| Size | Price | |
|---|---|---|
| Other Sizes |
| Targets |
1-Nonadecanol does not have a specific pharmacological target as it is primarily used as a chemical intermediate. Long-chain fatty alcohols may interact with biological membranes and can be metabolized to fatty acids. Some long-chain alcohols have been studied for their potential health benefits, including cholesterol-lowering effects, but specific targets for 1-nonadecanol have not been identified.
|
|---|---|
| ln Vitro |
In vitro activity data for 1-nonadecanol are limited. As a long-chain fatty alcohol, it may exhibit surfactant properties and can interact with cell membranes. Some studies have investigated the biological activities of long-chain alcohols, but specific data for 1-nonadecanol are not available in the published literature.
|
| ln Vivo |
In vivo activity data for 1-nonadecanol are not available in the published literature. Long-chain fatty alcohols are generally metabolized to their corresponding fatty acids and may be incorporated into lipid metabolism pathways. However, specific pharmacological effects of 1-nonadecanol have not been reported.
|
| Enzyme Assay |
In vitro enzyme/receptor binding assays are not typically performed for 1-nonadecanol as it is primarily used as a chemical intermediate rather than a pharmacologically active compound. Standard analytical methods including GC and HPLC are used for purity assessment.
|
| Cell Assay |
Cellular assays are not typically performed with 1-nonadecanol as it is not a pharmacologically active compound. The compound is used in chemical synthesis and industrial applications.
|
| Animal Protocol |
In vivo animal studies are not typically performed with 1-nonadecanol for therapeutic evaluation. The compound is used as a chemical intermediate and is not intended for pharmacological applications.
|
| ADME/Pharmacokinetics |
Pharmacokinetic properties of 1-nonadecanol are not well characterized as the compound is not a therapeutic agent. As a long-chain fatty alcohol, it would be expected to be metabolized to nonadecanoic acid through oxidation.
|
| Toxicity/Toxicokinetics |
Specific toxicity data for 1-nonadecanol are limited. As a long-chain fatty alcohol, it is generally considered to have low toxicity. Standard laboratory safety precautions should be followed when handling the compound.
|
| References | |
| Additional Infomation |
Nonadecan-1-ol is a long-chain primary fatty alcohol formed by replacing a terminal methyl hydrogen atom with a hydroxyl group in the nonadecane compound. It is a plant metabolite, a fungal metabolite, and a component of volatile oils. It is a long-chain primary fatty alcohol and also a nonadecanol.
It has been reported that 1-nonadecanol exists in plants of the genus Euphorbia piscatoria, Gymnodinium nagasakiense, and other organisms with relevant data. 1-Nonadecanol is a long-chain primary alcohol used as a chemical intermediate in the synthesis of surfactants, lubricants, and specialty chemicals. It is found in various natural sources including plant waxes. The compound is not a drug and has no therapeutic applications. |
| Molecular Formula |
C19H40O
|
|---|---|
| Molecular Weight |
284.52
|
| Exact Mass |
284.307
|
| CAS # |
1454-84-8
|
| PubChem CID |
80281
|
| Appearance |
White to off-white solid
|
| Density |
0.8±0.1 g/cm3
|
| Boiling Point |
345.3±5.0 °C at 760 mmHg
|
| Melting Point |
60-61 °C(lit.)
|
| Flash Point |
140.4±5.2 °C
|
| Vapour Pressure |
0.0±1.7 mmHg at 25°C
|
| Index of Refraction |
1.452
|
| LogP |
8.85
|
| Hydrogen Bond Donor Count |
1
|
| Hydrogen Bond Acceptor Count |
1
|
| Rotatable Bond Count |
17
|
| Heavy Atom Count |
20
|
| Complexity |
156
|
| Defined Atom Stereocenter Count |
0
|
| SMILES |
O([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
|
| InChi Key |
XGFDHKJUZCCPKQ-UHFFFAOYSA-N
|
| InChi Code |
InChI=1S/C19H40O/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20/h20H,2-19H2,1H3
|
| Chemical Name |
nonadecan-1-ol
|
| HS Tariff Code |
2934.99.9001
|
| Storage |
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month |
| Shipping Condition |
Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)
|
| Solubility (In Vitro) |
DMSO: ≥ 10 mg/mL (35.15 mM)
|
|---|---|
| Solubility (In Vivo) |
Solubility in Formulation 1: 1 mg/mL (3.51 mM) in 10% DMSO + 40% PEG300 + 5% Tween80 + 45% Saline (add these co-solvents sequentially from left to right, and one by one), suspension solution; with sonication.
For example, if 1 mL of working solution is to be prepared, you can add 100 μL of 10.0 mg/mL clear DMSO stock solution to 400 μL of PEG300 and mix evenly; then add 50 μL of Tween-80 to the above solution and mix evenly; then add 450 μL of normal saline to adjust the volume to 1 mL. Preparation of saline: Dissolve 0.9 g of sodium chloride in 100 mL ddH₂ O to obtain a clear solution. Solubility in Formulation 2: 1 mg/mL (3.51 mM) in 10% DMSO + 90% (20% SBE-β-CD in Saline) (add these co-solvents sequentially from left to right, and one by one), suspension solution; with ultrasonication. For example, if 1 mL of working solution is to be prepared, you can add 100 μL of 10.0 mg/mL clear DMSO stock solution to 900 μL of 20% SBE-β-CD physiological saline solution and mix evenly. Preparation of 20% SBE-β-CD in Saline (4°C，1 week): Dissolve 2 g SBE-β-CD in 10 mL saline to obtain a clear solution. View More
Solubility in Formulation 3: ≥ 1 mg/mL (3.51 mM) (saturation unknown) in 10% DMSO + 90% Corn Oil (add these co-solvents sequentially from left to right, and one by one), clear solution. |
| Preparing Stock Solutions | 1 mg | 5 mg | 10 mg | |
| 1 mM | 3.5147 mL | 17.5735 mL | 35.1469 mL | |
| 5 mM | 0.7029 mL | 3.5147 mL | 7.0294 mL | |
| 10 mM | 0.3515 mL | 1.7573 mL | 3.5147 mL |
*Note: Please select an appropriate solvent for the preparation of stock solution based on your experiment needs. For most products, DMSO can be used for preparing stock solutions (e.g. 5 mM, 10 mM, or 20 mM concentration); some products with high aqueous solubility may be dissolved in water directly. Solubility information is available at the above Solubility Data section. Once the stock solution is prepared, aliquot it to routine usage volumes and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles.
Calculation results
Working concentration： mg/mL；
Method for preparing DMSO stock solution： mg drug pre-dissolved in μL DMSO (stock solution concentration mg/mL). Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:：Take μL DMSO stock solution, next add μL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O，mix and clarify.
(1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
(2) Be sure to add the solvent(s) in order.
Products are for research use only; We do not sell to patients
Copyright 2020 InvivoChem LLC | All Rights Reserved
