| Size | Price | Stock | Qty |
|---|---|---|---|
| 500mg |
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| Other Sizes |
| Targets |
1,3-Dimethylpyrazole does not have a well-defined pharmacological target. As a heterocyclic compound, it may exert its biological effects through interaction with various cellular targets. The compound is commonly used as a ligand in coordination chemistry, forming metal complexes. Its presence in bamboo suggests potential biological activities, but these are not well-characterized.
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|---|---|
| ln Vitro |
In vitro, 1,3-Dimethylpyrazole is a bioactive compound isolated from Moso Bamboo Root. The compound's biological activities, if any, have not been extensively characterized. It is primarily used as a ligand in coordination chemistry. Its activity in cellular assays, if studied, would be concentration-dependent. However, specific in vitro activity data are limited.
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| ln Vivo |
In vivo, 1,3-Dimethylpyrazole has not been extensively studied as a therapeutic agent. It is a bioactive compound found in bamboo. The compound is not administered to animals for therapeutic purposes. Its in vivo effects, if any, have not been characterized.
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| Enzyme Assay |
Non-cell-based assays for 1,3-Dimethylpyrazole involve characterization of its chemical properties. The compound's structure is confirmed by NMR and MS. Its purity is determined by GC. The compound's chemical properties including molecular formula (C₅H₈N₂) and molecular weight (96.13) are characterized. Its coordination chemistry properties are characterized for use as a ligand.
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| Cell Assay |
Cellular assays for 1,3-Dimethylpyrazole are not typically performed as the compound is primarily used as a ligand in coordination chemistry. The compound's biological activities, if any, have not been well-characterized. It is not commonly used in cell-based assays for pharmacological evaluation.
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| Animal Protocol |
1,3-Dimethylpyrazole is not used in animal experiments as a therapeutic agent. It is a chemical compound used primarily in synthetic organic chemistry as a ligand. The compound is not administered to animals for therapeutic purposes. Its use is limited to chemical synthesis and coordination chemistry.
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| ADME/Pharmacokinetics |
Pharmacokinetic properties are not applicable to 1,3-Dimethylpyrazole as it is not a therapeutic agent. The compound is a chemical reagent used in synthetic chemistry. Its chemical stability, solubility, and reactivity are characterized for research applications. No PK data are available as the compound is not a drug.
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| Toxicity/Toxicokinetics |
The toxicity of 1,3-Dimethylpyrazole has not been comprehensively evaluated as it is not a therapeutic agent. The compound is handled as a chemical reagent with standard laboratory safety precautions. As a heterocyclic compound, it may be irritating to skin, eyes, and respiratory tract. The compound is for research use only and is not intended for human consumption.
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| References | |
| Additional Infomation |
1,3-Dimethylpyrazole (CAS# 694-48-4) is a heterocyclic organic compound with the molecular formula C₅H₈N₂ and a molecular weight of 96.13. It is also known as 1,3-dimethyl-1H-pyrazole. The compound is a bioactive compound isolated from Moso Bamboo Root and is commonly used as a ligand in coordination chemistry. As of current knowledge, 1,3-Dimethylpyrazole is not approved as a therapeutic agent.
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| Molecular Formula |
C5H8N2
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|---|---|
| Molecular Weight |
96.13
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| Exact Mass |
96.068
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| CAS # |
694-48-4
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| PubChem CID |
79096
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| Appearance |
Colorless to light yellow liquid
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| Density |
1.0±0.1 g/cm3
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| Boiling Point |
140.2±9.0 °C at 760 mmHg
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| Flash Point |
38.6±18.7 °C
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| Vapour Pressure |
7.7±0.2 mmHg at 25°C
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| Index of Refraction |
1.519
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| LogP |
0.63
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| Hydrogen Bond Donor Count |
0
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| Hydrogen Bond Acceptor Count |
1
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| Rotatable Bond Count |
0
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| Heavy Atom Count |
7
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| Complexity |
63.1
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| Defined Atom Stereocenter Count |
0
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| SMILES |
C1=C[N](N=C1C)C
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| InChi Key |
NODLZCJDRXTSJO-UHFFFAOYSA-N
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| InChi Code |
InChI=1S/C5H8N2/c1-5-3-4-7(2)6-5/h3-4H,1-2H3
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| Chemical Name |
1,3-Dimethylpyrazole
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| Synonyms |
1,3-Dimethylpyrazole
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| HS Tariff Code |
2934.99.9001
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| Storage |
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month |
| Shipping Condition |
Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)
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| Solubility (In Vitro) |
DMSO: ≥ 100 mg/mL (1040.26 mM)
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|---|---|
| Solubility (In Vivo) |
Solubility in Formulation 1: ≥ 2.5 mg/mL (26.01 mM) (saturation unknown) in 10% DMSO + 40% PEG300 + 5% Tween80 + 45% Saline (add these co-solvents sequentially from left to right, and one by one), clear solution.
For example, if 1 mL of working solution is to be prepared, you can add 100 μL of 25.0 mg/mL clear DMSO stock solution to 400 μL PEG300 and mix evenly; then add 50 μL Tween-80 to the above solution and mix evenly; then add 450 μL normal saline to adjust the volume to 1 mL. Preparation of saline: Dissolve 0.9 g of sodium chloride in 100 mL ddH₂ O to obtain a clear solution. Solubility in Formulation 2: ≥ 2.5 mg/mL (26.01 mM) (saturation unknown) in 10% DMSO + 90% (20% SBE-β-CD in Saline) (add these co-solvents sequentially from left to right, and one by one), clear solution. For example, if 1 mL of working solution is to be prepared, you can add 100 μL of 25.0 mg/mL clear DMSO stock solution to 900 μL of 20% SBE-β-CD physiological saline solution and mix evenly. Preparation of 20% SBE-β-CD in Saline (4°C，1 week): Dissolve 2 g SBE-β-CD in 10 mL saline to obtain a clear solution. View More
Solubility in Formulation 3: ≥ 2.5 mg/mL (26.01 mM) (saturation unknown) in 10% DMSO + 90% Corn Oil (add these co-solvents sequentially from left to right, and one by one), clear solution. |
| Preparing Stock Solutions | 1 mg | 5 mg | 10 mg | |
| 1 mM | 10.4026 mL | 52.0129 mL | 104.0258 mL | |
| 5 mM | 2.0805 mL | 10.4026 mL | 20.8052 mL | |
| 10 mM | 1.0403 mL | 5.2013 mL | 10.4026 mL |
*Note: Please select an appropriate solvent for the preparation of stock solution based on your experiment needs. For most products, DMSO can be used for preparing stock solutions (e.g. 5 mM, 10 mM, or 20 mM concentration); some products with high aqueous solubility may be dissolved in water directly. Solubility information is available at the above Solubility Data section. Once the stock solution is prepared, aliquot it to routine usage volumes and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles.
Calculation results
Working concentration： mg/mL；
Method for preparing DMSO stock solution： mg drug pre-dissolved in μL DMSO (stock solution concentration mg/mL). Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:：Take μL DMSO stock solution, next add μL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O，mix and clarify.
(1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
(2) Be sure to add the solvent(s) in order.
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