| Size | Price | |
|---|---|---|
| Other Sizes |
| Targets |
Not applicable (chemical reagent). N-Methylbenzylamine is a chemical reagent used in organic synthesis. It does not have a specific biological target. The compound is used as a building block for the synthesis of pharmaceuticals, agrochemicals, and other bioactive compounds. Its biological effects, if any, would be related to the compounds synthesized from it rather than the reagent itself.
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|---|---|
| ln Vitro |
N-Methylbenzylamine is a chemical reagent used in organic synthesis. It is used as a building block for the synthesis of pharmaceuticals, agrochemicals, and other bioactive compounds. As a chemical reagent, it does not have direct in vitro biological activity. The compound may be used in studies of amine chemistry and as a reference standard for analytical applications.
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| ln Vivo |
In vivo studies of N-methylbenzylamine are not applicable as the compound is a chemical reagent rather than a pharmacologically active compound. It is used in organic synthesis to produce bioactive compounds that may be evaluated in vivo. The compound itself is not administered to animals for therapeutic or pharmacological studies.
|
| Enzyme Assay |
Non-cell-based assays for N-methylbenzylamine are primarily analytical in nature. Standard analytical methods including HPLC, GC, NMR, and mass spectrometry are used for compound characterization and purity assessment. The compound is used as a reactant in organic synthesis reactions, and its reactivity and purity are assessed using standard organic chemistry methods.
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| Cell Assay |
Cell-based assays for N-methylbenzylamine are not commonly performed, as the compound is a chemical reagent rather than a pharmacologically active compound. Compounds synthesized using this reagent may be tested in cell-based assays, but the reagent itself is not typically used in cell culture applications.
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| Animal Protocol |
In vivo animal studies for N-methylbenzylamine are not applicable as the compound is a chemical reagent rather than a pharmacologically active compound. It is used in organic synthesis to produce compounds that may be evaluated in animal models.
|
| ADME/Pharmacokinetics |
N-Methylbenzylamine has a molecular formula of C₈H₁₁N and a molecular weight of approximately 121.18 g/mol. The CAS number is 103-67-3. It is a secondary amine consisting of a benzyl group attached to a methylamino group. The compound is used as a building block in organic synthesis and as a research chemical. It should be stored under recommended conditions. It is intended for research use only.
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| Toxicity/Toxicokinetics |
Specific toxicity data for N-methylbenzylamine are limited. As an amine, it may cause irritation to the skin, eyes, and respiratory tract. Standard laboratory safety practices should be followed when handling this compound, including the use of personal protective equipment. It is intended for research use only.
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| Additional Infomation |
N-Methylbenzylamine is the parent compound
N-Methylbenzylamine is an organic compound used as a building block in organic synthesis, as a precursor for the synthesis of pharmaceuticals, agrochemicals, and other bioactive compounds. It is a secondary amine consisting of a benzyl group attached to a methylamino group. The compound is also used as a research chemical for studying amine chemistry and as a reference standard for analytical applications. It is for research use only. |
| Molecular Formula |
C8H11N
|
|---|---|
| Molecular Weight |
121.18
|
| Exact Mass |
121.089
|
| CAS # |
103-67-3
|
| Related CAS # |
N-Methylbenzylamine-d3; 122025-09-6
|
| PubChem CID |
7669
|
| Appearance |
Colorless to light yellow liquid
|
| Density |
0.9±0.1 g/cm3
|
| Boiling Point |
180.5±0.0 °C at 760 mmHg
|
| Melting Point |
-24 °C
|
| Flash Point |
77.8±0.0 °C
|
| Vapour Pressure |
0.9±0.3 mmHg at 25°C
|
| Index of Refraction |
1.513
|
| LogP |
1.52
|
| Hydrogen Bond Donor Count |
1
|
| Hydrogen Bond Acceptor Count |
1
|
| Rotatable Bond Count |
2
|
| Heavy Atom Count |
9
|
| Complexity |
65
|
| Defined Atom Stereocenter Count |
0
|
| SMILES |
N([H])(C([H])([H])[H])C([H])([H])C1C([H])=C([H])C([H])=C([H])C=1[H]
|
| InChi Key |
RIWRFSMVIUAEBX-UHFFFAOYSA-N
|
| InChi Code |
InChI=1S/C8H11N/c1-9-7-8-5-3-2-4-6-8/h2-6,9H,7H2,1H3
|
| Chemical Name |
N-methyl-1-phenylmethanamine
|
| Synonyms |
N-Methylbenzylamine
|
| HS Tariff Code |
2934.99.9001
|
| Storage |
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month Note: This product requires protection from light (avoid light exposure) during transportation and storage. |
| Shipping Condition |
Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)
|
| Solubility (In Vitro) |
DMSO: 100 mg/mL (825.22 mM)
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|---|---|
| Solubility (In Vivo) |
Solubility in Formulation 1: ≥ 2.5 mg/mL (20.63 mM) (saturation unknown) in 10% DMSO + 40% PEG300 + 5% Tween80 + 45% Saline (add these co-solvents sequentially from left to right, and one by one), clear solution.
For example, if 1 mL of working solution is to be prepared, you can add 100 μL of 25.0 mg/mL clear DMSO stock solution to 400 μL PEG300 and mix evenly; then add 50 μL Tween-80 to the above solution and mix evenly; then add 450 μL normal saline to adjust the volume to 1 mL. Preparation of saline: Dissolve 0.9 g of sodium chloride in 100 mL ddH₂ O to obtain a clear solution. Solubility in Formulation 2: ≥ 2.5 mg/mL (20.63 mM) (saturation unknown) in 10% DMSO + 90% (20% SBE-β-CD in Saline) (add these co-solvents sequentially from left to right, and one by one), clear solution. For example, if 1 mL of working solution is to be prepared, you can add 100 μL of 25.0 mg/mL clear DMSO stock solution to 900 μL of 20% SBE-β-CD physiological saline solution and mix evenly. Preparation of 20% SBE-β-CD in Saline (4°C，1 week): Dissolve 2 g SBE-β-CD in 10 mL saline to obtain a clear solution. View More
Solubility in Formulation 3: ≥ 2.5 mg/mL (20.63 mM) (saturation unknown) in 10% DMSO + 90% Corn Oil (add these co-solvents sequentially from left to right, and one by one), clear solution. |
| Preparing Stock Solutions | 1 mg | 5 mg | 10 mg | |
| 1 mM | 8.2522 mL | 41.2609 mL | 82.5219 mL | |
| 5 mM | 1.6504 mL | 8.2522 mL | 16.5044 mL | |
| 10 mM | 0.8252 mL | 4.1261 mL | 8.2522 mL |
*Note: Please select an appropriate solvent for the preparation of stock solution based on your experiment needs. For most products, DMSO can be used for preparing stock solutions (e.g. 5 mM, 10 mM, or 20 mM concentration); some products with high aqueous solubility may be dissolved in water directly. Solubility information is available at the above Solubility Data section. Once the stock solution is prepared, aliquot it to routine usage volumes and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles.
Calculation results
Working concentration： mg/mL；
Method for preparing DMSO stock solution： mg drug pre-dissolved in μL DMSO (stock solution concentration mg/mL). Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:：Take μL DMSO stock solution, next add μL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O，mix and clarify.
(1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
(2) Be sure to add the solvent(s) in order.
Link: https://clinicaltrials.gov/ct2/show/NCT05531526
Conditions:Alzheimer DiseaseLink: https://clinicaltrials.gov/ct2/show/NCT03625622
Conditions:Mild to Moderate Alzheimer's DiseaseProducts are for research use only; We do not sell to patients
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