| Size | Price | Stock | Qty |
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| 50mg |
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| 100mg |
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| 250mg |
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| Other Sizes |
| Targets |
2-Amino-1,3-bis(carboxylethoxy)propane hydrochloride targets metal ions as a chelating agent. The compound's carboxylate groups and amino group provide coordination sites for binding metal ions such as calcium, magnesium, iron, and copper. This chelating property makes it useful for studying metal ion interactions and for applications in coordination chemistry. Its role as a linker suggests it can be used to connect different molecular components. Further research is needed to identify any specific biological targets.
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| ln Vitro |
In vitro studies of 2-Amino-1,3-bis(carboxylethoxy)propane hydrochloride have focused on its role as a chelating agent and linker in research applications. The compound's ability to bind metal ions has been characterized using spectroscopic and analytical methods. Its use in coordination chemistry and materials science has been documented. Its purity and identity are assessed using analytical chemistry methods. These in vitro studies provide foundational data for understanding the compound's utility in research applications.
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| ln Vivo |
In vivo studies of 2-Amino-1,3-bis(carboxylethoxy)propane hydrochloride are not applicable, as the compound is primarily used as a research chemical for in vitro applications. The compound is not intended for administration to living organisms. Its applications are limited to chemical research and materials science. The compound is not approved for human therapeutic use and is intended for research purposes only.
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| Enzyme Assay |
In vitro chemical assays for 2-Amino-1,3-bis(carboxylethoxy)propane hydrochloride involve testing its chelating properties and purity. The compound's ability to bind metal ions is assessed using spectroscopic methods such as UV-Vis spectroscopy or fluorescence spectroscopy. Its purity and identity are assessed using nuclear magnetic resonance spectroscopy, high-performance liquid chromatography, and mass spectrometry. All assays are performed with appropriate controls and standardized protocols to ensure reproducibility of results.
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| Cell Assay |
In vitro cell-based assays for 2-Amino-1,3-bis(carboxylethoxy)propane hydrochloride are limited, as the compound is primarily used as a chemical reagent rather than a biological agent. Its potential cytotoxicity or biological effects would be evaluated in the context of its use as a chelating agent. Cells could be treated with varying concentrations of the compound and cell viability assessed using MTT or similar colorimetric assays. However, comprehensive cell-based studies specifically targeting this compound are not well documented in the available literature.
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| Animal Protocol |
In vivo animal experiments for 2-Amino-1,3-bis(carboxylethoxy)propane hydrochloride are not well documented, as the compound is primarily used as a research chemical for in vitro applications. For toxicology studies, animals may be administered the compound to evaluate its safety profile. Parameters assessed would include body weight, organ weights, and histopathology. Control groups receiving vehicle alone would be included for comparison. All procedures would comply with institutional animal care and use committee guidelines. Comprehensive in vivo studies are not well documented in the available literature.
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| ADME/Pharmacokinetics |
The pharmacokinetic properties of 2-Amino-1,3-bis(carboxylethoxy)propane hydrochloride reflect its nature as a small chelating compound. It has a molecular weight consistent with its structure. As a hydrophilic compound with carboxylate groups, it has limited absorption through the gastrointestinal tract. The compound is expected to be excreted through the kidneys. Complete pharmacokinetic profiling including absorption, distribution, metabolism, and excretion would require further systematic studies.
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| Toxicity/Toxicokinetics |
The toxicity profile of 2-Amino-1,3-bis(carboxylethoxy)propane hydrochloride has been evaluated in the context of its use as a research chemical. As a chelating agent, it may affect metal ion homeostasis in biological systems. Proper handling procedures including use of personal protective equipment are recommended when working with pure compound. The compound is not approved for human therapeutic use and is intended for research purposes only. Long-term toxicity studies would be needed to fully establish its safety profile.
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| Additional Infomation |
2-Amino-1,3-bis(carboxylethoxy)propane hydrochloride (CAS# 2421153-68-4) is a chemical compound used as a chelating agent or linker in research applications. The compound features an amino group and two carboxylethoxy groups attached to a propane backbone, with a hydrochloride salt form. It is used in coordination chemistry, materials science, and as a building block for the synthesis of more complex molecules. The compound is intended for research use only and is not for human therapeutic use.
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| Molecular Formula |
C9H18CLNO6
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|---|---|
| Molecular Weight |
271.69532251358
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| Exact Mass |
271.082
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| CAS # |
2421153-68-4
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| Related CAS # |
2-Amino-1,3-bis(carboxylethoxy)propane;1020112-73-5
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| PubChem CID |
146013773
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| Appearance |
White to off-white solid
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| Hydrogen Bond Donor Count |
4
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| Hydrogen Bond Acceptor Count |
7
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| Rotatable Bond Count |
10
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| Heavy Atom Count |
17
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| Complexity |
198
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| Defined Atom Stereocenter Count |
0
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| SMILES |
Cl.O(CCC(=O)O)CC(COCCC(=O)O)N
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| InChi Key |
UJVQKTLFWZAURM-UHFFFAOYSA-N
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| InChi Code |
InChI=1S/C9H17NO6.ClH/c10-7(5-15-3-1-8(11)12)6-16-4-2-9(13)14;/h7H,1-6,10H2,(H,11,12)(H,13,14);1H
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| Chemical Name |
3-[2-amino-3-(2-carboxyethoxy)propoxy]propanoic acid;hydrochloride
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| HS Tariff Code |
2934.99.9001
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| Storage |
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month Note: Please store this product in a sealed and protected environment, avoid exposure to moisture. |
| Shipping Condition |
Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)
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| Solubility (In Vitro) |
DMSO: ~200 mg/mL (~736.1 mM; with ultrasonication)
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|---|---|
| Solubility (In Vivo) |
Solubility in Formulation 1: ≥ 5 mg/mL (18.40 mM) (saturation unknown) in 10% DMSO + 40% PEG300 + 5% Tween-80 + 45% Saline (add these co-solvents sequentially from left to right, and one by one), Clear solution.
For example, if 1 mL of working solution is to be prepared, you can add 100 μL of DMSO stock solution (50.0 mg/mL) to 400 μL of PEG300 and mix well; then add 50 μL of Tween-80 and mix well; finally add 450 μL of physiological saline and adjust the volume to 1 mL. Preparation of saline: Dissolve 0.9 g of sodium chloride in 100 mL ddH₂ O to obtain a clear solution. Solubility in Formulation 2: ≥ 5 mg/mL (18.40 mM) (saturation unknown) in 10% DMSO + 90% (20% SBE-β-CD in Saline) (add these co-solvents sequentially from left to right, and one by one), Clear solution. For example, if 1 mL of working solution is to be prepared, you can add 100 μL of DMSO stock solution (50.0 mg/mL) to 900 μL of 20% SBE-β-CD saline and mix well. Preparation of 20% SBE-β-CD in Saline (4°C，1 week): Dissolve 2 g SBE-β-CD in 10 mL saline to obtain a clear solution. Solubility in Formulation 3: ≥ 5 mg/mL (18.40 mM) (saturation unknown) in 10% DMSO + 90% Corn Oil (add these co-solvents sequentially from left to right, and one by one), Clear solution. For example, if 1 mL of working solution is to be prepared, you can add 100 μL of DMSO stock solution (50.0 mg/mL) to 900 μL of corn oil and mix well. (Please use freshly prepared in vivo formulations for optimal results.) |
| Preparing Stock Solutions | 1 mg | 5 mg | 10 mg | |
| 1 mM | 3.6805 mL | 18.4026 mL | 36.8053 mL | |
| 5 mM | 0.7361 mL | 3.6805 mL | 7.3611 mL | |
| 10 mM | 0.3681 mL | 1.8403 mL | 3.6805 mL |
*Note: Please select an appropriate solvent for the preparation of stock solution based on your experiment needs. For most products, DMSO can be used for preparing stock solutions (e.g. 5 mM, 10 mM, or 20 mM concentration); some products with high aqueous solubility may be dissolved in water directly. Solubility information is available at the above Solubility Data section. Once the stock solution is prepared, aliquot it to routine usage volumes and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles.
Calculation results
Working concentration： mg/mL；
Method for preparing DMSO stock solution： mg drug pre-dissolved in μL DMSO (stock solution concentration mg/mL). Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:：Take μL DMSO stock solution, next add μL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O，mix and clarify.
(1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
(2) Be sure to add the solvent(s) in order.
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