![Dichloro[1,1'-bis(diphenylphosphino)ferrocene]palladium(II) dichloromethane adduct](/upload/1124/V64170.png)
| Size | Price | Stock | Qty |
|---|---|---|---|
| 5g |
|
||
| Other Sizes |
| Targets |
Dichloro[1,1'-bis(diphenylphosphino)ferrocene]palladium(II) dichloromethane adduct does not have a specific biological target. It is a chemical reagent used as a catalyst in organic synthesis. Its primary function is to facilitate cross-coupling and carbonylation reactions in the synthesis of various organic compounds.
|
|---|---|
| ln Vitro |
The compound is not evaluated for traditional in vitro biological activity. Its "activity" is catalytic, referring to its role as a palladium catalyst in organic synthesis for Suzuki, Stille, and carbonylation reactions.
|
| ln Vivo |
No in vivo activity is applicable for Dichloro[1,1'-bis(diphenylphosphino)ferrocene]palladium(II) dichloromethane adduct, as it is not a therapeutic agent. Its use is confined to the laboratory for organic synthesis. The compound is not administered to living organisms for any biological effect.
|
| Enzyme Assay |
The compound is used as a catalyst in organic synthesis. A typical procedure involves its use in a Suzuki coupling reaction between an aryl halide and a boronic acid. The reaction is carried out in a suitable solvent with a base, and the product is isolated by standard workup and purification techniques.
|
| Cell Assay |
Dichloro[1,1'-bis(diphenylphosphino)ferrocene]palladium(II) dichloromethane adduct is not used in standard cell culture for pharmacological studies. It is a chemical reagent used in organic synthesis to prepare compounds that may later be tested in biological systems. The compound itself is not added to cell culture media.
|
| Animal Protocol |
Animal studies are not conducted with Dichloro[1,1'-bis(diphenylphosphino)ferrocene]palladium(II) dichloromethane adduct as an active compound. Its purpose is to serve as a catalyst for the synthesis of compounds that may later be tested in vivo. The compound is never administered to animals for therapeutic or investigative purposes.
|
| ADME/Pharmacokinetics |
Pharmacokinetic properties are not relevant for Dichloro[1,1'-bis(diphenylphosphino)ferrocene]palladium(II) dichloromethane adduct, as it is not a therapeutic agent. Its chemical properties include a molecular weight of 816.64 g/mol and a molecular formula of C35H30Cl4FeP2Pd.
|
| Toxicity/Toxicokinetics |
Toxicological data for Dichloro[1,1'-bis(diphenylphosphino)ferrocene]palladium(II) dichloromethane adduct are not extensively detailed, as it is a research compound. It is not intended for human or veterinary use. Standard laboratory safety precautions, including the use of personal protective equipment (PPE), should be followed when handling the compound.
|
| Additional Infomation |
Dichloro[1,1'-bis(diphenylphosphino)ferrocene]palladium(II) dichloromethane adduct is a research-grade compound used as a catalyst in organic synthesis for Suzuki, Stille, and carbonylation reactions. It is a valuable tool for preparing complex organic molecules, including pharmaceuticals and agrochemicals. The compound is not approved for therapeutic use and is strictly for laboratory research.
|
| Molecular Formula |
C35H30CL4FEP2PD
|
|---|---|
| Molecular Weight |
816.64
|
| Exact Mass |
823.974
|
| CAS # |
95464-05-4
|
| PubChem CID |
51341998
|
| Appearance |
Orange to red solid powder
|
| Density |
1 g/cm3
|
| Melting Point |
275-280ºC(lit.)
|
| LogP |
10.921
|
| Hydrogen Bond Donor Count |
0
|
| Rotatable Bond Count |
6
|
| Heavy Atom Count |
43
|
| Complexity |
504
|
| Defined Atom Stereocenter Count |
0
|
| SMILES |
[CH-]1C=CC(=C1)P(C2=CC=CC=C2)C3=CC=CC=C3.[CH-]1C=CC(=C1)P(C2=CC=CC=C2)C3=CC=CC=C3.C(Cl)Cl.Cl[Pd]Cl.[Fe+2]
|
| InChi Key |
SNRCKKQHDUIRIY-UHFFFAOYSA-L
|
| InChi Code |
InChI=1S/2C17H14P.CH2Cl2.2ClH.Fe.Pd/c2*1-3-9-15(10-4-1)18(17-13-7-8-14-17)16-11-5-2-6-12-16;2-1-3;;;;/h2*1-14H;1H2;2*1H;;/q2*-1;;;;2*+2/p-2
|
| Chemical Name |
bis(cyclopenta-1,4-dien-1-yl(diphenyl)phosphane);dichloromethane;dichloropalladium;iron(2+)
|
| HS Tariff Code |
2934.99.9001
|
| Storage |
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month Note: (1). This product requires protection from light (avoid light exposure) during transportation and storage. (2). Please store this product in a sealed and protected environment (e.g. under nitrogen), avoid exposure to moisture. |
| Shipping Condition |
Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)
|
| Solubility (In Vitro) |
DMSO: 12.5 mg/mL (15.31 mM)
|
|---|---|
| Solubility (In Vivo) |
Solubility in Formulation 1: ≥ 1.25 mg/mL (1.53 mM) (saturation unknown) in 10% DMSO + 40% PEG300 +5% Tween-80 + 45% Saline (add these co-solvents sequentially from left to right, and one by one), clear solution.
For example, if 1 mL of working solution is to be prepared, you can add 100 μL of 12.5 mg/mL clear DMSO stock solution to 400 μL PEG300 and mix evenly; then add 50 μL Tween-80 + to the above solution and mix evenly; then add 450 μL normal saline to adjust the volume to 1 mL. Preparation of saline: Dissolve 0.9 g of sodium chloride in 100 mL ddH₂ O to obtain a clear solution. (Please use freshly prepared in vivo formulations for optimal results.) |
| Preparing Stock Solutions | 1 mg | 5 mg | 10 mg | |
| 1 mM | 1.2245 mL | 6.1226 mL | 12.2453 mL | |
| 5 mM | 0.2449 mL | 1.2245 mL | 2.4491 mL | |
| 10 mM | 0.1225 mL | 0.6123 mL | 1.2245 mL |
*Note: Please select an appropriate solvent for the preparation of stock solution based on your experiment needs. For most products, DMSO can be used for preparing stock solutions (e.g. 5 mM, 10 mM, or 20 mM concentration); some products with high aqueous solubility may be dissolved in water directly. Solubility information is available at the above Solubility Data section. Once the stock solution is prepared, aliquot it to routine usage volumes and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles.
Calculation results
Working concentration： mg/mL；
Method for preparing DMSO stock solution： mg drug pre-dissolved in μL DMSO (stock solution concentration mg/mL). Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:：Take μL DMSO stock solution, next add μL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O，mix and clarify.
(1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
(2) Be sure to add the solvent(s) in order.
Products are for research use only; We do not sell to patients
Copyright 2020 InvivoChem LLC | All Rights Reserved
