| Size | Price | Stock | Qty |
|---|---|---|---|
| 5mg |
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| 10mg |
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| Other Sizes |
| Targets |
The primary targets of D-Panose are not well-defined, as it functions primarily as a nutritional carbohydrate rather than a pharmacologically active compound. As a trisaccharide, it may interact with carbohydrate-binding proteins, transporters, and digestive enzymes such as alpha-glucosidases. Its role as a food ingredient suggests that it is metabolized to provide energy, and it may have prebiotic effects by serving as a substrate for beneficial gut bacteria.
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|---|---|
| ln Vitro |
In vitro activity studies for D-Panose are limited, as the compound is primarily used as a food ingredient and biochemical reagent. It may be used in studies of carbohydrate metabolism and enzyme specificity. As a trisaccharide, it can serve as a substrate for glycosidases in enzymatic assays. Its surface-assisted laser desorption-ionization mass spectrometry (SALDI-MS) properties have been investigated using magnesium oxide nanoparticles as a matrix.
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| ln Vivo |
In vivo activity data for D-Panose are primarily related to its nutritional properties as a food ingredient. As a carbohydrate based on isomaltooligosaccharides, it is metabolized to provide energy. It may have prebiotic effects by promoting the growth of beneficial gut bacteria. However, specific pharmacological activities in vivo have not been extensively characterized.
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| Enzyme Assay |
Non-cellular assays for D-Panose typically involve analytical characterization methods such as surface-assisted laser desorption-ionization mass spectrometry (SALDI-MS) using magnesium oxide nanoparticles as a matrix. These techniques are used to analyze oligosaccharide structure and composition. The compound's physical properties including optical activity ([α]/D 153±8°) have been characterized. Solubility testing in water (100-125 mg/mL) is performed to assess its physical properties.
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| Cell Assay |
Cellular assays for D-Panose are limited, as the compound is not typically used in cell-based pharmacological studies. It may be used in cell culture media as a carbohydrate source or in studies of carbohydrate metabolism and transport. Its effects on cell viability and metabolism are generally not studied, as it functions as a nutritional component rather than a bioactive compound with specific cellular targets.
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| Animal Protocol |
In vivo animal experiments for D-Panose are not typically conducted, as the compound is a food ingredient rather than a therapeutic agent. It may be used in nutritional studies to assess the metabolic effects of isomaltooligosaccharide-based carbohydrates. In such studies, animals are fed diets containing D-Panose, and metabolic parameters such as blood glucose, insulin levels, and gut microbiota composition are measured.
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| ADME/Pharmacokinetics |
Pharmacokinetic properties of D-Panose are not well-characterized, as it is a food ingredient rather than a pharmaceutical compound. As a trisaccharide, it is likely hydrolyzed by intestinal glycosidases into monosaccharides (glucose) before absorption. It is soluble in water (100-125 mg/mL) and is stable as a solid powder. The compound should be stored at 4°C protected from light, and in solvent at -80°C for up to 6 months.
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| Toxicity/Toxicokinetics |
Toxicological data for D-Panose are limited, as it is a food-grade carbohydrate derived from isomaltooligosaccharides. It is generally recognized as safe (GRAS) as a food ingredient. No significant toxicity has been reported for this compound. Standard laboratory safety precautions should be followed when handling the compound, though it is not considered hazardous.
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| References |
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| Additional Infomation |
Panose is a trisaccharide composed of D-glucanose units that plays a role in plant metabolism. Panose has been reported in Drosophila melanogaster, and relevant data are available for reference.
Other information for D-Panose includes its use as a food ingredient and its characterization as a PAN-type oligosaccharide. It has been identified as a plant metabolite and has been reported in Drosophila melanogaster with data available. The compound is used in biochemical research, particularly in studies of oligosaccharide structure and function. Its physical properties include a density of 1.8±0.1 g/cm3 and a boiling point of 960.0±65.0 °C at 760 mmHg. |
| Molecular Formula |
C18H32O16
|
|---|---|
| Molecular Weight |
504.44
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| Exact Mass |
504.169
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| CAS # |
33401-87-5
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| PubChem CID |
94448
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| Appearance |
White to off-white solid powder
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| Density |
1.75 g/cm3
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| Boiling Point |
960ºC at 760 mmHg
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| Melting Point |
223ºC
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| Flash Point |
330.1ºC
|
| Index of Refraction |
155 ° (C=2, H2O)
|
| LogP |
-7.2
|
| Hydrogen Bond Donor Count |
11
|
| Hydrogen Bond Acceptor Count |
16
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| Rotatable Bond Count |
11
|
| Heavy Atom Count |
34
|
| Complexity |
625
|
| Defined Atom Stereocenter Count |
14
|
| SMILES |
C([C@@H]1[C@H]([C@@H]([C@H]([C@H](O1)OC[C@@H]2[C@H]([C@@H]([C@H]([C@H](O2)O[C@H]([C@@H](CO)O)[C@@H]([C@H](C=O)O)O)O)O)O)O)O)O)O
|
| InChi Key |
ZCLAHGAZPPEVDX-MQHGYYCBSA-N
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| InChi Code |
InChI=1S/C18H32O16/c19-1-5(22)9(24)16(6(23)2-20)34-18-15(30)13(28)11(26)8(33-18)4-31-17-14(29)12(27)10(25)7(3-21)32-17/h1,5-18,20-30H,2-4H2/t5-,6+,7+,8+,9+,10+,11+,12-,13-,14+,15+,16+,17-,18+/m0/s1
|
| Chemical Name |
(2R,3R,4R,5R)-2,3,5,6-tetrahydroxy-4-[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-[[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxymethyl]oxan-2-yl]oxyhexanal
|
| HS Tariff Code |
2934.99.9001
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| Storage |
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month Note: This product requires protection from light (avoid light exposure) during transportation and storage. |
| Shipping Condition |
Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)
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| Solubility (In Vitro) |
H2O: 125 mg/mL (247.80 mM)
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|---|---|
| Solubility (In Vivo) |
Solubility in Formulation 1: 100 mg/mL (198.24 mM) in PBS (add these co-solvents sequentially from left to right, and one by one), clear solution; with sonication.
(Please use freshly prepared in vivo formulations for optimal results.) |
| Preparing Stock Solutions | 1 mg | 5 mg | 10 mg | |
| 1 mM | 1.9824 mL | 9.9120 mL | 19.8240 mL | |
| 5 mM | 0.3965 mL | 1.9824 mL | 3.9648 mL | |
| 10 mM | 0.1982 mL | 0.9912 mL | 1.9824 mL |
*Note: Please select an appropriate solvent for the preparation of stock solution based on your experiment needs. For most products, DMSO can be used for preparing stock solutions (e.g. 5 mM, 10 mM, or 20 mM concentration); some products with high aqueous solubility may be dissolved in water directly. Solubility information is available at the above Solubility Data section. Once the stock solution is prepared, aliquot it to routine usage volumes and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles.
Calculation results
Working concentration： mg/mL；
Method for preparing DMSO stock solution： mg drug pre-dissolved in μL DMSO (stock solution concentration mg/mL). Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:：Take μL DMSO stock solution, next add μL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O，mix and clarify.
(1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
(2) Be sure to add the solvent(s) in order.
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