| Size | Price | Stock | Qty |
|---|---|---|---|
| 5g |
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| Other Sizes |
| Targets |
(R)-(-)-2-Butanol does not have a specific biological target as a therapeutic agent. It is a chiral chemical reagent used primarily as a building block for organic synthesis and as an analytical standard. Its biological effects, if any, would be related to its solvent properties or metabolism as a short-chain alcohol.
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|---|---|
| ln Vitro |
(R)-(-)-2-Butanol is a chemical reagent and does not possess intrinsic biological activity. It is used as a chiral building block in organic synthesis and as an analytical standard. No specific in vitro biological activity data are available for this compound.
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| ln Vivo |
The compound is not intended for in vivo use as a therapeutic agent. It is a research chemical used for synthetic and analytical purposes. No pharmacological or toxicological in vivo studies have been reported.
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| Enzyme Assay |
(R)-(-)-2-Butanol is not used in enzyme/receptor binding assays. As a chemical reagent, it is used in organic synthesis and as a chiral standard in analytical chemistry. Standard protocols involve its use as a solvent, reagent, or reference material in chromatographic and spectroscopic analyses.
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| Cell Assay |
No cell-based assay protocols are applicable for this compound. It is a chemical reagent used for synthetic and analytical purposes, not for cellular studies.
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| Animal Protocol |
No in vivo animal experiment protocols are applicable for (R)-(-)-2-Butanol. As a chemical reagent, it is not administered to animals for therapeutic or pharmacological studies.
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| ADME/Pharmacokinetics |
Pharmacokinetic data are not applicable for (R)-(-)-2-Butanol as it is a chemical reagent, not a pharmaceutical agent. It is not intended for systemic administration.
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| Toxicity/Toxicokinetics |
The compound is flammable with a flash point of 22°C. It may cause irritation upon contact with skin, eyes, or mucous membranes. Standard laboratory safety precautions should be followed when handling the compound.
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| References |
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| Additional Infomation |
(2R)-But-2-ol is a but-2-ol. It is the enantiomer of (2S)-But-2-ol.
See also: 2-Butanol (note moved to). (R)-(-)-2-Butanol ((R)-butan-2-ol) is the (R)-enantiomer of sec-butyl alcohol, used as a chiral building block and analytical standard in organic synthesis and research. It has a molecular weight of 74.12 g/mol and a density of 0.807 g/mL. It is not a drug and has no clinical applications or approvals. |
| Molecular Formula |
C4H10O
|
|---|---|
| Molecular Weight |
74.12
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| Exact Mass |
147.089
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| CAS # |
14898-79-4
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| PubChem CID |
84682
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| Appearance |
Colorless to light yellow liquid
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| Density |
0.807
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| Boiling Point |
99-100ºC
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| Melting Point |
-114ºC
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| Flash Point |
26ºC
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| Vapour Pressure |
25.2mmHg at 25°C
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| Index of Refraction |
1.396-1.398
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| LogP |
0.777
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| Hydrogen Bond Donor Count |
1
|
| Hydrogen Bond Acceptor Count |
1
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| Rotatable Bond Count |
1
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| Heavy Atom Count |
5
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| Complexity |
19.6
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| Defined Atom Stereocenter Count |
1
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| SMILES |
CC[C@@H](C)O
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| InChi Key |
BTANRVKWQNVYAZ-SCSAIBSYSA-N
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| InChi Code |
InChI=1S/C4H10O/c1-3-4(2)5/h4-5H,3H2,1-2H3/t4-/m1/s1
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| Chemical Name |
(2R)-butan-2-ol
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| HS Tariff Code |
2934.99.9001
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| Storage |
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month |
| Shipping Condition |
Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)
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| Solubility (In Vitro) |
DMSO: 100 mg/mL (1349.16 mM)
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|---|---|
| Solubility (In Vivo) |
Solubility in Formulation 1: ≥ 2.5 mg/mL (33.73 mM) (saturation unknown) in 10% DMSO + 40% PEG300 + 5% Tween80 + 45% Saline (add these co-solvents sequentially from left to right, and one by one), clear solution.
For example, if 1 mL of working solution is to be prepared, you can add 100 μL of 25.0 mg/mL clear DMSO stock solution to 400 μL PEG300 and mix evenly; then add 50 μL Tween-80 to the above solution and mix evenly; then add 450 μL normal saline to adjust the volume to 1 mL. Preparation of saline: Dissolve 0.9 g of sodium chloride in 100 mL ddH₂ O to obtain a clear solution. Solubility in Formulation 2: ≥ 2.5 mg/mL (33.73 mM) (saturation unknown) in 10% DMSO + 90% (20% SBE-β-CD in Saline) (add these co-solvents sequentially from left to right, and one by one), clear solution. For example, if 1 mL of working solution is to be prepared, you can add 100 μL of 25.0 mg/mL clear DMSO stock solution to 900 μL of 20% SBE-β-CD physiological saline solution and mix evenly. Preparation of 20% SBE-β-CD in Saline (4°C，1 week): Dissolve 2 g SBE-β-CD in 10 mL saline to obtain a clear solution. View More
Solubility in Formulation 3: ≥ 2.5 mg/mL (33.73 mM) (saturation unknown) in 10% DMSO + 90% Corn Oil (add these co-solvents sequentially from left to right, and one by one), clear solution. |
| Preparing Stock Solutions | 1 mg | 5 mg | 10 mg | |
| 1 mM | 13.4916 mL | 67.4582 mL | 134.9164 mL | |
| 5 mM | 2.6983 mL | 13.4916 mL | 26.9833 mL | |
| 10 mM | 1.3492 mL | 6.7458 mL | 13.4916 mL |
*Note: Please select an appropriate solvent for the preparation of stock solution based on your experiment needs. For most products, DMSO can be used for preparing stock solutions (e.g. 5 mM, 10 mM, or 20 mM concentration); some products with high aqueous solubility may be dissolved in water directly. Solubility information is available at the above Solubility Data section. Once the stock solution is prepared, aliquot it to routine usage volumes and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles.
Calculation results
Working concentration： mg/mL；
Method for preparing DMSO stock solution： mg drug pre-dissolved in μL DMSO (stock solution concentration mg/mL). Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:：Take μL DMSO stock solution, next add μL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O，mix and clarify.
(1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
(2) Be sure to add the solvent(s) in order.
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