7)(H,8,9,10)
|
| Chemical Name |
2-[(2-amino-2-oxoethyl)amino]ethanesulfonic acid
|
| HS Tariff Code |
2934.99.9001
|
| Storage |
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month |
| Shipping Condition |
Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)
|
| Solubility (In Vitro) |
H2O: 41.67 mg/mL (228.70 mM)
|
|---|---|
| Solubility (In Vivo) |
Solubility in Formulation 1: 16.67 mg/mL (91.49 mM) in PBS (add these co-solvents sequentially from left to right, and one by one), clear solution; with sonication.
(Please use freshly prepared in vivo formulations for optimal results.) |
| Preparing Stock Solutions | 1 mg | 5 mg | 10 mg | |
| 1 mM | 5.4885 mL | 27.4424 mL | 54.8847 mL | |
| 5 mM | 1.0977 mL | 5.4885 mL | 10.9769 mL | |
| 10 mM | 0.5488 mL | 2.7442 mL | 5.4885 mL |
*Note: Please select an appropriate solvent for the preparation of stock solution based on your experiment needs. For most products, DMSO can be used for preparing stock solutions (e.g. 5 mM, 10 mM, or 20 mM concentration); some products with high aqueous solubility may be dissolved in water directly. Solubility information is available at the above Solubility Data section. Once the stock solution is prepared, aliquot it to routine usage volumes and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles.
Calculation results
Working concentration： mg/mL；
Method for preparing DMSO stock solution： mg drug pre-dissolved in μL DMSO (stock solution concentration mg/mL). Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:：Take μL DMSO stock solution, next add μL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O，mix and clarify.
(1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
(2) Be sure to add the solvent(s) in order.
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